Articles producció científica> Bioquímica i Biotecnologia

Gut Microbiota Influences the Photoperiod Effects on Proanthocyanidins Bioavailability in Diet-Induced Obese Rats

  • Identification data

    Identifier: imarina:9292143
  • Authors:

    Arreaza-Gil, V
    Escobar-Martinez, I
    Mulero, M
    Muguerza, B
    Suarez, M
    Arola-Arnal, A
    Torres-Fuentes, C
  • Others:

    Author, as appears in the article.: Arreaza-Gil, V; Escobar-Martinez, I; Mulero, M; Muguerza, B; Suarez, M; Arola-Arnal, A; Torres-Fuentes, C
    Department: Bioquímica i Biotecnologia
    URV's Author/s: Alkhoury, Nadine / Arola Arnal, Anna / Arreaza Gil, Verónica / Muguerza Marquínez, Maria Begoña / Mulero Abellán, Miguel / Suárez Recio, Manuel / Torres Fuentes, Cristina
    Keywords: Seasonal rhythms Obesity Gut microbiota Gspe Grape seed proanthocyanidins Bioavailability xenohormesis seasonal rhythms polyphenols plasma kinetics obesity metabolic syndrome healthy gut microbiota gspe flavanols flavan-3-ols blood-pressure 3-hydroxyphenylacetic acid
    Abstract: Polyphenols health effects on obesity are mainly attributed to their metabolites generated after their gastrointestinal digestion, in which gut microbiota plays an important role. Moreover, gut microbiota composition and polyphenols bioavailability are influenced by differences in day light length (photoperiod). Thus, this study evaluated if a grape seed proanthocyanidins extract (GSPE) bioavailability is influenced by different photoperiod exposure via gut microbiota modulation in an obesogenic context.Cafeteria diet-induced obese Fischer 344 rats were housed under different photoperiod conditions (6, 12 or 18 h of light per day) during 9 weeks and administered with GSPE (25 mg/kg) or GSPE and an antibiotic cocktail (ABX) for the last 4 weeks. Serum GSPE-derived metabolites were quantified by HPLC-MS/MS.A higher bioavailability was observed under L6 compared to L18. Individual metabolites, especially those from the gut microbiota, were affected by photoperiods. ABX treatment altered these photoperiod-mediated changes. Therefore, these results suggest that gut microbiota plays a key role in the photoperiod effects on GSPE bioavailability in obese rats. This article is protected by copyright. All rights reserved.This article is protected by copyright. All rights reserved.
    Thematic Areas: Saúde coletiva Química Nutrição Medicina veterinaria Medicina ii Medicina i Interdisciplinar Food science & technology Food science Farmacia Educação física Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología Biotechnology Astronomia / física
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: cristina.torres@urv.cat begona.muguerza@urv.cat anna.arola@urv.cat miquel.mulero@urv.cat manuel.suarez@urv.cat veronica.arreaza@estudiants.urv.cat veronica.arreaza@estudiants.urv.cat nadine.alkhoury@estudiants.urv.cat nadine.alkhoury@estudiants.urv.cat nadine.alkhoury@estudiants.urv.cat nadine.alkhoury@estudiants.urv.cat
    Author identifier: 0000-0002-2917-6910 0000-0001-7384-8588 0000-0001-6529-1345 0000-0003-0122-8253 0000-0002-8301-2095 0000-0002-8301-2095
    Record's date: 2024-06-22
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://onlinelibrary.wiley.com/doi/full/10.1002/mnfr.202200600
    Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Molecular Nutrition & Food Research. e2200600-e2200600
    APA: Arreaza-Gil, V; Escobar-Martinez, I; Mulero, M; Muguerza, B; Suarez, M; Arola-Arnal, A; Torres-Fuentes, C (2023). Gut Microbiota Influences the Photoperiod Effects on Proanthocyanidins Bioavailability in Diet-Induced Obese Rats. Molecular Nutrition & Food Research, (), e2200600-e2200600. DOI: 10.1002/mnfr.202200600
    Article's DOI: 10.1002/mnfr.202200600
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2023
    Publication Type: Journal Publications
  • Keywords:

    Biotechnology,Food Science,Food Science & Technology
    Seasonal rhythms
    Obesity
    Gut microbiota
    Gspe
    Grape seed proanthocyanidins
    Bioavailability
    xenohormesis
    seasonal rhythms
    polyphenols
    plasma kinetics
    obesity
    metabolic syndrome
    healthy
    gut microbiota
    gspe
    flavanols
    flavan-3-ols
    blood-pressure
    3-hydroxyphenylacetic acid
    Saúde coletiva
    Química
    Nutrição
    Medicina veterinaria
    Medicina ii
    Medicina i
    Interdisciplinar
    Food science & technology
    Food science
    Farmacia
    Educação física
    Ciências biológicas ii
    Ciências biológicas i
    Ciências agrárias i
    Ciência de alimentos
    Biotecnología
    Biotechnology
    Astronomia / física
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