Author, as appears in the article.: Motevalizadeh E; Díaz-López A; Martín-Luján F; Basora J; Arija V

Department: Ciències Mèdiques Bàsiques Medicina i Cirurgia

URV's Author/s: Arija Val, Maria Victoria / Díaz López, Andres / Martín Lujan, Francisco Manuel / Motevalizadeh, Ehsan

Keywords: 1st trimester blood-pressure body-mass index eclipses gestational weight gain homa-ir hypertension lipid profile lipoprotein mediterranean diet obesity pregnancy women Cardiometabolic risk Eclipses Gestational weight gain Gestational weight-gain Homa-ir Pregnancy

Abstract: To examine the associations of sociodemographic, lifestyle, and clinical factors with cardiometabolic risk and each of its components during pregnancy in a pregnant population from Catalonia (Spain). A prospective cohort study of 265 healthy pregnant women (39 ± 5 years) in the first and third-trimesters. Sociodemographic, obstetric, anthropometric, lifestyle and dietary variables were collected, and blood samples were taken. The following cardiometabolic risk markers were evaluated: BMI, blood pressure, glucose, insulin, HOMA-IR, triglycerides, LDL, and HDL-cholesterol. From these, a cluster cardiometabolic risk (CCR)-z score was created by summating all z-scores (except insulin and DBP) computed for each risk factor. Data were analyzed using bivariate analysis and multivariable linear regression. In the multivariable models, the first-trimester CCRs was positively associated with overweight/obesity status (β: 3.54, 95%CI: 2.73, 4.36) but inversely related to the level of education (β: −1.04, 95%CI: −1.94, 0.14) and physical activity (PA) (β: −1.21, 95%CI: −2.24, −0.17). The association between overweight/obesity and CCR (β:1.91, 95%CI: 1.01, 2.82) persisted into the third-trimester, whereas insufficient GWG (β: −1.14, 95%CI: −1.98, −0.30) and higher social class (β: −2.28, 95%CI: −3.42, −1.13) were significantly associated with a lower CCRs. Starting pregnancy with normal weight, higher socioeconomic and educational levels, being a non-smoker, non-consumer of alcohol, and PA were protective factors against cardiovascular risk during pregnancy.

Thematic Areas: Biotecnología Ciência de alimentos Ciências agrárias i Ciências biológicas i Ciências biológicas ii Ciências biológicas iii Economia Educação física Enfermagem Engenharias ii Engenharias iv Farmacia Food science Interdisciplinar Medicina i Medicina ii Medicina iii Medicina veterinaria Nutrição Nutrition & dietetics Nutrition and dietetics Planejamento urbano e regional / demografia Psicología Química Saúde coletiva Zootecnia / recursos pesqueiros

licence for use: https://creativecommons.org/licenses/by/3.0/es/

Author's mail: ehsan.motevalizadeh@urv.cat victoria.arija@urv.cat andres.diaz@urv.cat paco.martin@urv.cat ehsan.motevalizadeh@urv.cat

Author identifier: 0000-0002-8692-7610 0000-0002-1758-0975 0000-0002-7500-5629 0000-0003-0359-3588 0000-0002-8692-7610

Record's date: 2023-04-08

Papper version: info:eu-repo/semantics/publishedVersion

Link to the original source: https://www.mdpi.com/2072-6643/15/5/1135

Papper original source: Nutrients. 15 (5):

APA: Motevalizadeh E; Díaz-López A; Martín-Luján F; Basora J; Arija V (2023). Prenatal Factors Associated with Maternal Cardiometabolic Risk Markers during Pregnancy: The ECLIPSES Study. Nutrients, 15(5), -. DOI: 10.3390/nu15051135

Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/

Article's DOI: 10.3390/nu15051135

Entity: Universitat Rovira i Virgili

Journal publication year: 2023

Publication Type: Journal Publications