Author, as appears in the article.: Iftimie, S; López-Azcona, AF; Lozano-Olmo, MJ; Naval-Ferrando, A; Domingo-Cortés, V; Castañé, H; Jiménez-Franco, A; Hernández-Aguilera, A; Guilarte, C; Riu, F; Camps, J; Joven, J; Castro, A
Department: Medicina i Cirurgia
URV's Author/s: Camps Andreu, Jorge / Castañé Vilafranca, Helena / Castro Salomó, Antoni / Iftimie Iftimie, Simona Mihaela / Jiménez Franco, Andrea / Joven Maried, Jorge / Riu Ferrando, Francisco Pedro
Keywords: Vaccines Vaccination Sars-cov-2 Pandemic Covid-19 Breakthrough infection
Abstract: SARS-CoV-2 infection in already-vaccinated individuals is still possible and may require hospitalization. The aim of the present study was to evaluate the clinical evolution of patients with COVID-19 admitted to a public hospital. The outcomes were assessed in relation to the predominant viral variant and the vaccination status. This retrospective study was performed on 1295 COVID-19-positive patients who attended a 352-bed university hospital between 2021 and 2022. Clinical variables and vaccination status were recorded. Of the patients, 799 had not been vaccinated (NV, 61.7%), 449 were partially vaccinated (PV, 34.7%), and 47 were completely vaccinated (CV, 3.6%). The mean age of the CV patients was significantly higher than that of PV and NV. Additionally, they had higher percentages of chronic diseases. The outcomes depended on age but not on vaccination status. There were 209 patients admitted during the Omicron-infection period, of whom 70 (33.5%) were NV, 135 (64.6%) were PV, and 4 (1.9%) were CV. In conclusion, correct vaccination greatly reduces the risk of acquiring severe COVID-19. Partial vaccination does not guarantee protection of the population. This highlights the need for continuous vaccination promotion with all recommended doses, while also investigating alternative treatments for those patients who do not respond to the vaccines.
Thematic Areas: Zootecnia / recursos pesqueiros Virology Saúde coletiva Química Medicina veterinaria Medicina ii Medicina i Interdisciplinar Infectious diseases Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Biotecnología Biodiversidade
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: franciscopedro.riu@urv.cat simonamihaela.iftime@urv.cat andrea.jimenez@urv.cat jorge.camps@urv.cat helena.castane@estudiants.urv.cat jorge.joven@urv.cat antoni.castro@urv.cat
Author identifier: 0000-0003-0714-8414 0000-0002-3165-3640 0000-0003-2749-4541 0000-0001-5441-6333
Record's date: 2024-08-03
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.mdpi.com/1999-4915/15/4/886
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Viruses-Basel. 15 (4): 886-
APA: Iftimie, S; López-Azcona, AF; Lozano-Olmo, MJ; Naval-Ferrando, A; Domingo-Cortés, V; Castañé, H; Jiménez-Franco, A; Hernández-Aguilera, A; Guilarte, C (2023). Retrospective Analysis of Vaccination Status and Predominant Viral Variants in Patients Hospitalized with COVID-19 in Reus, Spain. Viruses-Basel, 15(4), 886-. DOI: 10.3390/v15040886
Article's DOI: 10.3390/v15040886
Entity: Universitat Rovira i Virgili
Journal publication year: 2023
Publication Type: Journal Publications
Repositori URV