Author, as appears in the article.: Cruz-Rodríguez, J; Díaz-López, A; Canals-Sans, J; Arija, V
Department: Psicologia Ciències Mèdiques Bàsiques
URV's Author/s: Arija Val, Maria Victoria / Canals Sans, Josefa / Cruz Rodríguez, Josue / Díaz López, Andres
Keywords: Vitamin b12 deficiency Prenatal nutrition Pregnancy Infant neurodevelopment Eclipses study Cognitive function questionnaire prenatal nutrition pregnancy motor language infant neurodevelopment folate eclipses study dietary-intake deficiency children
Abstract: In this prospective cohort study of 434 mother-infant pairs from the ECLIPSES study, we examine the association between maternal vitamin B12 status at the beginning and end of pregnancy and the neurodevelopmental outcomes of infants 40 days after birth in a pregnant population from a Mediterranean region of northern Spain. Maternal vitamin B12 concentrations were determined in the first and third trimesters, and sociodemographic, nutritional, and psychological data were collected. At 40 days postpartum, the Bayley Scales of Infant Development-III (BSID-III, cognitive, language, and motor skills) were administered to the infants and several obstetrical data were recorded. In the multivariable models, medium maternal first-trimester vitamin B12 levels (312 to 408 pg/mL, tertile 2) were associated with better neonatal performance in the motor, gross motor, language, and cognitive skills with respect to tertile 1 (<312 pg/mL). The probability of obtaining a neonatal motor, gross motor, and receptive language score >75th percentile was significantly higher also in the tertile 2 group. In summary, good maternal vitamin B12 status in the early stage of pregnancy appears to be associated with better infant motor, language, and cognitive performance at 40 days postpartum.
Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: andres.diaz@urv.cat josue.cruz@estudiants.urv.cat josefa.canals@urv.cat victoria.arija@urv.cat
Author identifier: 0000-0002-7500-5629 0000-0002-6209-9558 0000-0002-1758-0975
Record's date: 2024-08-03
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.mdpi.com/2072-6643/15/6/1529
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Nutrients. 15 (6):
APA: Cruz-Rodríguez, J; Díaz-López, A; Canals-Sans, J; Arija, V (2023). Maternal Vitamin B12 Status during Pregnancy and Early Infant Neurodevelopment: The ECLIPSES Study. Nutrients, 15(6), -. DOI: 10.3390/nu15061529
Article's DOI: 10.3390/nu15061529
Entity: Universitat Rovira i Virgili
Journal publication year: 2023
Publication Type: Journal Publications