Author, as appears in the article.: Attard, M; Coral, D; Pedrol, E; Aguiló, M; Díaz, F; Mateos, X
Department: Química Física i Inorgànica
URV's Author/s: Aguiló Díaz, Magdalena / Díaz González, Francisco Manuel / Mateos Ferré, Xavier
Keywords: Microparticle manipulation Microfluidic devices Labs-on-a-chip Flow cytometry Circulating tumor-cells Cell sorting separation particle mixer microparticle manipulation micromixer microfluidic devices labs-on-a-chip flow cytometry channel cancer
Abstract: This work produces a unique microfluidic device that acts as a “lab on a chip,” conducting separation, mixing, and concentration of microparticles similar to that required by cell sorting flow cytometry applications. The passive two-dimensional device shows to be successful at separating polystyrene (PS) beads between 5 and 20 µm in diameter, mixing them with an external media, and concentrating them by 250% continuously with minimal sample preparation, while still being inexpensive, and effective. By implementing the microfluidic device, the processing steps are done within seconds due to its high throughput of 2 mL min−1, wherein different hydrodynamic phenomena such as Dean's forces, inertial lift forces, and enhanced diffusion are taken advantage of.
Thematic Areas: Química Nanoscience & nanotechnology Medicina ii Medicina i Materials science, multidisciplinary Materials science, characterization & testing Materials science (miscellaneous) Materials science (all) Materiais General materials science General chemistry Engineering, chemical Engenharias iv Engenharias ii Condensed matter physics Chemistry, physical Chemistry (miscellaneous) Chemistry (all) Astronomia / física
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: f.diaz@urv.cat magdalena.aguilo@urv.cat xavier.mateos@urv.cat
Author identifier: 0000-0003-4581-4967 0000-0001-6130-9579 0000-0003-1940-1990
Record's date: 2024-08-03
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://onlinelibrary.wiley.com/doi/full/10.1002/ppsc.202300038
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Particle & Particle Systems Characterization. 40 (9):
APA: Attard, M; Coral, D; Pedrol, E; Aguiló, M; Díaz, F; Mateos, X (2023). Microfluidic Device for the Manipulation of Microparticles for Flow Cytometry Application. Particle & Particle Systems Characterization, 40(9), -. DOI: 10.1002/ppsc.202300038
Article's DOI: 10.1002/ppsc.202300038
Entity: Universitat Rovira i Virgili
Journal publication year: 2023
Publication Type: Journal Publications
Repositori URV