Author, as appears in the article.: Aristei C; Kaidar-Person O; Boersma L; Leonardi MC; Offersen B; Franco P; Arenas M; Bourgier C; Pfeffer R; Kouloulias V; Bölükbaşı Y; Meattini I; Coles C; Luis AM; Masiello V; Palumbo I; Morganti AG; Perrucci E; Tombolini V; Krengli M; Marazzi F; Trigo L; Borghesi S; Ciabattoni A; Ratoša I; Valentini V; Poortmans P
Department: Ciències Mèdiques Bàsiques
URV's Author/s: Arenas Prat, Meritxell
Keywords: Re-irradiation in relapsed patients Radiation therapy Immunotherapy Combined modality treatment Breast cancer
Abstract: The present white paper, referring to the 4th Assisi Think Tank Meeting on breast cancer, reviews state-of-the-art data, on-going studies and research proposals. < 70% agreement in an online questionnaire identified the following clinical challenges: 1: Nodal RT in patients who have a) 1-2 positive sentinel nodes without ALND (axillary lymph node dissection); b) cN1 disease transformed into ypN0 by primary systemic therapy and c) 1-3 positive nodes after mastectomy and ALND. 2. The optimal combination of RT and immunotherapy (IT), patient selection, IT-RT timing, and RT optimal dose, fractionation and target volume. Most experts agreed that RT- IT combination does not enhance toxicity. 3: Re-irradiation for local relapse converged on the use of partial breast irradiation after second breast conserving surgery. Hyperthermia aroused support but is not widely available. Further studies are required to finetune best practice, especially given the increasing use of re-irradiation.Copyright © 2023. Published by Elsevier B.V.
Thematic Areas: Saúde coletiva Oncology Odontología Medicina ii Medicina i Hematology Geriatrics and gerontology Ciências biológicas i Biotecnología
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: meritxell.arenas@urv.cat
Author identifier: 0000-0003-0815-2570
Record's date: 2024-08-03
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.sciencedirect.com/science/article/pii/S1040842823001233?via%3Dihub
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Critical Reviews In Oncology Hematology. 187 104035-104035
APA: Aristei C; Kaidar-Person O; Boersma L; Leonardi MC; Offersen B; Franco P; Arenas M; Bourgier C; Pfeffer R; Kouloulias V; Bölükbaşı Y; Meattini I; Cole (2023). The 2022 Assisi Think Tank Meeting: White paper on optimising radiation therapy for breast cancer. Critical Reviews In Oncology Hematology, 187(), 104035-104035. DOI: 10.1016/j.critrevonc.2023.104035
Article's DOI: 10.1016/j.critrevonc.2023.104035
Entity: Universitat Rovira i Virgili
Journal publication year: 2023
Publication Type: Journal Publications
Repositori URV