Facile Synthesis of Vanadium Oxide/Carbon Spheres-Doped Nickel Oxide Functioned as a Nanocatalyst and Bactericidal Behavior with Molecular Docking Analysis

Identifier:  imarina:9324046

Handle: https://hdl.handle.net/20.500.11797/imarina9324046

Authors:  Baz, S; Ikram, M; Haider, A; Shahzadi, A; Ul-Hamid, A; Nabgan, W; Haider, J; Imran, M; Alshahrani, T; Medina, F; Imran, M

Abstract:
Vanadium oxide (V2O5) and carbonspheres(Cs)-doped NiO2 nanostructures (NSs) were prepared usingthe co-precipitation approach. Several spectroscopic and microscopictechniques, including X-ray diffraction (XRD), UV-vis, FTIR,TEM, and HR-TEM investigations, were used to describe the as-synthesizedNSs. The XRD pattern exhibited the hexagonal structure, and the crystallitesize of pristine and doped NSs was calculated as 29.3, 32.8, 25.79,and 45.19 nm, respectively. The control sample (NiO2) showedmaximum absorption at 330 nm, and upon doping, a redshift was observed,leading to decreased band gap energy from 3.75 to 3.59 eV. TEM ofNiO(2) shows agglomerated nonuniform nanorods exhibited withvarious nanoparticles without a specific orientation; a higher agglomerationwas observed upon doping. The (4 wt %) V2O5/Cs-dopedNiO(2) NSs served as superior catalysts with a 94.21% MBreduction in acidic media. The significant antibacterial efficacywas estimated against Escherichia coli by measuring the zone of inhibition (3.75 mm). Besidestheir bactericidal analysis, V2O5/Cs-doped NiO2 was shown to have a binding score of 6.37 for dihydrofolatereductase and a binding score of 4.31 for dihydropteroate synthasein an in silico docking study of E. coli.