Author, as appears in the article.: Andhalkar, Vaibhav Vilas; Foong, Shin Ying; Kee, Seng Hon; Lam, Su Shiung; Chan, Yi Herng; Djellabi, Ridha; Bhubalan, Kesaven; Medina, Francesc; Constanti, Magdalena
Department: Enginyeria Química
URV's Author/s: Andhalkar, Vaibhav Vilas / Constantí Garriga, Magdalena / Djellabi, Ridha / Medina Cabello, Francisco
Keywords: Techno-economic analysis Polyhydroxyalkanoates Microbial cell factories Life cycle assessment Integrated biorefinery waste techno-economic analysis strategies polyhydroxyalkanoates pha biopolyesters mixed-culture life cycle assessment fermentation escherichia-coli coproduction challenges biohydrogen production
Abstract: To support and move toward a sustainable bioeconomy, the production of polyhydroxyalkanoates (PHAs) using renewable biomass has acquired more attention. However, expensive biomass pretreatment and low yield of PHAs pose significant disadvantages in its large-scale production. To overcome such limitations, the most recent advances in metabolic engineering strategies used to develop high-performance strains that are leading to a new manufacturing concept converting biomass to PHAs with co-products such as amino acids, proteins, biohydrogen, biosurfactants, and various fine chemicals are critically summarized. This review article presents a comprehensive roadmap that highlights the integrated biorefinery strategies, lifecycle analysis, and techno-economic assessment for sustainable and economic PHAs production. Finally, current and future challenges that must be addressed to transfer this technology to real-world applications are reviewed.
Thematic Areas: Química Polymers and plastics Polymer science Organic chemistry Materials science, multidisciplinary Materials chemistry Materiais General chemical engineering Engenharias ii Engenharias i Ciências agrárias i Ciência de alimentos Chemical engineering (miscellaneous) Chemical engineering (all) Biotecnología Astronomia / física
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: vaibhavvilas.andhalkar@estudiants.urv.cat vaibhavvilas.andhalkar@estudiants.urv.cat magdalena.constanti@urv.cat francesc.medina@urv.cat
Author identifier: 0000-0003-4686-0762 0000-0003-4686-0762 0000-0002-3547-4199 0000-0002-3111-1542
Record's date: 2024-10-12
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://onlinelibrary.wiley.com/doi/full/10.1002/mame.202300100
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Macromolecular Materials And Engineering. 308 (11):
APA: Andhalkar, Vaibhav Vilas; Foong, Shin Ying; Kee, Seng Hon; Lam, Su Shiung; Chan, Yi Herng; Djellabi, Ridha; Bhubalan, Kesaven; Medina, Francesc; Const (2023). Integrated Biorefinery Design with Techno-Economic and Life Cycle Assessment Tools in Polyhydroxyalkanoates Processing. Macromolecular Materials And Engineering, 308(11), -. DOI: 10.1002/mame.202300100
Article's DOI: 10.1002/mame.202300100
Entity: Universitat Rovira i Virgili
Journal publication year: 2023
Publication Type: Journal Publications
Repositori URV