Author, as appears in the article.: Pazos-Perez, Nicolas; Guerrini, Luca
Department: Química Física i Inorgànica
URV's Author/s: Guerrini, Luca / Pazos Pérez, Nicolás Carlos
Keywords: Wilson's disease Surface-enhanced raman spectroscopy Plasmonic nanoparticles Metal-organic frameworks (mofs) Metal ions Detection
Abstract: Nanosensors based on surface-enhanced Raman spectroscopy (SERS) have emerged as a class of promising optical tools for the ultrasensitive quantification of metal ions of environmental and biological interest. A central bottleneck in this field is the availability of suitable surface receptors able to convert the selective binding with these vibrationless analytes into measurable SERS signals. In this work, we tackle this issue by employing a hybrid substrate comprising a highly SERS-active plasmonic core and a ZIF-8 metal-organic framework (MOF) shell. The ZIF-8 shell firmly captures aromatic receptors close to the plasmonic structure regardless of their intrinsic affinity for the metallic surface and without altering their ability to coordinate metal ions. Furthermore, it imparts molecular sieving abilities enabling the direct use of the SERS sensing platform in complex media such as biological fluids. This was demonstrated by using different classes of chromogenic reagents (bathocuproine, a 2,6':2′,2″-terpyridine derivative, and Arsenazo III) which were exploited for the SERS detection of both transition and alkaline earth metal ions (i.e., divalent copper, cobalt and calcium ions). Notably, we successfully applied this approach for the detection of Cu(II) in untreated urine samples for Wilson's disease diagnosis. Overall, we believe this class of multifunctional hybrid substrates will serve as a valuable material for expanding the applicability of SERS spectroscopy in real-life environmental and biomedical metal ions analysis.
Thematic Areas: Zootecnia / recursos pesqueiros Spectroscopy Saúde coletiva Química Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Geociências General medicine General chemistry Farmacia Ensino Engenharias iv Engenharias iii Engenharias ii Engenharias i Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Chemistry, analytical Chemistry (miscellaneous) Biotecnología Biodiversidade Biochemistry Astronomia / física Analytical chemistry Administração pública e de empresas, ciências contábeis e turismo
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: luca.guerrini@urv.cat nicolas.pazos@urv.cat
Author identifier: 0000-0002-2925-1562 0000-0002-2326-4231
Record's date: 2024-11-02
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.sciencedirect.com/science/article/pii/S0039914023006926
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Talanta. 266 (Pt 1): 124941-
APA: Pazos-Perez, Nicolas; Guerrini, Luca (2024). Extending the range of metal ions SERS detection using hybrid plasmonic/ZIF-8 particles. Talanta, 266(Pt 1), 124941-. DOI: 10.1016/j.talanta.2023.124941
Article's DOI: 10.1016/j.talanta.2023.124941
Entity: Universitat Rovira i Virgili
Journal publication year: 2024
Publication Type: Journal Publications
Repositori URV