Articles producció científica> Ciències Mèdiques Bàsiques

Shock waves as treatment of mouse myofascial trigger points

  • Identification data

    Identifier: imarina:9326078
  • Authors:

    Monclús, P
    Bosque, M
    Margalef, R
    Colomina, MT
    Valderrama-Canales, FJ
    Just, L
    Santafé, MM
  • Others:

    Author, as appears in the article.: Monclús, P; Bosque, M; Margalef, R; Colomina, MT; Valderrama-Canales, FJ; Just, L; Santafé, MM
    Department: Ciències Mèdiques Bàsiques
    URV's Author/s: Bosque Alberich, Marc / Colomina Fosch, Maria Teresa / Just Borràs, Laia / Margalef Pérez, Joan Ramon / Santafé Martínez, Manuel / Valderrama Canales, Francisco José
    Keywords: Therapy Shock waves Pain syndrome Neostigmine Myofascial trigger point Myofascial pain syndrome Management
    Abstract: Introduction An abnormal increase in spontaneous neurotransmission can induce subsynaptic knots in the myocyte called myofascial trigger points. The treatment of choice is to destroy these trigger points by inserting needles. However, 10% of the population has a phobia of needles, blood, or injuries. Therefore, the objective of this study is to verify the usefulness of shock waves in the treatment of myofascial trigger points.Methods Two groups of mice have been developed for this: healthy muscles treated with shock waves; trigger points affected muscles artificially generated with neostigmine and subsequently treated with shock waves. Muscles were stained with methylene blue, PAS-Alcian Blue, and labeling the axons with fluorescein and the acetylcholine receptors with rhodamine. Using intracellular recording the frequency of miniature endplate potentials (mEPPs) was recorded and endplate noise was recorded with electromyography.Results No healthy muscles treated with shock waves showed injury. Twitch knots in mice previously treated with neostigmine disappeared after shock wave treatment. Several motor axonal branches were retracted. On the other hand, shock wave treatment reduces the frequency of mEPPs and the number of areas with endplate noise.Discussion Shock waves seem to be a suitable treatment for myofascial trigger points. In the present study, with a single session of shock waves, very relevant results have been obtained, both functional (normalization of spontaneous neurotransmission) and morphological (disappearance of myofascial trigger points). Patients with a phobia of needles, blood, or injuries who cannot benefit from dry needling may turn to noninvasive radial shock wave treatment.
    Thematic Areas: Saúde coletiva Psicología Medicina iii Medicina ii Medicina i Interdisciplinar General medicine Farmacia Educação física Clinical neurology Ciências biológicas ii Anesthesiology and pain medicine Anesthesiology
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: joanramon.margalef@urv.cat laia.just@urv.cat joanramon.margalef@urv.cat laia.just@urv.cat manuel.santafe@urv.cat mariateresa.colomina@urv.cat
    Author identifier: 0000-0003-0473-3730 0000-0003-0473-3730 0000-0002-5462-5108 0000-0002-5619-4874
    Record's date: 2024-07-20
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://onlinelibrary.wiley.com/doi/epdf/10.1111/papr.13237
    Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Pain Practice. 23 (7): 724-733
    APA: Monclús, P; Bosque, M; Margalef, R; Colomina, MT; Valderrama-Canales, FJ; Just, L; Santafé, MM (2023). Shock waves as treatment of mouse myofascial trigger points. Pain Practice, 23(7), 724-733. DOI: 10.1111/papr.13237
    Article's DOI: 10.1111/papr.13237
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2023
    Publication Type: Journal Publications
  • Keywords:

    Anesthesiology,Anesthesiology and Pain Medicine,Clinical Neurology
    Therapy
    Shock waves
    Pain syndrome
    Neostigmine
    Myofascial trigger point
    Myofascial pain syndrome
    Management
    Saúde coletiva
    Psicología
    Medicina iii
    Medicina ii
    Medicina i
    Interdisciplinar
    General medicine
    Farmacia
    Educação física
    Clinical neurology
    Ciências biológicas ii
    Anesthesiology and pain medicine
    Anesthesiology
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