Author, as appears in the article.: Moltó-Balado, P; Reverté-Villarroya, S; Monclús-Arasa, C; Balado-Albiol, MT; Baset-Martínez, S; Carot-Domenech, J; Clua-Espuny, JL
Department: Infermeria
URV's Author/s: REVERTÉ REVERTÉ, SANDRA / Reverté Villarroya, Silvia
Keywords: Vascular events Score Risk-atrial fibrillation Risk Primary health care Outcomes Mortality Major outcomes Major adverse cardiovascular events (mace) Heart failure Covid-19 Chronic kidney-disease Atrial fibrillation
Abstract: Background: Atrial fibrillation (AF) is a common cardiac arrhythmia that is associated with an increased risk of major adverse cardiovascular events (MACE). The main goal was to analyze the links and associations between AF and MACE. Methods: A multicenter, observational, retrospective, community-based study of a cohort (n = 40,297) of the general population aged 65-95 years between 1 January 2015 and 31 December 2021 without a previous diagnosis of AF or MACE in the Primary Care setting. Results: 2574 people (6.39%) developed a first AF event, resulting in an overall incidence of 8.9/1000 people-years [CI95% 8.6-9.2]. The incidence of MACE among those with AF was 75.1/1000 people-years [CI95% 70.8-79.5], whereas among those without AF, it was 20.6/1000 people-years [CI 95% 20.2-21.1], resulting in a rate ratio of 3.65 [CI 95% 3.43-3.88, p < 0.001]. Besides, the incidence of HF with AF was 40.1 people-years [CI 95% 37.1-43.2], while in the group without AF, it was 8.3 people-years [CI 95% 7.9-8.6, p < 0.001], with a rate ratio of 4.85 [CI 95% 4.45-55.3, p < 0.001]. Before an AF diagnosis, there is already a higher risk of chronic kidney disease, ischemic cardiopathy, and peripheral artery disease. A higher risk of poor nutritional status was detected among those with MACE (49.7% vs. 26.6%, p < 0.001). Conclusions: AF diagnosis increases the incidence of heart failure fourfold. Additional information is required to establish the connection between AF, major adverse cardiovascular events, and nutritional status.
Thematic Areas: Pharmacology & pharmacy Medicine, research & experimental Medicine (miscellaneous) General biochemistry,genetics and molecular biology Ciencias sociales Biochemistry, genetics and molecular biology (miscellaneous) Biochemistry, genetics and molecular biology (all) Biochemistry & molecular biology
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: silvia.reverte@urv.cat
Author identifier: 0000-0002-2052-9978
Record's date: 2024-09-28
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.mdpi.com/2227-9059/11/7/1825
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Biomedicines. 11 (7):
APA: Moltó-Balado, P; Reverté-Villarroya, S; Monclús-Arasa, C; Balado-Albiol, MT; Baset-Martínez, S; Carot-Domenech, J; Clua-Espuny, JL (2023). Heart Failure and Major Adverse Cardiovascular Events in Atrial Fibrillation Patients: A Retrospective Primary Care Cohort Study. Biomedicines, 11(7), -. DOI: 10.3390/biomedicines11071825
Article's DOI: 10.3390/biomedicines11071825
Entity: Universitat Rovira i Virgili
Journal publication year: 2023
Publication Type: Journal Publications
Repositori URV