Articles producció científica> Enginyeria Química

Peptide-Based Vaccine against Breast Cancer: Recent Advances and Prospects

  • Identification data

    Identifier: imarina:9326639
  • Authors:

    Nordin ML
    Azemi AK
    Nordin AH
    Nabgan W
    Ng PY
    Yusoff K
    Abu N
    Lim KP
    Zakaria ZA
    Ismail N
    Azmi F
  • Others:

    Author, as appears in the article.: Nordin ML; Azemi AK; Nordin AH; Nabgan W; Ng PY; Yusoff K; Abu N; Lim KP; Zakaria ZA; Ismail N; Azmi F
    Department: Enginyeria Química
    URV's Author/s: Nabgan, Walid
    Keywords: Peptide-based vaccine Nanoparticle Metastasis Immunotherapy Breast cancer
    Abstract: Breast cancer is considered the second-leading cancer after lung cancer and is the most prevalent cancer among women globally. Currently, cancer immunotherapy via vaccine has gained great attention due to specific and targeted immune cell activity that creates a potent immune response, thus providing long-lasting protection against the disease. Despite peptides being very susceptible to enzymatic degradation and poor immunogenicity, they can be easily customized with selected epitopes to induce a specific immune response and particulate with carriers to improve their delivery and thus overcome their weaknesses. With advances in nanotechnology, the peptide-based vaccine could incorporate other components, thereby modulating the immune system response against breast cancer. Considering that peptide-based vaccines seem to show remarkably promising outcomes against cancer, this review focuses on and provides a specific view of peptide-based vaccines used against breast cancer. Here, we discuss the benefits associated with a peptide-based vaccine, which can be a mainstay in the prevention and recurrence of breast cancer. Additionally, we also report the results of recent trials as well as plausible prospects for nanotechnology against breast cancer.
    Thematic Areas: Saúde coletiva Química Pharmacology & pharmacy Pharmaceutical science Molecular medicine Medicina ii Interdisciplinar Farmacia Drug discovery Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Chemistry, medicinal Biotecnología Biodiversidade
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: walid.nabgan@urv.cat
    Author identifier: 0000-0001-9901-862X
    Record's date: 2023-08-19
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://www.mdpi.com/1424-8247/16/7/923
    Papper original source: Pharmaceuticals. 16 (7):
    APA: Nordin ML; Azemi AK; Nordin AH; Nabgan W; Ng PY; Yusoff K; Abu N; Lim KP; Zakaria ZA; Ismail N; Azmi F (2023). Peptide-Based Vaccine against Breast Cancer: Recent Advances and Prospects. Pharmaceuticals, 16(7), -. DOI: 10.3390/ph16070923
    Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
    Article's DOI: 10.3390/ph16070923
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2023
    Publication Type: Journal Publications
  • Keywords:

    Chemistry, Medicinal,Drug Discovery,Molecular Medicine,Pharmaceutical Science,Pharmacology & Pharmacy
    Peptide-based vaccine
    Nanoparticle
    Metastasis
    Immunotherapy
    Breast cancer
    Saúde coletiva
    Química
    Pharmacology & pharmacy
    Pharmaceutical science
    Molecular medicine
    Medicina ii
    Interdisciplinar
    Farmacia
    Drug discovery
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Chemistry, medicinal
    Biotecnología
    Biodiversidade
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