Author, as appears in the article.: Shyam, S; Gómez-Martínez, C; Paz-Graniel, I; Gaforio, JJ; Martínez-González, MA; Corella, D; Fitó, M; Martínez, JA; Alonso-Gómez, AM; Wärnberg, J; Vioque, J; Romaguera, D; López-Miranda, J; Estruch, R; Tinahones, FJ; Santos-Lozano, JM; Serra-Majem, JL; Bueno-Cavanillas, A; Tur, JA; Sánchez, VM; Pintó, X; Ramos, M; Vidal, J; Alcarria, MM; Daimiel, L; Ros, E; Fernandez-Aranda, F; Nishi, SK; Regata, OG; Toledo, E; Sorli, JV; Castañer, O; Garcia-Rios, A; Valls-Enguix, R; Perez-Farinos, N; Zulet, MA; Rayó-Gago, E; Casas, R; Rivera-Izquierdo, M; Tojal-Sierra, L; Damas-Fuentes, M; Buil-Cosiales, P; Fernández-Carrion, R; Goday, A; Peña-Orihuela, PJ; Compañ-Gabucio, L; Diez-Espino, J; Tello, S; González-Pinto, A; de la O, V; Delgado-Rodríguez, M; Babio, N; Salas-Salvadó, J
Department: Bioquímica i Biotecnologia
URV's Author/s: Alkhoury, Nadine / Babio Sánchez, Nancy Elvira / Nishi, Stephanie Kimiko / Paz Graniel, Indira del Socorro / Salas Salvadó, Jorge / Shyam, Sangeetha
Keywords: Sars-cov-2 Predimed-plus Overweight Older adults Obesity Metabolic syndrome Humans Female Depression Covid-19 Aged sars-cov-2 predimed-plus older adults depression
Abstract: The coronavirus disease 2019 (COVID-19) has serious physiological and psychological consequences. The long-term (>12 weeks post-infection) impact of COVID-19 on mental health, specifically in older adults, is unclear. We longitudinally assessed the association of COVID-19 with depression symptomatology in community-dwelling older adults with metabolic syndrome within the framework of the PREDIMED-Plus cohort.Participants (n = 5486) aged 55-75 years were included in this longitudinal cohort. COVID-19 status (positive/negative) determined by tests (e.g. polymerase chain reaction severe acute respiratory syndrome coronavirus 2, IgG) was confirmed via event adjudication (410 cases). Pre- and post-COVID-19 depressive symptomatology was ascertained from annual assessments conducted using a validated 21-item Spanish Beck Depression Inventory-II (BDI-II). Multivariable linear and logistic regression models assessed the association between COVID-19 and depression symptomatology.COVID-19 in older adults was associated with higher post-COVID-19 BDI-II scores measured at a median (interquartile range) of 29 (15-40) weeks post-infection [fully adjusted β = 0.65 points, 95% confidence interval (CI) 0.15-1.15; p = 0.011]. This association was particularly prominent in women (β = 1.38 points, 95% CI 0.44-2.33, p = 0.004). COVID-19 was associated with 62% increased odds of elevated depression risk (BDI-II ≥ 14) post-COVID-19 when adjusted for confounders (odds ratio; 95% CI 1.13-2.30, p = 0.008).COVID-19 was associated with long-term depression risk in older adults with overweight/obesity and metabolic syndrome, particularly in women. Thus, long-term evaluations of the impact of COVID-19 on mental health and preventive public health initiatives are warranted in older adults.
Thematic Areas: Saúde coletiva Psychology, clinical Psychology Psychiatry and mental health Psychiatry Psicología Medicina ii Medicina i Interdisciplinar General medicine Educação Ciencias sociales Ciências biológicas ii Ciências biológicas i Applied psychology Antropologia / arqueologia
Author's mail: sangeetha.shyam@urv.cat stephanie.nishi@urv.cat indiradelsocorro.paz@urv.cat nancy.babio@urv.cat jordi.salas@urv.cat indiradelsocorro.paz@urv.cat nadine.alkhoury@estudiants.urv.cat nadine.alkhoury@estudiants.urv.cat nadine.alkhoury@estudiants.urv.cat nadine.alkhoury@estudiants.urv.cat
Author identifier: 0000-0002-3204-6877 0000-0003-3527-5277 0000-0003-2700-7459 0000-0002-3204-6877
Record's date: 2024-06-28
Papper version: info:eu-repo/semantics/acceptedVersion
Link to the original source: https://www.cambridge.org/core/journals/psychological-medicine/article/abs/coronavirus-disease-2019-is-associated-with-longterm-depressive-symptoms-in-spanish-older-adults-with-overweightobesity-and-metabolic-syndrome/D25A87FFCF3AF07997BA3902E68FA881#access-block
Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Psychological Medicine. 54 (3): 1-11
APA: Shyam, S; Gómez-Martínez, C; Paz-Graniel, I; Gaforio, JJ; Martínez-González, MA; Corella, D; Fitó, M; Martínez, JA; Alonso-Gómez, AM; Wärnberg, J; Vio (2024). Coronavirus disease 2019 is associated with long-term depressive symptoms in Spanish older adults with overweight/obesity and metabolic syndrome. Psychological Medicine, 54(3), 1-11. DOI: 10.1017/S0033291723002313
Article's DOI: 10.1017/S0033291723002313
Entity: Universitat Rovira i Virgili
Journal publication year: 2024
Publication Type: Journal Publications
Repositori URV