Author, as appears in the article.: González, N; Pàmies, C; Martinez, P; Martí, L; Domingo, JL; Nadal, M; Marquès, M
Department: Ciències Mèdiques Bàsiques
URV's Author/s: Domingo Roig, José Luis / Gonzalez Paradell, Nieves / Marquès Bueno, Montserrat / Martínez Cánovas, Paula / Nadal Lomas, Martí
Keywords: Urine analysis Pesticides Organic food products Dietary exposure Dialkyl phosphates Dialkyl phosphate metabolites Biomonitoring urine analysis urinary concentrations risk residues reduction pesticides pesticide metabolites parameters organic food products exposure dietary exposure dialkyl phosphates
Abstract: Pesticides are a group of organic compounds used to control weeds or insect infestations in agriculture. Diet is the major route of human exposure to these compounds, which can cause serious health problems, even when the intake occurs at low concentrations. Hence, the consumption of organic food is an appropriate strategy to minimize the exposure to pesticides. A prospective, randomized study was conducted to assess the impact of an organic dietary intervention on the levels of urinary dialkyl phosphates (DAP). A screening of 204 pesticides was also carried out in order to confirm the absence of these compounds in organic food. The analytical results showed that only 20 of the 204 pesticides (9.8 %) had concentrations above the limit of quantification in one or more samples of the organic food consumed by the participants. It is substantially lower than the levels of pesticides found in other studies analysing conventional food, confirming the diet as suitable for the organic dietary intervention. A general reduction of most DAP metabolites in urine was found, being significant (p < 0.05) the decrease of dimethyl phosphate (DMP) (0.49 µg/g creatinine in Day 1 vs. 0.062 µg/g creatinine in Day 6), dimethyl thiophosphate (DMTP) (0.49 µg/g creatinine in Day 1 vs. 0.093 µg/g creatinine in Day 6) and diethyl phosphate (DEP) (0.28 µg/g creatinine in Day 1 vs. 0.12 µg/g creatinine in Day 6). In addition, the molar score for the total dimethyl DAP (ΣMP) and total dialkyl phosphate (ΣDAP) also showed significant differences after changing a conventional diet by an organic diet, being reduced from 0.008 µmol/g to 0.002 µmol/g for ΣMP and from 0.012 µmol/g to 0.003 µmol/g for ΣDAP. To the best of our knowledge, this is the first study that evaluates both the impact of an organic diet in the exposure to DAP and the levels of 204 pesticides in the organic food provided to the participants. In summary, the consumption of organic products decreases the dietary intake of pesticides, thus reducing also the potential adverse effects on human health.Copyright © 2023 The Author(s). Published by Elsevier Ltd.. All rights reserved.
Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Odontología Nutrição Medicina veterinaria Medicina ii Medicina i Materiais Matemática / probabilidade e estatística Interdisciplinar Food science & technology Food science Farmacia Ensino Engenharias iv Engenharias iii Engenharias ii Engenharias i Educação Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Biotecnología Biodiversidade Astronomia / física Administração pública e de empresas, ciências contábeis e turismo
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: paula.martinez@urv.cat joseluis.domingo@urv.cat marti.nadal@urv.cat montserrat.marques@urv.cat nieves.gonzalez@urv.cat
Author identifier: 0000-0001-6647-9470 0000-0002-0217-4827 0000-0001-6302-8578 0000-0003-4134-016X
Record's date: 2024-02-10
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.sciencedirect.com/science/article/pii/S0963996923008992?via%3Dihub
Papper original source: Food Research International. 173 (Pt 1): 113354-113354
APA: González, N; Pàmies, C; Martinez, P; Martí, L; Domingo, JL; Nadal, M; Marquès, M (2023). Effects of an organic diet intervention on the levels of organophosphorus metabolites in an adult cohort. Food Research International, 173(Pt 1), 113354-113354. DOI: 10.1016/j.foodres.2023.113354
Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
Article's DOI: 10.1016/j.foodres.2023.113354
Entity: Universitat Rovira i Virgili
Journal publication year: 2023
Publication Type: Journal Publications
Repositori URV