Articles producció científica> Ciències Mèdiques Bàsiques

Treatment plan complexity does not predict IROC Houston anthropomorphic head and neck phantom performance

  • Identification data

    Identifier: imarina:9334288
  • Authors:

    Glenn, MC
    Hernandez, V
    Saez, J
    Followill, DS
    Howell, RM
    Pollard-Larkin, JM
    Zhou, SH
    Kry, SF
    Physics In Medicine And Biology
    10.1088/1361-6560/aae29e
    Physics In Medicine And Biology. 63 (20): 205015-
  • Others:

    Author, as appears in the article.: Glenn, MC; Hernandez, V; Saez, J; Followill, DS; Howell, RM; Pollard-Larkin, JM; Zhou, SH; Kry, SF
    Department: Ciències Mèdiques Bàsiques
    URV's Author/s: Hernandez Masgrau, Victor
    Keywords: Radiotherapy, intensity-modulated Radiotherapy planning, computer-assisted Radiotherapy dosage Radiometry Quality-assurance Quality assurance Plan complexity Phantoms, imaging Particle accelerators Neck Modulation Metrics Iroc Intensity-modulated radiotherapy Index Imrt qa Humans Head Dosimetry Credentialing Beam Anthropomorphic phantom
    Abstract: Previous works indicate that intensity-modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) plans that are highly complex may produce more errors in dose calculation and treatment delivery. Multiple complexity metrics have been proposed and associated with IMRT QA results, but their relationships with plan performance using in situ dose measurements have not been thoroughly investigated. This study aimed to evaluate the relationships between IMRT treatment plan complexity and anthropomorphic phantom performance in order to assess the extent to which plan complexity is related to dosimetric performance in the IROC phantom credentialing program. Sixteen complexity metrics, including the modulation complexity score (MCS), several modulation indices, and total monitor units (MU) delivered, were evaluated for 343 head and neck phantom irradiations, comprising both IMRT (step-and-shoot and sliding window techniques) and VMAT. Spearman's correlations were used to explore the relationship between complexity and plan performance, as measured by the dosimetric differences between the treatment planning system (TPS) and thermoluminescent dosimeter (TLD) measurement, as well as film gamma analysis. Relationships were likewise determined for several combinations of subpopulations, based on the linear accelerator model, TPS used, and delivery modality. Evaluation of the complexity metrics presented here yielded no significant relationships (p > 0.01, Bonferroni-corrected) and all correlations were weak (less than +/- 0.30). These results indicate that complexity metrics have limited predictive utility in assessing plan performance in multi-institutional comparisons of IMRT plans. Other factors affecting plan accuracy, such as dosimetric modeling or multileaf collimator (MLC) performance, should be investigated to determine a more probable cause for dose delivery errors.
    Thematic Areas: Saúde coletiva Radiology, nuclear medicine and imaging Radiology, nuclear medicine & medical imaging Radiological and ultrasound technology Psicología Odontología Medicina ii Medicina i Matemática / probabilidade e estatística Interdisciplinar General medicine Engineering, biomedical Engenharias iv Engenharias iii Engenharias ii Ciências biológicas ii Ciências biológicas i Ciência da computação Astronomia / física
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: victor.hernandez@urv.cat
    Author identifier: 0000-0003-3770-8486
    Record's date: 2024-07-20
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://iopscience.iop.org/article/10.1088/1361-6560/aae29e
    Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Physics In Medicine And Biology. 63 (20): 205015-
    APA: Glenn, MC; Hernandez, V; Saez, J; Followill, DS; Howell, RM; Pollard-Larkin, JM; Zhou, SH; Kry, SF (2018). Treatment plan complexity does not predict IROC Houston anthropomorphic head and neck phantom performance. Physics In Medicine And Biology, 63(20), 205015-. DOI: 10.1088/1361-6560/aae29e
    Article's DOI: 10.1088/1361-6560/aae29e
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2018
    Publication Type: Journal Publications
  • Keywords:

    Engineering, Biomedical,Radiological and Ultrasound Technology,Radiology, Nuclear Medicine & Medical Imaging,Radiology, Nuclear Medicine and Imaging
    Radiotherapy, intensity-modulated
    Radiotherapy planning, computer-assisted
    Radiotherapy dosage
    Radiometry
    Quality-assurance
    Quality assurance
    Plan complexity
    Phantoms, imaging
    Particle accelerators
    Neck
    Modulation
    Metrics
    Iroc
    Intensity-modulated radiotherapy
    Index
    Imrt qa
    Humans
    Head
    Dosimetry
    Credentialing
    Beam
    Anthropomorphic phantom
    Saúde coletiva
    Radiology, nuclear medicine and imaging
    Radiology, nuclear medicine & medical imaging
    Radiological and ultrasound technology
    Psicología
    Odontología
    Medicina ii
    Medicina i
    Matemática / probabilidade e estatística
    Interdisciplinar
    General medicine
    Engineering, biomedical
    Engenharias iv
    Engenharias iii
    Engenharias ii
    Ciências biológicas ii
    Ciências biológicas i
    Ciência da computação
    Astronomia / física
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