Articles producció científica> Bioquímica i Biotecnologia

Association between type 2 diabetes and depressive symptoms after a 1-year follow-up in an older adult Mediterranean population

  • Identification data

    Identifier: imarina:9334356
    Authors:
    Baenas, ICamacho-Barcia, LGranero, RRazquin, CCorella, DGomez-Martinez, CCastaner-Nino, OMartinez, JAAlonso-Gomez, AMWaernberg, JVioque, JRomaguera, DLopez-Miranda, JEstruch, RTinahones, FJLapetra, JSerra-Majem, JLCano-Ibanez, NTur, JAMartin-Sanchez, VPinto, XGaforio, JJMatia-Martin, PVidal, JVazquez, CDaimiel, LRos, EJimenez-Murcia, SDalsgaard, SGarcia-Arellano, ABabio, NSorli, JVLassale, CGarcia-de-la-Hera, MGomez-Garcia, EZulet, MAKonieczna, JMartin-Pelaez, STojal-Sierra, LBasterra-Gortari, FJde las Heras-delgado, SPortoles, OMunoz-Perez, MAArenas-Larriva, APCompan-Gabucio, LEguaras, SShyam, SFito, MBanos, RMSalas-Salvado, JFernandez-Aranda, F
    Abstract:
    To examine the cross-sectional association between baseline depressive symptoms and the presence of type 2 diabetes (T2D), and its association with glycated hemoglobin (HbA1c) and other metabolic variables, and the prospective association of depressive symptoms and HbA1c after 1 year of follow-up.n = 6224 Mediterranean older adults with overweight/obesity and metabolic syndrome (48% females, mean age 64.9 ± 4.9 years) were evaluated in the framework of the PREDIMED-Plus study cohort. Depressive symptoms were assessed using the Beck Depression Inventory-II and HbA1c was used to measure metabolic control.The presence of T2D increased the likelihood of higher levels of depressive symptoms (χ2 = 15.84, p = 0.001). Polynomial contrast revealed a positive linear relationship (χ2 = 13.49, p = 0.001), the higher the depressive symptoms levels, the higher the prevalence of T2D. Longitudinal analyses showed that the higher baseline depressive symptoms levels, the higher the likelihood of being within the HbA1c ≥ 7% at 1-year level (Wald-χ2 = 24.06, df = 3, p < .001, for the full adjusted model). Additionally, depressive levels at baseline and duration of T2D predicted higher HbA1c and body mass index, and lower physical activity and adherence to Mediterranean Diet at 1 year of follow-up.This study supports an association between T2D and the severity of depressive symptoms, suggesting a worse metabolic control from mild severity levels in the short-medium term, influenced by lifestyle habits related to diabetes care. Screening for depressive symptoms and a multidisciplinary integrative therapeutic approach should be ensured in patients with T2D.© 2024. The Author(s).
  • Others:

    Author, as appears in the article.: Baenas, I; Camacho-Barcia, L; Granero, R; Razquin, C; Corella, D; Gomez-Martinez, C; Castaner-Nino, O; Martinez, JA; Alonso-Gomez, AM; Waernberg, J; Vioque, J; Romaguera, D; Lopez-Miranda, J; Estruch, R; Tinahones, FJ; Lapetra, J; Serra-Majem, JL; Cano-Ibanez, N; Tur, JA; Martin-Sanchez, V; Pinto, X; Gaforio, JJ; Matia-Martin, P; Vidal, J; Vazquez, C; Daimiel, L; Ros, E; Jimenez-Murcia, S; Dalsgaard, S; Garcia-Arellano, A; Babio, N; Sorli, JV; Lassale, C; Garcia-de-la-Hera, M; Gomez-Garcia, E; Zulet, MA; Konieczna, J; Martin-Pelaez, S; Tojal-Sierra, L; Basterra-Gortari, FJ; de las Heras-delgado, S; Portoles, O; Munoz-Perez, MA; Arenas-Larriva, AP; Compan-Gabucio, L; Eguaras, S; Shyam, S; Fito, M; Banos, RM; Salas-Salvado, J; Fernandez-Aranda, F
    Department: Bioquímica i Biotecnologia
    URV's Author/s: Babio Sánchez, Nancy Elvira / Gómez Martínez, Carlos / Salas Salvadó, Jorge
    Keywords: Type 2 diabetes Severity Physical-activity Metabolic syndrome Hba1c Depressive symptoms severity prevention people mood metabolic syndrome mechanisms hba1c distress diet depressive symptoms adherence
    Abstract: To examine the cross-sectional association between baseline depressive symptoms and the presence of type 2 diabetes (T2D), and its association with glycated hemoglobin (HbA1c) and other metabolic variables, and the prospective association of depressive symptoms and HbA1c after 1 year of follow-up.n = 6224 Mediterranean older adults with overweight/obesity and metabolic syndrome (48% females, mean age 64.9 ± 4.9 years) were evaluated in the framework of the PREDIMED-Plus study cohort. Depressive symptoms were assessed using the Beck Depression Inventory-II and HbA1c was used to measure metabolic control.The presence of T2D increased the likelihood of higher levels of depressive symptoms (χ2 = 15.84, p = 0.001). Polynomial contrast revealed a positive linear relationship (χ2 = 13.49, p = 0.001), the higher the depressive symptoms levels, the higher the prevalence of T2D. Longitudinal analyses showed that the higher baseline depressive symptoms levels, the higher the likelihood of being within the HbA1c ≥ 7% at 1-year level (Wald-χ2 = 24.06, df = 3, p < .001, for the full adjusted model). Additionally, depressive levels at baseline and duration of T2D predicted higher HbA1c and body mass index, and lower physical activity and adherence to Mediterranean Diet at 1 year of follow-up.This study supports an association between T2D and the severity of depressive symptoms, suggesting a worse metabolic control from mild severity levels in the short-medium term, influenced by lifestyle habits related to diabetes care. Screening for depressive symptoms and a multidisciplinary integrative therapeutic approach should be ensured in patients with T2D.© 2024. The Author(s).
    Thematic Areas: Saúde coletiva Odontología Nutrição Medicina iii Medicina ii Medicina i Interdisciplinar General medicine Engenharias iii Enfermagem Endocrinology, diabetes and metabolism Endocrinology & metabolism Endocrinology Educação física Ciências biológicas ii Ciências biológicas i Ciência de alimentos Biotecnología
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: carlos.gomez@urv.cat carlos.gomez@urv.cat jordi.salas@urv.cat nancy.babio@urv.cat
    Author identifier: 0000-0003-2700-7459 0000-0003-3527-5277
    Record's date: 2024-08-03
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://link.springer.com/article/10.1007/s40618-023-02278-y
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Journal Of Endocrinological Investigation. 47 (6): 1405-1418
    APA: Baenas, I; Camacho-Barcia, L; Granero, R; Razquin, C; Corella, D; Gomez-Martinez, C; Castaner-Nino, O; Martinez, JA; Alonso-Gomez, AM; Waernberg, J; V (2024). Association between type 2 diabetes and depressive symptoms after a 1-year follow-up in an older adult Mediterranean population. Journal Of Endocrinological Investigation, 47(6), 1405-1418. DOI: 10.1007/s40618-023-02278-y
    Article's DOI: 10.1007/s40618-023-02278-y
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2024
    Publication Type: Journal Publications
  • Keywords:

    Endocrinology,Endocrinology & Metabolism,Endocrinology, Diabetes and Metabolism
    Type 2 diabetes
    Severity
    Physical-activity
    Metabolic syndrome
    Hba1c
    Depressive symptoms
    severity
    prevention
    people
    mood
    metabolic syndrome
    mechanisms
    hba1c
    distress
    diet
    depressive symptoms
    adherence
    Saúde coletiva
    Odontología
    Nutrição
    Medicina iii
    Medicina ii
    Medicina i
    Interdisciplinar
    General medicine
    Engenharias iii
    Enfermagem
    Endocrinology, diabetes and metabolism
    Endocrinology & metabolism
    Endocrinology
    Educação física
    Ciências biológicas ii
    Ciências biológicas i
    Ciência de alimentos
    Biotecnología
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