Articles producció científica> Ciències Mèdiques Bàsiques

Unveiling potential virulence determinants in Vibrio isolates from Anadara tuberculosa through whole genome analyses

  • Identification data

    Identifier: imarina:9351735
  • Authors:

    Restrepo-Benavides, M
    Lozano-Arce, D
    Gonzalez-Garcia, LN
    Báez-Aguirre, F
    Ariza-Aranguren, G
    Faccini, D
    Zambrano, MM
    Jiménez, P
    Fernández-Bravo, A
    Restrepo, S
    Guevara-Suarez, M
  • Others:

    Author, as appears in the article.: Restrepo-Benavides, M; Lozano-Arce, D; Gonzalez-Garcia, LN; Báez-Aguirre, F; Ariza-Aranguren, G; Faccini, D; Zambrano, MM; Jiménez, P; Fernández-Bravo, A; Restrepo, S; Guevara-Suarez, M
    Department: Ciències Mèdiques Bàsiques
    URV's Author/s: Fernández Bravo, Ana
    Keywords: United-states Toxin Secretion systems Piangua Penaeus-monodon fabricius Parahaemolyticus Oxford nanopore Multidrug resistance Infections Iii secretion systems Identification Host Gridion Effector protein Bivalve Alginolyticus
    Abstract: The genus Vibrio includes pathogenic bacteria able to cause disease in humans and aquatic organisms, leading to disease outbreaks and significant economic losses in the fishery industry. Despite much work on Vibrio in several marine organisms, no specific studies have been conducted on Anadara tuberculosa. This is a commercially important bivalve species, known as "piangua hembra," along Colombia's Pacific coast. Therefore, this study aimed to identify and characterize the genomes of Vibrio isolates obtained from A. tuberculosa. Bacterial isolates were obtained from 14 A. tuberculosa specimens collected from two locations along the Colombian Pacific coast, of which 17 strains were identified as Vibrio: V. parahaemolyticus (n = 12), V. alginolyticus (n = 3), V. fluvialis (n = 1), and V. natriegens (n = 1). Whole genome sequence of these isolates was done using Oxford Nanopore Technologies (ONT). The analysis revealed the presence of genes conferring resistance to beta-lactams, tetracyclines, chloramphenicol, and macrolides, indicating potential resistance to these antimicrobial agents. Genes associated with virulence were also found, suggesting the potential pathogenicity of these Vibrio isolates, as well as genes for Type III Secretion Systems (T3SS) and Type VI Secretion Systems (T6SS), which play crucial roles in delivering virulence factors and in interbacterial competition. This study represents the first genomic analysis of bacteria within A. tuberculosa, shedding light on Vibrio genetic factors and contributing to a comprehensive understanding of the pathogenic potential of these Vibrio isolates.
    Thematic Areas: Physiology Microbiology (medical) Microbiology Infectious diseases Immunology and microbiology (miscellaneous) Immunology and microbiology (all) Genetics General medicine General immunology and microbiology Ecology Ciências agrárias i Cell biology
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: ana.fernandez@urv.cat
    Author identifier: 0000-0001-7637-5958
    Record's date: 2024-07-20
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://journals.asm.org/doi/10.1128/spectrum.02928-23
    Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Microbiology Spectrum. 12 (2): e02928-23-
    APA: Restrepo-Benavides, M; Lozano-Arce, D; Gonzalez-Garcia, LN; Báez-Aguirre, F; Ariza-Aranguren, G; Faccini, D; Zambrano, MM; Jiménez, P; Fernández-Bravo (2024). Unveiling potential virulence determinants in Vibrio isolates from Anadara tuberculosa through whole genome analyses. Microbiology Spectrum, 12(2), e02928-23-. DOI: 10.1128/spectrum.02928-23
    Article's DOI: 10.1128/spectrum.02928-23
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2024
    Publication Type: Journal Publications
  • Keywords:

    Cell Biology,Ecology,Genetics,Immunology and Microbiology (Miscellaneous),Infectious Diseases,Microbiology,Microbiology (Medical),Physiology
    United-states
    Toxin
    Secretion systems
    Piangua
    Penaeus-monodon fabricius
    Parahaemolyticus
    Oxford nanopore
    Multidrug resistance
    Infections
    Iii secretion systems
    Identification
    Host
    Gridion
    Effector protein
    Bivalve
    Alginolyticus
    Physiology
    Microbiology (medical)
    Microbiology
    Infectious diseases
    Immunology and microbiology (miscellaneous)
    Immunology and microbiology (all)
    Genetics
    General medicine
    General immunology and microbiology
    Ecology
    Ciências agrárias i
    Cell biology
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