Author, as appears in the article.: Noronha JC; Nishi SK; Khan TA; Blanco Mejia S; Kendall CWC; Kahleová H; Rahelić D; Salas-Salvadó J; Leiter LA; Lean MEJ; Sievenpiper JL
Department: Bioquímica i Biotecnologia
URV's Author/s: Nishi, Stephanie Kimiko / Salas Salvadó, Jorge
Keywords: Meal replacements Metabolic syndrome Prediabetes Weight management
Abstract: This review synthesized the evidence from randomized controlled trials comparing the effect of meal replacements (MRs) as part of a weight loss intervention with conventional food-based weight loss diets on cardiometabolic risk in individuals with pre-diabetes and features of metabolic syndrome. MEDLINE, EMBASE, and Cochrane Library were searched through January 16, 2024. Data were pooled using the generic inverse variance method and expressed as mean difference [95% confidence intervals]. The overall certainty of the evidence was assessed using GRADE. Ten trials (n = 1254) met the eligibility criteria. MRs led to greater reductions in body weight (-1.38 kg [-1.81, -0.95]), body mass index (BMI, -0.56 kg/m2 [-0.78, -0.34]), waist circumference (-1.17 cm [-1.93, -0.41]), HbA1c (-0.11% [-0.22, 0.00]), LDL-c (-0.18 mmol/L [-0.28, -0.08]), non-HDL-c (-0.17 mmol/L [-0.33, -0.01]), and systolic blood pressure (-2.22 mmHg [-4.20, -0.23]). The overall certainty of the evidence was low to moderate owing to imprecision and/or inconsistency. The available evidence suggests that incorporating MRs into a weight loss intervention leads to small important reductions in body weight, BMI, LDL-c, non-HDL-c, and systolic blood pressure, and trivial reductions in waist circumference and HbA1c, beyond that seen with conventional food-based weight loss diets.© 2024 The Authors. Obesity Reviews published by John Wiley & Sons Ltd on behalf of World Obesity Federation.
Thematic Areas: Ciências ambientais Ciências biológicas ii Ciências biológicas iii Educação física Endocrinology & metabolism Endocrinology, diabetes and metabolism Enfermagem General medicine Medicina i Medicina ii Medicina iii Nutrição Odontología Public health, environmental and occupational health Saúde coletiva
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: jordi.salas@urv.cat stephanie.nishi@urv.cat
Author identifier: 0000-0003-2700-7459
Record's date: 2024-06-22
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://onlinelibrary.wiley.com/doi/10.1111/obr.13751
Papper original source: Obesity Reviews. 25 (7): e13751-e13751
APA: Noronha JC; Nishi SK; Khan TA; Blanco Mejia S; Kendall CWC; Kahleová H; Rahelić D; Salas-Salvadó J; Leiter LA; Lean MEJ; Sievenpiper JL (2024). Weight management using meal replacements and cardiometabolic risk reduction in individuals with pre-diabetes and features of metabolic syndrome: A systematic review and meta-analysis of randomized controlled trials. Obesity Reviews, 25(7), e13751-e13751. DOI: 10.1111/obr.13751
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Article's DOI: 10.1111/obr.13751
Entity: Universitat Rovira i Virgili
Journal publication year: 2024
Publication Type: Journal Publications