Articles producció científica> Bioquímica i Biotecnologia

Weight management using meal replacements and cardiometabolic risk reduction in individuals with pre-diabetes and features of metabolic syndrome: A systematic review and meta-analysis of randomized controlled trials

  • Identification data

    Identifier: imarina:9366331
    Authors:
    Noronha JCNishi SKKhan TABlanco Mejia SKendall CWCKahleová HRahelić DSalas-Salvadó JLeiter LALean MEJSievenpiper JL
    Abstract:
    This review synthesized the evidence from randomized controlled trials comparing the effect of meal replacements (MRs) as part of a weight loss intervention with conventional food-based weight loss diets on cardiometabolic risk in individuals with pre-diabetes and features of metabolic syndrome. MEDLINE, EMBASE, and Cochrane Library were searched through January 16, 2024. Data were pooled using the generic inverse variance method and expressed as mean difference [95% confidence intervals]. The overall certainty of the evidence was assessed using GRADE. Ten trials (n = 1254) met the eligibility criteria. MRs led to greater reductions in body weight (-1.38 kg [-1.81, -0.95]), body mass index (BMI, -0.56 kg/m2 [-0.78, -0.34]), waist circumference (-1.17 cm [-1.93, -0.41]), HbA1c (-0.11% [-0.22, 0.00]), LDL-c (-0.18 mmol/L [-0.28, -0.08]), non-HDL-c (-0.17 mmol/L [-0.33, -0.01]), and systolic blood pressure (-2.22 mmHg [-4.20, -0.23]). The overall certainty of the evidence was low to moderate owing to imprecision and/or inconsistency. The available evidence suggests that incorporating MRs into a weight loss intervention leads to small important reductions in body weight, BMI, LDL-c, non-HDL-c, and systolic blood pressure, and trivial reductions in waist circumference and HbA1c, beyond that seen with conventional food-based weight loss diets.© 2024 The Authors. Obesity Reviews published by John Wiley & Sons Ltd on behalf of World Obesity Federation.
  • Others:

    Author, as appears in the article.: Noronha JC; Nishi SK; Khan TA; Blanco Mejia S; Kendall CWC; Kahleová H; Rahelić D; Salas-Salvadó J; Leiter LA; Lean MEJ; Sievenpiper JL
    Department: Bioquímica i Biotecnologia
    URV's Author/s: Nishi, Stephanie Kimiko / Salas Salvadó, Jorge
    Keywords: Meal replacements Metabolic syndrome Prediabetes Weight management
    Abstract: This review synthesized the evidence from randomized controlled trials comparing the effect of meal replacements (MRs) as part of a weight loss intervention with conventional food-based weight loss diets on cardiometabolic risk in individuals with pre-diabetes and features of metabolic syndrome. MEDLINE, EMBASE, and Cochrane Library were searched through January 16, 2024. Data were pooled using the generic inverse variance method and expressed as mean difference [95% confidence intervals]. The overall certainty of the evidence was assessed using GRADE. Ten trials (n = 1254) met the eligibility criteria. MRs led to greater reductions in body weight (-1.38 kg [-1.81, -0.95]), body mass index (BMI, -0.56 kg/m2 [-0.78, -0.34]), waist circumference (-1.17 cm [-1.93, -0.41]), HbA1c (-0.11% [-0.22, 0.00]), LDL-c (-0.18 mmol/L [-0.28, -0.08]), non-HDL-c (-0.17 mmol/L [-0.33, -0.01]), and systolic blood pressure (-2.22 mmHg [-4.20, -0.23]). The overall certainty of the evidence was low to moderate owing to imprecision and/or inconsistency. The available evidence suggests that incorporating MRs into a weight loss intervention leads to small important reductions in body weight, BMI, LDL-c, non-HDL-c, and systolic blood pressure, and trivial reductions in waist circumference and HbA1c, beyond that seen with conventional food-based weight loss diets.© 2024 The Authors. Obesity Reviews published by John Wiley & Sons Ltd on behalf of World Obesity Federation.
    Thematic Areas: Ciências ambientais Ciências biológicas ii Ciências biológicas iii Educação física Endocrinology & metabolism Endocrinology, diabetes and metabolism Enfermagem General medicine Medicina i Medicina ii Medicina iii Nutrição Odontología Public health, environmental and occupational health Saúde coletiva
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: jordi.salas@urv.cat stephanie.nishi@urv.cat
    Author identifier: 0000-0003-2700-7459
    Record's date: 2024-06-22
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://onlinelibrary.wiley.com/doi/10.1111/obr.13751
    Papper original source: Obesity Reviews. 25 (7): e13751-e13751
    APA: Noronha JC; Nishi SK; Khan TA; Blanco Mejia S; Kendall CWC; Kahleová H; Rahelić D; Salas-Salvadó J; Leiter LA; Lean MEJ; Sievenpiper JL (2024). Weight management using meal replacements and cardiometabolic risk reduction in individuals with pre-diabetes and features of metabolic syndrome: A systematic review and meta-analysis of randomized controlled trials. Obesity Reviews, 25(7), e13751-e13751. DOI: 10.1111/obr.13751
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Article's DOI: 10.1111/obr.13751
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2024
    Publication Type: Journal Publications
  • Keywords:

    Endocrinology & Metabolism,Endocrinology, Diabetes and Metabolism,Public Health, Environmental and Occupational Health
    Meal replacements
    Metabolic syndrome
    Prediabetes
    Weight management
    Ciências ambientais
    Ciências biológicas ii
    Ciências biológicas iii
    Educação física
    Endocrinology & metabolism
    Endocrinology, diabetes and metabolism
    Enfermagem
    General medicine
    Medicina i
    Medicina ii
    Medicina iii
    Nutrição
    Odontología
    Public health, environmental and occupational health
    Saúde coletiva
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