Author, as appears in the article.: Ruiz-Limon, Patricia; Muralidharan, Jananee; Gomez-Perez, Ana M; Murri, Mora; Vioque, Jesus; Corella, Dolores; Fito, Montse; Vidal, Josep; Salas-Salvado, Jordi; Torres-Collado, Laura; Coltell, Oscar; Bullo, Monica; Bernal-Lopez, M Rosa; Moreno-Indias, Isabel
Department: Bioquímica i Biotecnologia
URV's Author/s: Atzeni, Alessandro / Bulló Bonet, Mònica / Martínez Rodríguez, María Ángeles / Muralidharan, Jananee / Salas Salvadó, Jorge
Keywords: Physical activity Overweight Overweigh Obesity Metabolic syndrome Gut microbiota
Abstract: We aimed to identify how physical activity (PA), within the context of a Mediterranean diet, affects metabolic variables and gut microbiota in older individuals with overweight/obesity and metabolic syndrome. Observational analysis was conducted as part of the PREDIMED-Plus study with 152 males and 145 females with overweight/obesity and metabolic syndrome. General assessments, anthropometric and biochemical measurements, and gut microbial 16S rRNA sequencing data were analyzed at baseline and 1-year of follow-up. Participants were stratified by tertiles of 1-year change in total PA-related energy expenditure ranging from -98.77 to 1099.99 METs (min/week). The total PA percentage of change was reduced in tertile 1 (-44.83 +/- 24.94), increased in tertile 2 (28.96 +/- 23.33) and tertile 3 (273.64 +/- 221.42). Beta diversity analysis showed differences in the gut microbiota population within each tertile group. Significant differences were found at phylum, family, and genus levels in the gut microbiota of the three tertile groups at baseline and 1-year timepoint. Tertile 3, the group with the greatest increase in PA, was characterized by increases in their levels of Sutterella, Bilophila, and Lachnospira bacteria as well as a reduction in Collinsella. Moreover, this tertile showed a different pattern in its predicted metabolic capacities to the other groups. Our results have microbiota profile. This modulation of gut microbiome populations and their metabolic capacities may contribute to the health of the aged individuals with overweight/obesity and metabolic syndrome.
Thematic Areas: Sports science Sport sciences Psicología Physiology (medical) Physical therapy, sports therapy and rehabilitation Orthopedics and sports medicine Odontología Nutrição Medicina ii Medicina i Interdisciplinar Engenharias iv Educação física Ciências biológicas ii Ciências biológicas i Biotecnología
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: alessandro.atzeni@urv.cat mangeles.martinez@urv.cat alessandro.atzeni@urv.cat monica.bullo@urv.cat jordi.salas@urv.cat
Author identifier: 0000-0002-1804-8606 0000-0001-8595-3772 0000-0002-1804-8606 0000-0002-0218-7046 0000-0003-2700-7459
Record's date: 2024-10-12
Paper version: info:eu-repo/semantics/publishedVersion
Paper original source: Biology Of Sport. 41 (3): 47-60
APA: Ruiz-Limon, Patricia; Muralidharan, Jananee; Gomez-Perez, Ana M; Murri, Mora; Vioque, Jesus; Corella, Dolores; Fito, Montse; Vidal, Josep; Salas-Salva (2024). Physical activity shifts gut microbiota structure in aged subjects with overweight/obesity and metabolic syndrome. Biology Of Sport, 41(3), 47-60. DOI: 10.5114/biolsport.2024.133005
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Entity: Universitat Rovira i Virgili
Journal publication year: 2024
Publication Type: Journal Publications
Repositori URV