α-Boryl Carbanions: The Influence of Geminal Heteroatoms in C-C Bond Formation

Identifier:  imarina:9440133

Handle: https://hdl.handle.net/20.500.11797/imarina9440133

Authors:  Fernandez, Elena

Abstract:
The wide applications of alpha-boryl carbanions in selective coupling with organohalides, imines/carbonyls and conjugated unsaturated substrates has become an interesting tool for organic synthesis. Strategically, the inclusion of heteroatoms, such as Si, S, N, F, Cl, Br and I in the alpha position opens a new venue towards multifunctionalities in molecular design. Here, a conceptual and practical view on powerful carbanions, containing alpha-silicoboron, alpha-thioboron, alpha-haloboron and alpha-aminoboron is given, as well as a prespective on their efficient application for selective electrophilic trapping.