Autor según el artículo: Montserrat Diéguez Oscar Pàmies MARIA BIOSCA Carlota Borràs
Departamento: Química Física i Inorgànica
Autor/es de la URV: DIÉGUEZ FERNÁNDEZ, MONTSERRAT PAMIES OLLÉ, OSCAR MARIA BIOSCA BORRÀS NOGUERA, CARLOTA
Palabras clave: reaction intermediates asymmetric catalysis iridium
Resumen: We report a reduced but structurally valuable
phosphite/phosphinite-thioether ligand library for the Irhydrogenation
of 40 minimally functionalized alkenes,
including relevant examples with poorly coordinative groups.
We found that enantiomeric excesses are mainly dependent on
the substrate structure and on some ligand parameters (i.e., the
type of thioether/phosphorus moieties and the configuration of
the phosphite group), whereas the substituents of the biaryl
phosphite moiety had little impact. By tuning the ligand
parameters we were able to find highly selective catalysts for a
range of substrates (ee’s up to 99%). These phosphite/phosphinite-thioether ligands have a simple backbone and thus yield
simple NMR spectra that reduce signal overlap and facilitate the identification of relevant intermediates. Therefore, by combining
HP-NMR spectroscopy and theoretical studies, we were also able to identify the catalytically competent Ir-dihydride alkene
species, which made it possible to explain the enantioselectivity obtained.
Grupo de investigación: Organometàl.lics i Catàlisi Homogènia
Áreas temáticas: Chemistry Química Química
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 0276-7333
Identificador del autor: 0000-0002-8450-0656 0000-0002-2352-8508 n/a n/a
Fecha de alta del registro: 2015-11-18
Página final: 5334
Volumen de revista: 34
Versión del articulo depositado: info:eu-repo/semantics/acceptedVersion
Enlace a la fuente original: https://pubs.acs.org/doi/10.1021/acs.organomet.5b00790
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
DOI del artículo: 10.1021/acs.organomet.5b00790
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2015
Página inicial: 5321
Tipo de publicación: Post-print
Repositori URV