Autor según el artículo: Montserrat Diéguez Sabina Alegre Yvette Mata Oscar Pàmies

Departamento: Química Física i Inorgànica

Autor/es de la URV: DIÉGUEZ FERNÁNDEZ, MONTSERRAT Sabina Alegre Yvette Mata PAMIES OLLÉ, OSCAR

Palabras clave: asymmetric catalysis palladium allylic substitution

Resumen: We have applied a modular sugar-based phosphite ligand library for the Pd-catalyzed allylic substitution reactions of several substrates. These ligands are derived from D-(+)-glucose, D-(+)-galactose and D-(+)- fructose, which lead to a wide range of sugar backbones, and contain several substituents at the C-3 carbon of the furanoside backbone and several substituents/ configurations in the biaryl moiety, with different steric and electronic properties. Systematic variation of the ligand parameters indicates that the catalytic performance (activities and enantioselectivities) is highly affected by sugar backbone, the substituents at the C-3 carbon of the furanoside backbone, the configurations at the C-3 and C-4 carbons of the ligand backbone and the type of substituents/configurations in the biaryl phosphite moiety as well as the substrate type. For disubstituted substrates moderate enantioselectivities (up to 72%) were achieved using ligand L8d, while for monosubstituted substrates the highest enantioselectivities (up to 40%) were obtained using ligand L9a

Grupo de investigación: Organometàl.lics i Catàlisi Homogènia

Áreas temáticas: Química Química Chemistry

Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 2300-4630

Identificador del autor: 0000-0002-8450-0656 n/a n/a 0000-0002-2352-8508

Fecha de alta del registro: 2015-11-18

Página final: 39

Versión del articulo depositado: info:eu-repo/semantics/publishedVersion

Enlace a la fuente original: http://www.degruyter.com/view/j/asorg.2014.1.issue-1/asorg-2014-0001/asorg-2014-0001.xml

DOI del artículo: 10.2478/asorg-2014-0001

Entidad: Universitat Rovira i Virgili

Año de publicación de la revista: 2014

Página inicial: 32

Tipo de publicación: Article