Autor según el artículo: Montserrat Diéguez Sabina Alegre Yvette Mata Oscar Pàmies
Departamento: Química Física i Inorgànica
Autor/es de la URV: DIÉGUEZ FERNÁNDEZ, MONTSERRAT Sabina Alegre Yvette Mata PAMIES OLLÉ, OSCAR
Palabras clave: asymmetric catalysis palladium allylic substitution
Resumen: We have applied a modular sugar-based
phosphite ligand library for the Pd-catalyzed allylic
substitution reactions of several substrates. These ligands
are derived from D-(+)-glucose, D-(+)-galactose and D-(+)-
fructose, which lead to a wide range of sugar backbones,
and contain several substituents at the C-3 carbon of
the furanoside backbone and several substituents/
configurations in the biaryl moiety, with different steric
and electronic properties. Systematic variation of the
ligand parameters indicates that the catalytic performance
(activities and enantioselectivities) is highly affected by
sugar backbone, the substituents at the C-3 carbon of
the furanoside backbone, the configurations at the C-3
and C-4 carbons of the ligand backbone and the type
of substituents/configurations in the biaryl phosphite
moiety as well as the substrate type. For disubstituted
substrates moderate enantioselectivities (up to 72%) were
achieved using ligand L8d, while for monosubstituted
substrates the highest enantioselectivities (up to 40%)
were obtained using ligand L9a
Grupo de investigación: Organometàl.lics i Catàlisi Homogènia
Áreas temáticas: Química Química Chemistry
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 2300-4630
Identificador del autor: 0000-0002-8450-0656 n/a n/a 0000-0002-2352-8508
Fecha de alta del registro: 2015-11-18
Página final: 39
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: http://www.degruyter.com/view/j/asorg.2014.1.issue-1/asorg-2014-0001/asorg-2014-0001.xml
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
DOI del artículo: 10.2478/asorg-2014-0001
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2014
Página inicial: 32
Tipo de publicación: Article