Autor según el artículo: Montserrat Giralt; Gabriel Dasilva; Manuel Pazos; Eduardo García-Egido; Jara Pérez-Jiménez; Josep Lluis Torres; María-Rosa Nogués; Isabel Medina
Departamento: Ciències Mèdiques Bàsiques
Autor/es de la URV: GIRALT BATISTA, MONTSERRAT; Gabriel Dasilva; Manuel Pazos; Eduardo García-Egido; Jara Pérez-Jiménez; Josep Lluis Torres; NOGUÉS LLORT, MARIA ROSA; Isabel Medina
Palabras clave: Metabolism FATTY ACIDS Biomarkers
Resumen: The role of specific proportions of ω-3 EPA and DHA, in the modulation of inflammation and oxidative stress markers associated to the progression of Metabolic Syndrome was investigated. Potential inflammatory eicosanoids and docosanoids were discussed together to biomarkers of CVD, obesity, inflammation and oxidative stress in an animal model of metabolic disorders. Results evidenced a noteworthy health effect of 1:1 and 2:1 EPA:DHA proportions over 1:2 EPA:DHA based diets through a down-regulation in the production of strong pro-inflammatory ω-6 eicosanoids, a decrement of biomarkers of oxidative stress, and a modulation of fatty acid desaturase activities and plasma and membrane PUFAs towards greater anti-inflammatory profiles. Outcomes contribute to the general knowledge on the health benefits of marine lipids and their role on the progress of MetS, inflammation and oxidative stress. Results shed light on controversial protective mechanisms of EPA and DHA to better design dietary interventions aimed at reducing MetS.
Grupo de investigación: Farmacobiologia Cel.lular
Áreas temáticas: Health sciences Ciencias de la salud Ciències de la salut
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 0308-8146
Identificador del autor: S/D; S/D; S/D; S/D; S/D; S/D; S/D; S/D
Fecha de alta del registro: 2016-04-27
Página final: 203
Volumen de revista: 205
Versión del articulo depositado: info:eu-repo/semantics/submittedVersion
Enlace a la fuente original: https://www.sciencedirect.com/science/article/abs/pii/S0308814616303715?via%3Dihub
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
DOI del artículo: 10.1016/j.foodchem.2016.03.020
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2016
Página inicial: 196
Tipo de publicación: Article Artículo Article
Repositori URV