Articles producció científica> Bioquímica i Biotecnologia

The respiratory quotient as a prognostic factor in weight-loss rebound.

  • Datos identificativos

    Identificador: PC:1615
    Autores:
    J Salas SalvadoS ValtueñaPG Lorda
    Resumen:
    OBJECTIVE: To investigate the possible metabolic factors predisposing to weight gain subsequent to the cessation of a rapid-weight-loss diet. DESIGN: Prospective, longitudinal, intervention study of a 2MJ diet daily for 28 d in a metabolic ward followed by a 12- month outpatient follow-up under a conventional, hypocaloric diet. SUBJECTS: Thirty-five females and one male, all with morbid obesity defined by a body mass index_35 kg/m2. MEASUREMENTS: VO2 and VCO2 measured by 30 min indirect calorimetry to calculate resting energy expenditure and resting respiratory quotient at the beginning and end of very-low-calorie diet; body composition assessed by hydrostatic weighing on day 1; weight recorded on days 1 and 28 and at follow-up of 3, 6 and 12 months. RESULTS: From among all the variables considered, the resting respiratory quotient measured on day 28, even adjusted for weight loss during hospitalisation, was the only one that correlated significantly with the weight changes recorded during follow-up. CONCLUSION: Subjects who showed a respiratory quotient on day 28 in the lower range (<0.72) were more able to maintain the weight-loss achieved with the very-low-calorie diet while those in the higher range (>0.75) were less able to do so over the follow-up period. Thus, an appropriately measured respiratory quotient could prove useful in clinical practice as a prognostic marker of the long-term effectiveness of low- and very-low-calorie diets used to induce rapid weight loss.
  • Otros:

    Autor según el artículo: J Salas Salvado; S Valtueña ; PG Lorda
    Departamento: Bioquímica i Biotecnologia
    Autor/es de la URV: SALAS SALVADÓ, JORGE; S Valtueña ; PG Lorda
    Palabras clave: resting energy expenditure respiratory quotient obesity
    Resumen: OBJECTIVE: To investigate the possible metabolic factors predisposing to weight gain subsequent to the cessation of a rapid-weight-loss diet. DESIGN: Prospective, longitudinal, intervention study of a 2MJ diet daily for 28 d in a metabolic ward followed by a 12- month outpatient follow-up under a conventional, hypocaloric diet. SUBJECTS: Thirty-five females and one male, all with morbid obesity defined by a body mass index_35 kg/m2. MEASUREMENTS: VO2 and VCO2 measured by 30 min indirect calorimetry to calculate resting energy expenditure and resting respiratory quotient at the beginning and end of very-low-calorie diet; body composition assessed by hydrostatic weighing on day 1; weight recorded on days 1 and 28 and at follow-up of 3, 6 and 12 months. RESULTS: From among all the variables considered, the resting respiratory quotient measured on day 28, even adjusted for weight loss during hospitalisation, was the only one that correlated significantly with the weight changes recorded during follow-up. CONCLUSION: Subjects who showed a respiratory quotient on day 28 in the lower range (<0.72) were more able to maintain the weight-loss achieved with the very-low-calorie diet while those in the higher range (>0.75) were less able to do so over the follow-up period. Thus, an appropriately measured respiratory quotient could prove useful in clinical practice as a prognostic marker of the long-term effectiveness of low- and very-low-calorie diets used to induce rapid weight loss.
    Grupo de investigación: Alimentació, Nutrició, Creixement i Salut Mental
    Áreas temáticas: Bioquímica i biotecnologia Bioquímica y tecnología Biochemistry and technology
    Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 0307-0565
    Identificador del autor: orcid.org/0000-0003-2700-7459; N/D; N/D
    Fecha de alta del registro: 2016-06-08
    Página final: 817
    Volumen de revista: 21
    Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
    Enlace a la fuente original: https://www.nature.com/articles/0800480?utm_medium=affiliate&utm_source=commission_junction&utm_campaign=3_nsn6445_deeplink_PID2190813&utm_content=deeplink
    URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
    DOI del artículo: 10.1038/sj.ijo.0800480
    Entidad: Universitat Rovira i Virgili
    Año de publicación de la revista: 1997
    Página inicial: 811
    Tipo de publicación: Article Artículo Article
  • Palabras clave:

    Obesitat
    Despesa Energètica Basal
    resting energy expenditure
    respiratory quotient
    obesity
    Bioquímica i biotecnologia
    Bioquímica y tecnología
    Biochemistry and technology
    0307-0565
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