Articles producció científica> Bioquímica i Biotecnologia

Participation in a pharmacological trial does not alter participants' dietary habits.

  • Datos identificativos

    Identificador: PC:1625
    Autores:
    Jordi SalasVictoria ArijaCarme PiñolSonia Valles
    Resumen:
    OBJECTIVE: The aim of this study was to observe whether the act of participation in a well-controlled clinical trial can, co-incidentally, modify the dyslipaemic patient's adherence to his/her diet. DESIGN AND SUBJECT: Food diaries of 55 men and 51 women (aged 46.4 +/- 10.6 and 55.8 +/- 12.1 years respectively) were analyzed at the beginning and the end of the double-blind stage of treatment (12 weeks). STATISTICS: Variance analysis and multi-variant analysis with repeated data by SPSS/PC statistical package. RESULTS: In neither sex were there any statistically significant differences between the start and end of the study with respect to the intake of energy, proteins, total lipids, carbohydrates, saturated fatty acids, polyunsaturated fatty acids, cholesterol, fibre and alcohol. CONCLUSIONS: Although in individual cases some changes in dietary awareness can occur, on a larger scale, the hypocholesterolaemic intervention trial induced no significant overall changes in the participants dietary/lifestyle patterns and, as such, augurs well for other such trials in which the effect of the therapy may sometimes be confounded by changes in the patients' life-style patterns coincidental to the act of participation in the trial.
  • Otros:

    Autor según el artículo: Jordi Salas; Victoria Arija; Carme Piñol; Sonia Valles
    Departamento: Bioquímica i Biotecnologia
    Autor/es de la URV: SALAS SALVADÓ, JORGE; Victoria Arija; Carme Piñol; Sonia Valles
    Palabras clave: pharmacological trial dietary habits
    Resumen: OBJECTIVE: The aim of this study was to observe whether the act of participation in a well-controlled clinical trial can, co-incidentally, modify the dyslipaemic patient's adherence to his/her diet. DESIGN AND SUBJECT: Food diaries of 55 men and 51 women (aged 46.4 +/- 10.6 and 55.8 +/- 12.1 years respectively) were analyzed at the beginning and the end of the double-blind stage of treatment (12 weeks). STATISTICS: Variance analysis and multi-variant analysis with repeated data by SPSS/PC statistical package. RESULTS: In neither sex were there any statistically significant differences between the start and end of the study with respect to the intake of energy, proteins, total lipids, carbohydrates, saturated fatty acids, polyunsaturated fatty acids, cholesterol, fibre and alcohol. CONCLUSIONS: Although in individual cases some changes in dietary awareness can occur, on a larger scale, the hypocholesterolaemic intervention trial induced no significant overall changes in the participants dietary/lifestyle patterns and, as such, augurs well for other such trials in which the effect of the therapy may sometimes be confounded by changes in the patients' life-style patterns coincidental to the act of participation in the trial.
    Grupo de investigación: Alimentació, Nutrició, Creixement i Salut Mental
    Áreas temáticas: Bioquímica i biotecnologia Bioquímica y tecnología Biochemistry and technology
    Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 0300-9831
    Identificador del autor: orcid.org/0000-0003-2700-7459; orcid.org/0000-0002-1758-0975; N/D; N/D
    Fecha de alta del registro: 2016-06-08
    Página final: 124
    Volumen de revista: 68
    Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
    URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
    Entidad: Universitat Rovira i Virgili
    Año de publicación de la revista: 1998
    Página inicial: 120
    Tipo de publicación: Article Artículo Article
  • Palabras clave:

    Hàbits alimentaris
    Assaig clínic
    pharmacological trial
    dietary habits
    Bioquímica i biotecnologia
    Bioquímica y tecnología
    Biochemistry and technology
    0300-9831
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