Autor según el artículo: Jordi Salas-Salvado; Joan Fernandez-Ballart; Emilio Ros; Miguel Angel Martinez Gonzalez; Montserrat Fito; Ramon Estruch; Dolores Corella; Miquel Fiol; Enrique Gomez Gracia; Fernando Aros; Gemma Flores; Jose Lapetra; Rosa Lamuela Raventos; Valentina Ruiz Gutierrez; Mònica Bullo; Josep Basora; Maria Isabel Covas; the PREDIMED Study Investigators
Departamento: Bioquímica i Biotecnologia
Autor/es de la URV: SALAS SALVADÓ, JORGE; Joan Fernandez-Ballart; Emilio Ros; Miguel Angel Martinez Gonzalez; Montserrat Fito; Ramon Estruch; Dolores Corella; Miquel Fiol; Enrique Gomez Gracia; Fernando Aros; Gemma Flores; Jose Lapetra; Rosa Lamuela Raventos; Valentina Ruiz Gutierrez; BULLÓ BONET, MÒNICA; Josep Basora; Maria Isabel Covas; the PREDIMED Study Investigators
Palabras clave: Metabolic Syndrome Status PREDIMED study Randomized trial
Resumen: BACKGROUND:
Epidemiological studies suggest that the Mediterranean diet (MedDiet) may reduce the risk of developing the metabolic syndrome (MetS). We compared the 1-year effect of 2 behavioral interventions to implement the MedDiet vs advice on a low-fat diet on MetS status.
METHODS:
A total of 1224 participants were recruited from the PREDIMED (Prevención con Dieta Mediterránea) Study, a multicenter, 3-arm, randomized clinical trial to determine the efficacy of the MedDiet on the primary prevention of cardiovascular disease. Participants were older subjects at high risk for cardiovascular disease. Interventions were quarterly education about the MedDiet plus provision of either 1 L/wk of virgin olive oil (MedDiet + VOO) or 30 g/d of mixed nuts (MedDiet + nuts), and advice on a low-fat diet (control diet). All diets were ad libitum, and there was no increase in physical activity for any of the interventions. Lifestyle variables and MetS features as defined by the National Cholesterol Education Program Adult Treatment Panel III criteria were assessed.
RESULTS:
At baseline, 61.4% of participants met criteria for the MetS. One-year prevalence was reduced by 6.7%, 13.7%, and 2.0% in the MedDiet + VOO, MedDiet + nuts, and control diet groups, respectively (MedDiet + nuts vs control groups, P = .01; MedDiet + VOO vs control group, P = .18). Incident rates of the MetS were not significantly different among groups (22.9%, 17.9%, and 23.4%, respectively). After adjustment for sex, age, baseline obesity status, and weight changes, the odds ratios for reversion of MetS were 1.3 (95% confidence interval, 0.8-2.1) for the MedDiet + VOO group and 1.7 (1.1-2.6) for the MedDiet + nuts group compared with the control diet group.
CONCLUSION:
A traditional MedDiet enriched with nuts could be a useful tool in the management of the MetS.
Grupo de investigación: Alimentació, Nutrició, Creixement i Salut Mental
Áreas temáticas: Biochemistry and technology Bioquímica y tecnología Bioquímica i biotecnologia
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 0003-9926
Identificador del autor: N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D
Fecha de alta del registro: 2016-06-13
Página final: 2458
Volumen de revista: 168
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/773456
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2008
Página inicial: 2449
Tipo de publicación: Article Artículo Article
Repositori URV