Autor según el artículo: Oscar Pàmies; Jèssica Margalef; Montserrat Diéguez
Departamento: Química Física i Inorgànica
Autor/es de la URV: PAMIES OLLÉ, OSCAR; Jèssica Margalef; DIÉGUEZ FERNÁNDEZ, MONTSERRAT
Palabras clave: asymmetric transfer hydrogenation ketones sugar-based ligands
Resumen: Asymmetric transfer hydrogenation (ATH) has emerged as one of the most effective and sustainable synthetic
tool for synthesizing enantiopure alcohols. Since Noyori’s group successfully applied Ru-catalysts
modified with chiral b-amino alcohols or diamines as ligands, a large number of catalytic systems has
been successfully developed. However, further improvement in terms of substrate scope, selectivity,
and turnover frequency are required to make the process competitive with conventional hydrogenations.
Overcoming these limitations requires research toward the design of new ligands. Such a task becomes
easier if readily modulable chiral ligands are at hand. Sugar-based ligands are particularly useful for
addressing this need. They are readily available, highly functionalized, and their modular constructions
are easy. Series of chiral ligands can be screened in the search for high activities and selectivities for each
type of substrate. This digest paper will discuss the progress on the use of sugar-based ligands in ATH
reactions.
Grupo de investigación: Organometàl.lics i Catàlisi Homogènia
Áreas temáticas: Química Química Chemistry
Acceso a la licencia de uso: thttps://creativecommons.org/licenses/by/3.0/es/
ISSN: 0040-4039
Identificador del autor: 0000-0002-2352-8508; n/a; 0000-0002-8450-0656
Fecha de alta del registro: 2017-02-22
Página final: 1308
Volumen de revista: 57
Versión del articulo depositado: info:eu-repo/semantics/acceptedVersion
Enlace a la fuente original: https://www.sciencedirect.com/science/article/pii/S0040403916301320
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
DOI del artículo: https://doi.org/10.1016/j.tetlet.2016.02.022
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2016
Página inicial: 1301
Tipo de publicación: Post-print
Repositori URV