Articles producció científica> Medicina i Cirurgia

Extended dual antiplatelet therapy after acute coronary syndrome in Spain: Results from the EPICOR study

  • Datos identificativos

    Identificador: PC:2624
    Autores:
    Bardají, A.Leal, M.Arrarte, V.Garcia-Moll, X.Pérez de Isla, L.Bueno, H.
    Resumen:
    Filiació URV: SI
  • Otros:

    Autor según el artículo: Bardají, A.; Leal, M.; Arrarte, V.; Garcia-Moll, X.; Pérez de Isla, L.; Bueno, H.
    Departamento: Medicina i Cirurgia
    Autor/es de la URV: BARDAJÍ RUIZ, ALFREDO; Leal, M.; Arrarte, V.; Garcia-Moll, X.; Pérez de Isla, L.; Bueno, H.
    Palabras clave: Coronary artery disease Acute coronary syndrome myocardial infarction
    Resumen: Introduction: Real-world, country-specific studies of dual antiplatelet therapy (DAPT) duration among survivors of acute coronary syndrome (ACS) are important for improving long-term prognosis. Aims: To investigate DAPT duration after hospital discharge for ACS in Spain. Results: Data from patients enrolled in the Spanish cohort of the EPICOR (long-tErm follow-up of antithrombotic management Patterns In acute CORonary syndrome patients) study (NCT01171404) were analyzed for changes to antithrombotic medication up to 2 years postdischarge according to index event diagnosis and patient characteristics. Deaths, coronary events, and bleeding events were analyzed over the same period. Overall, a high proportion of patients remained on DAPT at 2 years (53.1%). Among patients who experienced any on-treatment bleeding event, almost two-thirds remained on DAPT at the end of follow-up. Patients >65 years, diabetic, or those that were medically managed were more likely to continue with DAPT until 2 years following discharge. At 2 years, the incidence of bleeding events requiring hospitalization was low compared with the incidence of coronary events (1.4% vs 6.6%). There was a numerical reduction in coronary events, but no increase in bleeding events, with DAPT continuation compared with single antiplatelet therapy. Conclusions: More than half of patients in this unselected cohort study remained on DAPT at 2 years following discharge for ACS. Continuation with DAPT was greater among patients with additional cardiovascular risk factors, which suggests that treating physicians in Spain prioritizes ischemic risk reduction over bleeding risk in patients with ACS, according to patient's risk profile.
    Grupo de investigación: Grup de Recerca Biomèdica HJ23
    Áreas temáticas: Health sciences Ciencias de la salud Ciències de la salut
    Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 1755-5914
    Identificador del autor: N/D; N/D; N/D; N/D; N/D; N/D
    Fecha de alta del registro: 2017-03-28
    Volumen de revista: 35
    Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
    Enlace a la fuente original: https://onlinelibrary.wiley.com/doi/full/10.1111/1755-5922.12237
    URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
    DOI del artículo: 10.1111/1755-5922.12237
    Entidad: Universitat Rovira i Virgili
    Año de publicación de la revista: 2017
    Página inicial: Art.num. e12237
    Tipo de publicación: Article Artículo Article
  • Palabras clave:

    Infart de miocardi
    Artèries coronàries -- Malalties
    Malalties coronàries
    Coronary artery disease
    Acute coronary syndrome
    myocardial infarction
    Health sciences
    Ciencias de la salud
    Ciències de la salut
    1755-5914
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