Articles producció científica> Bioquímica i Biotecnologia

Roles of proanthocyanidin rich extracts in obesity

  • Datos identificativos

    Identificador: PC:3389
    Autores:
    Salvadó, MJ
    Resumen:
    Obesity is a multifactorial disorder involving an abnormal or excessive amount of body fat. Obese people have a very high probability of developing metabolic syndrome, a condition in which cholesterol, lipid, and glucose levels rise, causing diabetes and heart disease. From the point of view of energy balance, the main contributors to obesity are excessive energy intake, inadequate energy expenditure and metabolic malfunctions. For this reason, health organisations are working to implement policies and plans to promote healthy eating and active living. However, these measures have not yet proven sufficient to combat this worldwide epidemic; therefore, drugs and bioactive compounds are being investigated to complement the existing strategies. In the present review, we discuss the available data regarding the modulation of obesity by proanthocyanidin rich extracts. Because studies with human subjects are very scarce, we focus on studies using laboratory animals. The results of in vitro studies are included because, although they cannot be directly extrapolated to the biological effects of proanthocyanidin, they can reveal some mechanisms of action.
  • Otros:

    Autor según el artículo: Salvadó, MJ
    Departamento: Bioquímica i Biotecnologia
    Autor/es de la URV: SALVADÓ ROVIRA, MARIA JOSEPA
    Resumen: Obesity is a multifactorial disorder involving an abnormal or excessive amount of body fat. Obese people have a very high probability of developing metabolic syndrome, a condition in which cholesterol, lipid, and glucose levels rise, causing diabetes and heart disease. From the point of view of energy balance, the main contributors to obesity are excessive energy intake, inadequate energy expenditure and metabolic malfunctions. For this reason, health organisations are working to implement policies and plans to promote healthy eating and active living. However, these measures have not yet proven sufficient to combat this worldwide epidemic; therefore, drugs and bioactive compounds are being investigated to complement the existing strategies. In the present review, we discuss the available data regarding the modulation of obesity by proanthocyanidin rich extracts. Because studies with human subjects are very scarce, we focus on studies using laboratory animals. The results of in vitro studies are included because, although they cannot be directly extrapolated to the biological effects of proanthocyanidin, they can reveal some mechanisms of action.
    Grupo de investigación: Grup de Recerca en Nutrigenòmica
    Áreas temáticas: Bioquímica i biotecnologia Bioquímica y tecnología Biochemistry and technology
    Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 2042-6496
    Identificador del autor: 0000-0003-3883-3326
    Fecha de alta del registro: 2019-01-17
    Página final: 1071
    Volumen de revista: 2015
    Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
    Enlace a la fuente original: https://pubs.rsc.org/en/content/articlelanding/2015/FO/C4FO01035C#!divAbstract
    URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
    DOI del artículo: 10.1039/c4fo01035c
    Entidad: Universitat Rovira i Virgili
    Año de publicación de la revista: 2015
    Página inicial: 1053
    Tipo de publicación: Article Artículo Article
  • Palabras clave:

    Raïms--Ús terapèutic
    Proantocianidines
    Bioquímica i biotecnologia
    Bioquímica y tecnología
    Biochemistry and technology
    2042-6496
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