Autor según el artículo: Guasch-Ferre, Marta; Becerra-Tomas, Nerea; Ruiz-Canela, Miguel; Corella, Dolores; Schroeder, Helmut; Estruch, Ramon; Ros, Emilio; Aros, Fernando; Gomez-Gracia, Enrique; Fiol, Miquel; Serra-Majem, Lluis; Lapetra, Jose; Basora, Josep; Martin-Calvo, Nerea; Portoles, Olga; Fito, Montserrat; Hu, Frank B; Forga, Lluis; Salas-Salvado, Jordi
Departamento: Bioquímica i Biotecnologia; Medicina i Cirurgia
Autor/es de la URV: Basora Gallisa, Josep / Becerra Tomás, Nerea / Castro Salomó, Antoni / Salas Huetos, Albert / Salas Salvadó, Jorge
Palabras clave: Ω-3 fatty acids; Yogurt; Womens health; W-3 fatty acids; Type 2 diabetes; Saturated fat; Risk factors; Red meat; Randomized-trial; Prospective studies; Proportional hazards models; Predimed study; Omega-3 fatty acids; Monounsaturated fat; Middle aged; Metabolic syndrome; Men; Meat; Male; Insulin-resistance; Incidence; Impaired glucose-tolerance; Humans; Follow-up studies; Female; Feeding behavior; Fatty acids; Fat subtypes; Dose-response metaanalysis; Dietary fats; Dietary fat; Diet, mediterranean; Diabetes mellitus, type 2; Cohort; Cheese; Cardiovascular-disease; Cardiovascular diseases; Butter; Animals; Aged; ?-3 fatty acids; type 2 diabetes; saturated fat; predimed study; monounsaturated fat; fat subtypes; dietary fat
Resumen: Background: The associations between dietary fat and cardiovascular disease have been evaluated in several studies, but less is known about their influence on the risk of diabetes.Objective: We examined the associations between total fat, subtypes of dietary fat, and food sources rich in saturated fatty acids and the incidence of type 2 diabetes (T2D).Design: A prospective cohort analysis of 3349 individuals who were free of diabetes at baseline but were at high cardiovascular risk from the PREvención con DIeta MEDiterránea (PREDIMED) study was conducted. Detailed dietary information was assessed at baseline and yearly during the follow-up using a food frequency questionnaire. Multivariable Cox proportional hazards models were used to estimate T2D HRs and 95% CIs according to baseline and yearly updated fat intake.Results: We documented 266 incident cases during 4.3 y of follow-up. Baseline saturated and animal fat intake was not associated with the risk of T2D. After multivariable adjustment, participants in the highest quartile of updated intake of saturated and animal fat had a higher risk of diabetes than the lowest quartile (HR: 2.19; 95% CI: 1.28, 3.73; and P-trend = 0.01 compared with HR: 2.00; 95% CI: 1.29, 3.09; and P-trend < 0.01, respectively). In both the Mediterranean diet and control groups, participants in the highest quartile of updated animal fat intake had an ?2-fold higher risk of T2D than their counterparts in the lowest quartile. The consumption of 1 serving of butter and cheese was associated with a higher risk of diabetes, whereas whole-fat yogurt intake was associated with a lower risk.Conclusions: In a Mediterranean trial focused on dietary fat interventions, baseline intake of saturated and animal fat was not associated with T2D incidence, but the yearly updated intake of saturated and animal fat was associated with a higher risk of T2D. Cheese and butter intake was associated with a higher risk of T2D, whereas whole-fat yogurt intake was associated with a lower risk of T2D. This trial was registered at www.isrctn.com as ISRCTN35739639.© 2017 American Society for Nutrition.
Grupo de investigación: Alimentació, Nutrició, Creixement i Salut Mental
Áreas temáticas: Serviço social; Saúde coletiva; Odontología; Nutrition and dietetics; Nutrition & dietetics; Nutrição; Medicine (miscellaneous); Medicina iii; Medicina ii; Medicina i; General medicine; Enfermagem; Educação física; Ciências biológicas ii; Ciência de alimentos; Biotecnología
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 00029165
Direcció de correo del autor: josep.basora@urv.cat; albert.salas@urv.cat; nerea.becerra@urv.cat; josep.basora@urv.cat; antoni.castro@urv.cat; jordi.salas@urv.cat
Fecha de alta del registro: 2025-02-24
Versión del articulo depositado: info:eu-repo/semantics/acceptedVersion
Enlace a la fuente original: https://academic.oup.com/ajcn/article/105/3/723/4569701
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: American Journal Of Clinical Nutrition. 105 (3): 723-735
Referencia de l'ítem segons les normes APA: Guasch-Ferre, Marta; Becerra-Tomas, Nerea; Ruiz-Canela, Miguel; Corella, Dolores; Schroeder, Helmut; Estruch, Ramon; Ros, Emilio; Aros, Fernando; Gome (2017). Total and subtypes of dietary fat intake and risk of type 2 diabetes mellitus in the Prevencion con Dieta Mediterranea (PREDIMED) study. American Journal Of Clinical Nutrition, 105(3), 723-735. DOI: 10.3945/ajcn.116.142034
DOI del artículo: 10.3945/ajcn.116.142034
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2017
Tipo de publicación: Journal Publications
Repositori URV