Articles producció científica> Ciències Mèdiques Bàsiques

Frequency of nut consumption and mortality risk in the PREDIMED nutrition intervention trial

  • Datos identificativos

    Identificador: imarina:3091387
    Handle: https://hdl.handle.net/20.500.11797/imarina3091387
    Autores:
    Guasch-Ferre, MartaBullo, MonicaAngel Martinez-Gonzalez, MiguelRos, EmilioCorella, DoloresEstruch, RamonFito, MontserratAros, FernandoWaernberg, JuliaFiol, MiquelLapetra, JoseVinyoles, ErnestMaria Lamuela-Raventos, RosaSerra-Majem, LluisPinto, XavierRuiz-Gutierrez, ValentinaBasora, JosepSalas-Salvado, Jordi
    Resumen:
    Prospective studies in non-Mediterranean populations have consistently related increasing nut consumption to lower coronary heart disease mortality. A small protective effect on all-cause and cancer mortality has also been suggested. To examine the association between frequency of nut consumption and mortality in individuals at high cardiovascular risk from Spain, a Mediterranean country with a relatively high average nut intake per person.We evaluated 7,216 men and women aged 55 to 80 years randomized to 1 of 3 interventions (Mediterranean diets supplemented with nuts or olive oil and control diet) in the PREDIMED ('PREvención con DIeta MEDiterránea') study. Nut consumption was assessed at baseline and mortality was ascertained by medical records and linkage to the National Death Index. Multivariable-adjusted Cox regression and multivariable analyses with generalized estimating equation models were used to assess the association between yearly repeated measurements of nut consumption and mortality.During a median follow-up of 4.8 years, 323 total deaths, 81 cardiovascular deaths and 130 cancer deaths occurred. Nut consumption was associated with a significantly reduced risk of all-cause mortality (P for trend<0.05, all). Compared to non-consumers, subjects consuming nuts>3 servings/week (32% of the cohort) had a 39% lower mortality risk (hazard ratio (HR) 0.61; 95% CI 0.45 to 0.83). A similar protective effect against cardiovascular and cancer mortality was observed. Participants allocated to the Mediterranean diet with nuts group who consumed nuts>3 servings/week at baseline had the lowest total mortality risk (HR 0.37; 95% CI 0.22 to 0.66).Increased frequency of nut consumption was associated with a significantly reduced risk of mortality in a Mediterranean populatio

  • Otros:

    Autor según el artículo: Guasch-Ferre, Marta; Bullo, Monica; Angel Martinez-Gonzalez, Miguel; Ros, Emilio; Corella, Dolores; Estruch, Ramon; Fito, Montserrat; Aros, Fernando; Waernberg, Julia; Fiol, Miquel; Lapetra, Jose; Vinyoles, Ernest; Maria Lamuela-Raventos, Rosa; Serra-Majem, Lluis; Pinto, Xavier; Ruiz-Gutierrez, Valentina; Basora, Josep; Salas-Salvado, Jordi
    Departamento: Ciències Mèdiques Bàsiques Bioquímica i Biotecnologia
    Autor/es de la URV: Babio Sánchez, Nancy Elvira / Basora Gallisa, Josep / Bulló Bonet, Mònica / Cabre Vila, Juan Jose / Díaz López, Andres / Fernández Ballart, Joan Domènech / Salas Salvadó, Jorge
    Palabras clave: Predimed study Nuts Mortality Cardiovascular Cancer
    Resumen: Prospective studies in non-Mediterranean populations have consistently related increasing nut consumption to lower coronary heart disease mortality. A small protective effect on all-cause and cancer mortality has also been suggested. To examine the association between frequency of nut consumption and mortality in individuals at high cardiovascular risk from Spain, a Mediterranean country with a relatively high average nut intake per person.We evaluated 7,216 men and women aged 55 to 80 years randomized to 1 of 3 interventions (Mediterranean diets supplemented with nuts or olive oil and control diet) in the PREDIMED ('PREvención con DIeta MEDiterránea') study. Nut consumption was assessed at baseline and mortality was ascertained by medical records and linkage to the National Death Index. Multivariable-adjusted Cox regression and multivariable analyses with generalized estimating equation models were used to assess the association between yearly repeated measurements of nut consumption and mortality.During a median follow-up of 4.8 years, 323 total deaths, 81 cardiovascular deaths and 130 cancer deaths occurred. Nut consumption was associated with a significantly reduced risk of all-cause mortality (P for trend<0.05, all). Compared to non-consumers, subjects consuming nuts>3 servings/week (32% of the cohort) had a 39% lower mortality risk (hazard ratio (HR) 0.61; 95% CI 0.45 to 0.83). A similar protective effect against cardiovascular and cancer mortality was observed. Participants allocated to the Mediterranean diet with nuts group who consumed nuts>3 servings/week at baseline had the lowest total mortality risk (HR 0.37; 95% CI 0.22 to 0.66).Increased frequency of nut consumption was associated with a significantly reduced risk of mortality in a Mediterranean population at high cardiovascular risk.Please see related commentary: http://www.biomedcentral.com/1741-7015/11/165.Clinicaltrials.gov. International Standard Randomized Controlled Trial Number (ISRCTN): 35739639. Registration date: 5 October 2005.
    Áreas temáticas: Saúde coletiva Medicine, general & internal Medicine (miscellaneous) Medicine (all) Medicina veterinaria Medicina ii Medicina i General medicine Ciências biológicas iii Ciências biológicas ii Ciências biológicas i
    Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 17417015
    Direcció de correo del autor: juanjose.cabre@urv.cat josep.basora@urv.cat andres.diaz@urv.cat monica.bullo@urv.cat josep.basora@urv.cat jordi.salas@urv.cat nancy.babio@urv.cat
    Identificador del autor: 0000-0003-1082-6861 0000-0002-7500-5629 0000-0002-0218-7046 0000-0003-2700-7459 0000-0003-3527-5277
    Fecha de alta del registro: 2024-10-12
    Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
    Enlace a la fuente original: https://bmcmedicine.biomedcentral.com/articles/10.1186/1741-7015-11-164
    URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referencia al articulo segun fuente origial: Bmc Medicine. 11 (164): 164-
    Referencia de l'ítem segons les normes APA: Guasch-Ferre, Marta; Bullo, Monica; Angel Martinez-Gonzalez, Miguel; Ros, Emilio; Corella, Dolores; Estruch, Ramon; Fito, Montserrat; Aros, Fernando; (2013). Frequency of nut consumption and mortality risk in the PREDIMED nutrition intervention trial. Bmc Medicine, 11(164), 164-. DOI: 10.1186/1741-7015-11-164
    DOI del artículo: 10.1186/1741-7015-11-164
    Entidad: Universitat Rovira i Virgili
    Año de publicación de la revista: 2013
    Tipo de publicación: Journal Publications

  • Palabras clave:

    Medicine (Miscellaneous),Medicine, General & Internal
    Predimed study
    Nuts
    Mortality
    Cardiovascular
    Cancer
    Saúde coletiva
    Medicine, general & internal
    Medicine (miscellaneous)
    Medicine (all)
    Medicina veterinaria
    Medicina ii
    Medicina i
    General medicine
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i

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