Articles producció científica> Bioquímica i Biotecnologia

Inflammation, obesity and comorbidities: the role of diet

  • Datos identificativos

    Identificador: imarina:5118949
    Autores:
    Bullo, MonicaCasas-Agustench, PatriciaAmigo-Correig, PilarAranceta, JavierSalas-Salvado, Jordi
    Resumen:
    The adipocyte metabolism has been shown to change during the fat enlargement process associated to obesity. Several procoagulant proteins such as plasminogen activator inhibitor type 1, tissue factor or factor VII and also inducible nitric oxide synthase show higher expression in adipose tissue of obese people in comparison to lean. This overexpression could explain at least a part of the atherogenic and cardiovascular risk associated with obesity.In addition to cytokine secretion, many other features have been observed to be common to adipocyte and monocyte/macrophage lines: for example, phagocytic and microbicidal activities, and possibly a cellular plasticity of adipose precursors.Overweight and obesity are associated with an increased risk of such metabolic abnormalities as dyslipidemia, hypertension or type 2 diabetes mellitus and cardiovascular diseases, common features of the metabolic syndrome. Initially, insulin resistance or hyperinsulinemia was suggested as the origin of these abnormalities. More recent studies indicate that adipokynes have an important role in obesity-associated metabolic complications, and suggest that chronically elevated local or systemic concentrations of adipokynes contribute to the development of complications associated with obesity and metabolic syndrome.Considering all the evidence relating to diet and inflammation, the best diet for protecting against the metabolic derangements associated with obesity and metabolic syndrome would be high in fibre-rich cereals, fruit, vegetables, fish, virgin olive oil and nuts; moderate in wine; and low in meat, processed meat foods and trans-fatty acids. © 2007 The Authors.
  • Otros:

    Autor según el artículo: Bullo, Monica; Casas-Agustench, Patricia; Amigo-Correig, Pilar; Aranceta, Javier; Salas-Salvado, Jordi
    Departamento: Bioquímica i Biotecnologia
    Autor/es de la URV: Amigó Correig, Maria Pilar / Bulló Bonet, Mònica / CASAS AGUSTENCH, PATRICIA / Salas Salvadó, Jorge
    Palabras clave: Obesity Metabolic syndrome Inflammation Diet
    Resumen: The adipocyte metabolism has been shown to change during the fat enlargement process associated to obesity. Several procoagulant proteins such as plasminogen activator inhibitor type 1, tissue factor or factor VII and also inducible nitric oxide synthase show higher expression in adipose tissue of obese people in comparison to lean. This overexpression could explain at least a part of the atherogenic and cardiovascular risk associated with obesity.In addition to cytokine secretion, many other features have been observed to be common to adipocyte and monocyte/macrophage lines: for example, phagocytic and microbicidal activities, and possibly a cellular plasticity of adipose precursors.Overweight and obesity are associated with an increased risk of such metabolic abnormalities as dyslipidemia, hypertension or type 2 diabetes mellitus and cardiovascular diseases, common features of the metabolic syndrome. Initially, insulin resistance or hyperinsulinemia was suggested as the origin of these abnormalities. More recent studies indicate that adipokynes have an important role in obesity-associated metabolic complications, and suggest that chronically elevated local or systemic concentrations of adipokynes contribute to the development of complications associated with obesity and metabolic syndrome.Considering all the evidence relating to diet and inflammation, the best diet for protecting against the metabolic derangements associated with obesity and metabolic syndrome would be high in fibre-rich cereals, fruit, vegetables, fish, virgin olive oil and nuts; moderate in wine; and low in meat, processed meat foods and trans-fatty acids. © 2007 The Authors.
    Grupo de investigación: Alimentació, Nutrició, Creixement i Salut Mental
    Áreas temáticas: Sociologia i política Serviço social Saúde coletiva Public, environmental & occupational health Public health, environmental and occupational health Planejamento urbano e regional / demografia Odontología Nutrition and dietetics Nutrition & dietetics Nutrição Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Matemática / probabilidade e estatística Interdisciplinar General medicine Farmacia Engenharias iv Engenharias iii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciência de alimentos Biotecnología Biodiversidade Antropologia / arqueologia
    Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
    Direcció de correo del autor: mariapilar.amigo@urv.cat monica.bullo@urv.cat jordi.salas@urv.cat
    Identificador del autor: 0000-0002-0218-7046 0000-0003-2700-7459
    Fecha de alta del registro: 2024-10-12
    Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
    Enlace a la fuente original: https://www.cambridge.org/core/journals/public-health-nutrition/article/inflammation-obesity-and-comorbidities-the-role-of-diet/B0EC848A7E7D1007CFED5EEB223B80C5
    URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referencia al articulo segun fuente origial: Public Health Nutrition. 10 (10a): 1164-1172
    Referencia de l'ítem segons les normes APA: Bullo, Monica; Casas-Agustench, Patricia; Amigo-Correig, Pilar; Aranceta, Javier; Salas-Salvado, Jordi (2007). Inflammation, obesity and comorbidities: the role of diet. Public Health Nutrition, 10(10a), 1164-1172. DOI: 10.1017/S1368980007000663
    DOI del artículo: 10.1017/S1368980007000663
    Entidad: Universitat Rovira i Virgili
    Año de publicación de la revista: 2007
    Tipo de publicación: Journal Publications
  • Palabras clave:

    Medicine (Miscellaneous),Nutrition & Dietetics,Nutrition and Dietetics,Public Health, Environmental and Occupational Health,Public, Environmental & Occupational Health
    Obesity
    Metabolic syndrome
    Inflammation
    Diet
    Sociologia i política
    Serviço social
    Saúde coletiva
    Public, environmental & occupational health
    Public health, environmental and occupational health
    Planejamento urbano e regional / demografia
    Odontología
    Nutrition and dietetics
    Nutrition & dietetics
    Nutrição
    Medicine (miscellaneous)
    Medicina veterinaria
    Medicina iii
    Medicina ii
    Medicina i
    Matemática / probabilidade e estatística
    Interdisciplinar
    General medicine
    Farmacia
    Engenharias iv
    Engenharias iii
    Enfermagem
    Educação física
    Economia
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciência de alimentos
    Biotecnología
    Biodiversidade
    Antropologia / arqueologia
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