Autor según el artículo: Casanova-Marti, Angela; Serrano, Joan; Portune, Kevin J; Sanz, Yolanda; Teresa Blay, M; Terra, Ximena; Ardevol, Anna; Pinent, Montserrat
Departamento: Bioquímica i Biotecnologia
Autor/es de la URV: Ardévol Grau, Anna / Blay Olivé, Maria Teresa / CASANOVA MARTÍ, ANGELA / Pinent Armengol, Montserrat / Terra Barbadora, Ximena
Palabras clave: Rats, wistar Rats Proanthocyanidins Metabolic syndrome Humans Grape seed proanthocyanidins Grape seed extract Glucagon-like peptide 1 Gastrointestinal microbiome Gallic acid Female Butyrates Bacteria Animals Adiposity
Resumen: Grape seed proanthocyanidin extract (GSPE) modulates several parameters involved in metabolic syndrome. GSPE is a mixture of compounds, some which are rapidly absorbed, while others remain in the lumen where they might have effects that are translated to the whole organism. Our aim was to decipher if the 8-day treatment of GSPE, previously shown to reduce food intake, induces changes in the microbiota and enterohormone secretion. The ratio of Firmicutes?:?Bacteroidetes was lower in the microbiota of GSPE-treated rats compared to controls, and differences in several taxonomic families and genera were observed. Such modulation led to a reduction in cecal butyrate content. GSPE also increased plasma glucagon-like-peptide-1 (GLP-1). Gallic acid did not induce major changes in the microbiota profile nor in GLP-1 secretion. Correlations between several microbiota taxa and plasma triacylglycerol, adiposity, and enterohormones were observed. Modulation of microbiota may be one of the mechanism by which GSPE impacts metabolic health.
Áreas temáticas: Zootecnia / recursos pesqueiros Saúde coletiva Química Odontología Nutrição Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Food science & technology Food science Farmacia Educação física Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Biotecnología Biochemistry & molecular biology
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 29938270
Direcció de correo del autor: anna.ardevol@urv.cat ximena.terra@urv.cat mteresa.blay@urv.cat montserrat.pinent@urv.cat
Identificador del autor: 0000-0003-0156-7538 0000-0003-1043-5844 0000-0002-6256-9847 0000-0003-3550-5378
Fecha de alta del registro: 2024-10-19
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://pubs.rsc.org/en/content/articlelanding/2018/FO/C7FO02028G#!divAbstract
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Food & Function. 9 (3): 1672-1682
Referencia de l'ítem segons les normes APA: Casanova-Marti, Angela; Serrano, Joan; Portune, Kevin J; Sanz, Yolanda; Teresa Blay, M; Terra, Ximena; Ardevol, Anna; Pinent, Montserrat (2018). Grape seed proanthocyanidins influence gut microbiota and enteroendocrine secretions in female rats. Food & Function, 9(3), 1672-1682. DOI: 10.1039/c7fo02028g
DOI del artículo: 10.1039/c7fo02028g
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2018
Tipo de publicación: Journal Publications