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SET-LRP in Biphasic Mixtures of the Nondisproportionating Solvent Hexafluoroisopropanol with Water

  • Datos identificativos

    Identificador: imarina:5132963
    Autores:
    Moreno A, Galià M, Lligadas G, Percec V.
    Resumen:
    The fluorinated alcohol 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) is an especially effective solvent for solubilizing a wide range of polymers. However, the performance of HFIP as SET-LRP solvent has classically been questioned due to its poor Cu(I)X disproportionating properties. Taking advantage of the fast and quantitative disproportionation of Cu(I)X in water, SET-LRP in organic solvent/water mixtures rids the organic solvent of mediating this fundamental event. Here, the Cu(0) wire-catalyzed SET-LRP synthesis of well-defined poly(methyl acrylate)s and poly(butyl acrylate)s with narrow molecular weight distribution and near perfect bromine chain end functionality is reported in HFIP/water mixtures. The results reported here support the potential of HFIP/water mixtures in the preparation of more complex architectures including polymers with dual control over molecular weight and tacticity. Since HFIP is also a classic solvent for the denaturation of proteins this SET-LRP system is also expected to find applications in the grafting of protein.
  • Otros:

    Autor según el artículo: Moreno A, Galià M, Lligadas G, Percec V.
    Departamento: Química Analítica i Química Orgànica
    Autor/es de la URV: Galià Clua, Marina Teresa / Lligadas Puig, Gerard
    Palabras clave: Hashtag Etiqueta «#» @uroweb @residentesaeu @infoAeu
    Resumen: The fluorinated alcohol 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) is an especially effective solvent for solubilizing a wide range of polymers. However, the performance of HFIP as SET-LRP solvent has classically been questioned due to its poor Cu(I)X disproportionating properties. Taking advantage of the fast and quantitative disproportionation of Cu(I)X in water, SET-LRP in organic solvent/water mixtures rids the organic solvent of mediating this fundamental event. Here, the Cu(0) wire-catalyzed SET-LRP synthesis of well-defined poly(methyl acrylate)s and poly(butyl acrylate)s with narrow molecular weight distribution and near perfect bromine chain end functionality is reported in HFIP/water mixtures. The results reported here support the potential of HFIP/water mixtures in the preparation of more complex architectures including polymers with dual control over molecular weight and tacticity. Since HFIP is also a classic solvent for the denaturation of proteins this SET-LRP system is also expected to find applications in the grafting of protein.
    Áreas temáticas: Química Polymers and plastics Polymer science Medicina ii Materials chemistry Materiais Interdisciplinar Farmacia Engenharias iv Engenharias ii Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Chemistry, organic Biotecnología Biomaterials Bioengineering Biochemistry & molecular biology Astronomia / física
    ISSN: 15257797
    Direcció de correo del autor: marina.galia@urv.cat gerard.lligadas@urv.cat
    Identificador del autor: 0000-0002-4359-4510 0000-0002-8519-1840
    Página final: 4491
    Fecha de alta del registro: 2024-09-07
    Volumen de revista: 19
    Versión del articulo depositado: info:eu-repo/semantics/acceptedVersion
    Enlace a la fuente original: https://pubs.acs.org/doi/10.1021/acs.biomac.8b01381
    URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referencia al articulo segun fuente origial: Biomacromolecules. 19 (11): 4480-4491
    Referencia de l'ítem segons les normes APA: Moreno A, Galià M, Lligadas G, Percec V. (2018). SET-LRP in Biphasic Mixtures of the Nondisproportionating Solvent Hexafluoroisopropanol with Water. Biomacromolecules, 19(11), 4480-4491. DOI: 10.1021/acs.biomac.8b01381
    DOI del artículo: 10.1021/acs.biomac.8b01381
    Entidad: Universitat Rovira i Virgili
    Año de publicación de la revista: 2018
    Página inicial: 4480
    Tipo de publicación: Journal Publications
  • Palabras clave:

    Biochemistry & Molecular Biology,Bioengineering,Biomaterials,Chemistry, Organic,Materials Chemistry,Polymer Science,Polymers and Plastics
    Química
    Polymers and plastics
    Polymer science
    Medicina ii
    Materials chemistry
    Materiais
    Interdisciplinar
    Farmacia
    Engenharias iv
    Engenharias ii
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências agrárias i
    Ciência de alimentos
    Chemistry, organic
    Biotecnología
    Biomaterials
    Bioengineering
    Biochemistry & molecular biology
    Astronomia / física
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