Autor según el artículo: Tresserra-Rimbau A; Castro-Barquero S; Vitelli-Storelli F; Becerra-Tomas N; Vázquez-Ruiz Z; Díaz-López A; Corella D; Castañer O; Romaguera D; Vioque J; Alonso-Gómez ÁM; Wärnberg J; Martínez JA; Serra-Majem L; Estruch R; Tinahones FJ; Lapetra J; Pintó X; Tur JA; López-Miranda J; García-Molina L; Delgado-Rodríguez M; Matía-Martín P; Daimiel L; Rubín-García M; Vidal J; Galdon A; Ros E; Basterra-Gortari FJ; Babio N; Sorlí JV; Hernáez Á; Konieczna J; Notario-Barandiaran L; Tojal-Sierra L; Pérez-López J; Abete I; Álvarez-Pérez J; Fernández-García JC; Santos-Lozano JM; Galera-Cusí A; Julibert A; Ruiz-Canela M; Martínez-Lacruz R; Pérez-Vega KA; Galmes-Panades AM; Pastor-Polo C; Moreno-Rodríguez A; Gea A; Fitó M; Lamuela-Raventós RM; Salas-Salvadó J

Departamento: Bioquímica i Biotecnologia

e-ISSN: 2076-3921

Autor/es de la URV: Babio Sánchez, Nancy Elvira / Becerra Tomás, Nerea / Díaz López, Andres / Salas Salvadó, Jorge

Palabras clave: Proanthocyanidins Phenolic acids Obesity Lignans Hydroxycinnamic acids Hydroxybenzoic acids Flavonoids Diet Catechins

Resumen: © 2019 by the authors. Licensee MDPI, Basel, Switzerland. Overweight and obesity are important risk factors for type 2 diabetes (T2D). Moving towards healthier diets, namely, diets rich in bioactive compounds, could decrease the odds of suffering T2D. However, those individuals with high body mass index (BMI) may have altered absorption or metabolism of some nutrients and dietary components, including polyphenols. Therefore, we aimed to assess whether high intakes of some classes of polyphenols are associated with T2D in a population with metabolic syndrome and how these associations depend on BMI and sex. This baseline cross-sectional analysis includes 6633 participants from the PREDIMED-Plus trial. Polyphenol intakes were calculated from food frequency questionnaires (FFQ). Cox regression models with constant time at risk and robust variance estimators were used to estimate the prevalence ratios (PRs) for polyphenol intake and T2D prevalence using the lowest quartile as the reference group. Analyses were stratified by sex and BMI groups (overweight and obese) to evaluate potential effect modification. Catechins, proanthocyanidins, hydroxybenzoic acids, and lignans were inversely associated with T2D. Hydroxycinnamic acids were directly related in men. These associations were different depending on sex and BMI, that is, women and overweight obtained stronger inverse associations.

Áreas temáticas: Química Physiology Molecular biology Medicina ii Medicina i Interdisciplinar Food science & technology Food science Farmacia Engenharias ii Clinical biochemistry Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Chemistry, medicinal Cell biology Biotecnología Biodiversidade Biochemistry & molecular biology Biochemistry

Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 20763921

Direcció de correo del autor: nerea.becerra@urv.cat andres.diaz@urv.cat nancy.babio@urv.cat jordi.salas@urv.cat

Identificador del autor: 0000-0002-4429-6507 0000-0002-7500-5629 0000-0003-3527-5277 0000-0003-2700-7459

Fecha de alta del registro: 2023-07-31

Volumen de revista: 8

Versión del articulo depositado: info:eu-repo/semantics/publishedVersion

Enlace a la fuente original: https://www.mdpi.com/2076-3921/8/11/537

URL Documento de licencia: http://repositori.urv.cat/ca/proteccio-de-dades/

Referencia al articulo segun fuente origial: Antioxidants. 8 (11): 537-

Referencia de l'ítem segons les normes APA: Tresserra-Rimbau A; Castro-Barquero S; Vitelli-Storelli F; Becerra-Tomas N; Vázquez-Ruiz Z; Díaz-López A; Corella D; Castañer O; Romaguera D; Vioque J (2019). Associations between dietary polyphenols and type 2 diabetes in a cross-sectional analysis of the PREDIMED-Plus trial: Role of body mass index and sex. Antioxidants, 8(11), 537-. DOI: 10.3390/antiox8110537

DOI del artículo: 10.3390/antiox8110537

Entidad: Universitat Rovira i Virgili

Año de publicación de la revista: 2019

Tipo de publicación: Journal Publications