Autor según el artículo: Tresserra-Rimbau A; Castro-Barquero S; Vitelli-Storelli F; Becerra-Tomas N; Vázquez-Ruiz Z; Díaz-López A; Corella D; Castañer O; Romaguera D; Vioque J; Alonso-Gómez ÁM; Wärnberg J; Martínez JA; Serra-Majem L; Estruch R; Tinahones FJ; Lapetra J; Pintó X; Tur JA; López-Miranda J; García-Molina L; Delgado-Rodríguez M; Matía-Martín P; Daimiel L; Rubín-García M; Vidal J; Galdon A; Ros E; Basterra-Gortari FJ; Babio N; Sorlí JV; Hernáez Á; Konieczna J; Notario-Barandiaran L; Tojal-Sierra L; Pérez-López J; Abete I; Álvarez-Pérez J; Fernández-García JC; Santos-Lozano JM; Galera-Cusí A; Julibert A; Ruiz-Canela M; Martínez-Lacruz R; Pérez-Vega KA; Galmes-Panades AM; Pastor-Polo C; Moreno-Rodríguez A; Gea A; Fitó M; Lamuela-Raventós RM; Salas-Salvadó J
Departamento: Bioquímica i Biotecnologia
e-ISSN: 2076-3921
Autor/es de la URV: Babio Sánchez, Nancy Elvira / Becerra Tomás, Nerea / Díaz López, Andres / Salas Salvadó, Jorge
Palabras clave: Catechins Diet Flavonoids Hydroxybenzoic acids Hydroxycinnamic acids Lignans Obesity Phenolic acids Proanthocyanidins
Resumen: © 2019 by the authors. Licensee MDPI, Basel, Switzerland. Overweight and obesity are important risk factors for type 2 diabetes (T2D). Moving towards healthier diets, namely, diets rich in bioactive compounds, could decrease the odds of suffering T2D. However, those individuals with high body mass index (BMI) may have altered absorption or metabolism of some nutrients and dietary components, including polyphenols. Therefore, we aimed to assess whether high intakes of some classes of polyphenols are associated with T2D in a population with metabolic syndrome and how these associations depend on BMI and sex. This baseline cross-sectional analysis includes 6633 participants from the PREDIMED-Plus trial. Polyphenol intakes were calculated from food frequency questionnaires (FFQ). Cox regression models with constant time at risk and robust variance estimators were used to estimate the prevalence ratios (PRs) for polyphenol intake and T2D prevalence using the lowest quartile as the reference group. Analyses were stratified by sex and BMI groups (overweight and obese) to evaluate potential effect modification. Catechins, proanthocyanidins, hydroxybenzoic acids, and lignans were inversely associated with T2D. Hydroxycinnamic acids were directly related in men. These associations were different depending on sex and BMI, that is, women and overweight obtained stronger inverse associations.
Áreas temáticas: Biochemistry Biochemistry & molecular biology Biodiversidade Biotecnología Cell biology Chemistry, medicinal Ciência de alimentos Ciências agrárias i Ciências ambientais Ciências biológicas i Ciências biológicas ii Clinical biochemistry Engenharias ii Farmacia Food science Food science & technology Interdisciplinar Medicina i Medicina ii Molecular biology Physiology Química
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: jordi.salas@urv.cat nancy.babio@urv.cat andres.diaz@urv.cat nerea.becerra@urv.cat
ISSN: 20763921
Identificador del autor: 0000-0003-2700-7459 0000-0003-3527-5277 0000-0002-7500-5629 0000-0002-4429-6507
Fecha de alta del registro: 2023-07-31
Volumen de revista: 8
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://www.mdpi.com/2076-3921/8/11/537
Referencia al articulo segun fuente origial: Antioxidants. 8 (11): 537-
Referencia de l'ítem segons les normes APA: Tresserra-Rimbau A; Castro-Barquero S; Vitelli-Storelli F; Becerra-Tomas N; Vázquez-Ruiz Z; Díaz-López A; Corella D; Castañer O; Romaguera D; Vioque J (2019). Associations between dietary polyphenols and type 2 diabetes in a cross-sectional analysis of the PREDIMED-Plus trial: Role of body mass index and sex. Antioxidants, 8(11), 537-. DOI: 10.3390/antiox8110537
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
DOI del artículo: 10.3390/antiox8110537
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2019
Tipo de publicación: Journal Publications