Autor según el artículo: González-Quilen C; Rodríguez-Gallego E; Beltrán-Debón R; Pinent M; Ardévol A; Blay M; Terra X

Departamento: Bioquímica i Biotecnologia

Autor/es de la URV: Ardèvol Grau, Anna / Beltrán Debón, Raúl Alejandro / Blay Olivé, Maria Teresa / GONZALEZ QUILEN, CARLOS ALBERTO / Pinent Armengol, Montserrat / Rodríguez Gallego, Esther / Terra Barbadora, Ximena

Palabras clave: Ulcerative-colitis Signal-transduction pathways Procyanidin Permeability Oxidative stress Obesity Nf-kappa-b Metabolic endotoxemia Inflammatory-bowel-disease Inflammation In-vitro Ibd Gut microbiota Gut Grape seed extract Food sources Flavonoid Flavan-3-ol Dietary polyphenols Condensed tannin permeability obesity metabolic endotoxemia inflammation ibd gut flavonoid flavan-3-ol condensed tannin

Resumen: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. The intestinal barrier is constantly exposed to potentially harmful environmental factors, including food components and bacterial endotoxins. When intestinal barrier function and immune homeostasis are compromised (intestinal dysfunction), inflammatory conditions may develop and impact overall health. Evidence from experimental animal and cell culture studies suggests that exposure of intestinal mucosa to proanthocyanidin (PAC)-rich plant products, such as grape seeds, may contribute to maintaining the barrier function and to ameliorating the pathological inflammation present in diet-induced obesity and inflammatory bowel disease. In this review, we aim to update the current knowledge on the bioactivity of PACs in experimental models of intestinal dysfunction and in humans, and to provide insights into the underlying biochemical and molecular mechanisms.

Áreas temáticas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología

Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 20726643

Direcció de correo del autor: ximena.terra@urv.cat raul.beltran@urv.cat montserrat.pinent@urv.cat esther.rodriguez@urv.cat mteresa.blay@urv.cat anna.ardevol@urv.cat

Identificador del autor: 0000-0003-1043-5844 0000-0001-9691-1906 0000-0003-3550-5378 0000-0002-6256-9847 0000-0003-0156-7538

Fecha de alta del registro: 2023-06-09

Volumen de revista: 12

Versión del articulo depositado: info:eu-repo/semantics/publishedVersion

Enlace a la fuente original: https://www.mdpi.com/2072-6643/12/1/130

URL Documento de licencia: http://repositori.urv.cat/ca/proteccio-de-dades/

Referencia al articulo segun fuente origial: Nutrients. 12 (1):

Referencia de l'ítem segons les normes APA: González-Quilen C; Rodríguez-Gallego E; Beltrán-Debón R; Pinent M; Ardévol A; Blay M; Terra X (2020). Health-promoting properties of proanthocyanidins for intestinal dysfunction. Nutrients, 12(1), -. DOI: 10.3390/nu12010130

DOI del artículo: 10.3390/nu12010130

Entidad: Universitat Rovira i Virgili

Año de publicación de la revista: 2020

Tipo de publicación: Journal Publications