Autor según el artículo: Gonzalez-Quilen, Carlos; Rodriguez-Gallego, Esther; Beltran-Debon, Raul; Pinent, Montserrat; Ardevol, Anna; Teresa Blay, M; Terra, Ximena
Departamento: Bioquímica i Biotecnologia
Autor/es de la URV: Ardévol Grau, Anna / Beltrán Debón, Raúl Alejandro / Blay Olivé, Maria Teresa / GONZALEZ QUILEN, CARLOS ALBERTO / Pinent Armengol, Montserrat / Rodríguez Gallego, Esther / Terra Barbadora, Ximena
Palabras clave: Ulcerative-colitis; Signal-transduction pathways; Procyanidin; Proanthocyanidins; Phytochemicals; Permeability; Oxidative stress; Obesity; Nf-kappa-b; Metabolic endotoxemia; Inflammatory-bowel-disease; Inflammatory bowel diseases; Inflammation; In-vitro; Ibd; Humans; Gut microbiota; Gut; Grape seed extract; Food sources; Flavonoid; Flavan-3-ol; Dietary polyphenols; Condensed tannin; Animals; permeability; obesity; metabolic endotoxemia; inflammation; ibd; gut; flavonoid; flavan-3-ol; condensed tannin
Resumen: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. The intestinal barrier is constantly exposed to potentially harmful environmental factors, including food components and bacterial endotoxins. When intestinal barrier function and immune homeostasis are compromised (intestinal dysfunction), inflammatory conditions may develop and impact overall health. Evidence from experimental animal and cell culture studies suggests that exposure of intestinal mucosa to proanthocyanidin (PAC)-rich plant products, such as grape seeds, may contribute to maintaining the barrier function and to ameliorating the pathological inflammation present in diet-induced obesity and inflammatory bowel disease. In this review, we aim to update the current knowledge on the bioactivity of PACs in experimental models of intestinal dysfunction and in humans, and to provide insights into the underlying biochemical and molecular mechanisms.
Áreas temáticas: Zootecnia / recursos pesqueiros; Saúde coletiva; Química; Psicología; Planejamento urbano e regional / demografia; Nutrition and dietetics; Nutrition & dietetics; Nutrição; Medicina veterinaria; Medicina iii; Medicina ii; Medicina i; Interdisciplinar; Food science; Farmacia; Engenharias iv; Engenharias ii; Enfermagem; Educação física; Economia; Ciências biológicas iii; Ciências biológicas ii; Ciências biológicas i; Ciências agrárias i; Ciência de alimentos; Biotecnología
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 20726643
Direcció de correo del autor: anna.ardevol@urv.cat; ximena.terra@urv.cat; mteresa.blay@urv.cat; esther.rodriguez@urv.cat; montserrat.pinent@urv.cat; raul.beltran@urv.cat
Fecha de alta del registro: 2024-10-19
Volumen de revista: 12
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://www.mdpi.com/2072-6643/12/1/130
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Nutrients. 12 (1): E130-
Referencia de l'ítem segons les normes APA: Gonzalez-Quilen, Carlos; Rodriguez-Gallego, Esther; Beltran-Debon, Raul; Pinent, Montserrat; Ardevol, Anna; Teresa Blay, M; Terra, Ximena (2020). Health-promoting properties of proanthocyanidins for intestinal dysfunction. Nutrients, 12(1), E130-. DOI: 10.3390/nu12010130
DOI del artículo: 10.3390/nu12010130
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2020
Tipo de publicación: Journal Publications
Repositori URV