Autor según el artículo: Gonzalez-Quilen, Carlos; Rodriguez-Gallego, Esther; Beltran-Debon, Raul; Pinent, Montserrat; Ardevol, Anna; Teresa Blay, M; Terra, Ximena
Departamento: Bioquímica i Biotecnologia
Autor/es de la URV: Ardévol Grau, Anna / Beltrán Debón, Raúl Alejandro / Blay Olivé, Maria Teresa / GONZALEZ QUILEN, CARLOS ALBERTO / Pinent Armengol, Montserrat / Rodríguez Gallego, Esther / Terra Barbadora, Ximena
Palabras clave: Ulcerative-colitis Signal-transduction pathways Procyanidin Proanthocyanidins Phytochemicals Permeability Oxidative stress Obesity Nf-kappa-b Metabolic endotoxemia Inflammatory-bowel-disease Inflammatory bowel diseases Inflammation In-vitro Ibd Humans Gut microbiota Gut Grape seed extract Food sources Flavonoid Flavan-3-ol Dietary polyphenols Condensed tannin Animals permeability obesity metabolic endotoxemia inflammation ibd gut flavonoid flavan-3-ol condensed tannin
Resumen: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. The intestinal barrier is constantly exposed to potentially harmful environmental factors, including food components and bacterial endotoxins. When intestinal barrier function and immune homeostasis are compromised (intestinal dysfunction), inflammatory conditions may develop and impact overall health. Evidence from experimental animal and cell culture studies suggests that exposure of intestinal mucosa to proanthocyanidin (PAC)-rich plant products, such as grape seeds, may contribute to maintaining the barrier function and to ameliorating the pathological inflammation present in diet-induced obesity and inflammatory bowel disease. In this review, we aim to update the current knowledge on the bioactivity of PACs in experimental models of intestinal dysfunction and in humans, and to provide insights into the underlying biochemical and molecular mechanisms.
Áreas temáticas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 20726643
Direcció de correo del autor: anna.ardevol@urv.cat ximena.terra@urv.cat mteresa.blay@urv.cat esther.rodriguez@urv.cat montserrat.pinent@urv.cat raul.beltran@urv.cat
Identificador del autor: 0000-0003-0156-7538 0000-0003-1043-5844 0000-0002-6256-9847 0000-0003-3550-5378 0000-0001-9691-1906
Fecha de alta del registro: 2024-10-19
Volumen de revista: 12
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Nutrients. 12 (1): E130-
Referencia de l'ítem segons les normes APA: Gonzalez-Quilen, Carlos; Rodriguez-Gallego, Esther; Beltran-Debon, Raul; Pinent, Montserrat; Ardevol, Anna; Teresa Blay, M; Terra, Ximena (2020). Health-promoting properties of proanthocyanidins for intestinal dysfunction. Nutrients, 12(1), E130-. DOI: 10.3390/nu12010130
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2020
Tipo de publicación: Journal Publications
Repositori URV