Articles producció científica> Bioquímica i Biotecnologia

Health-promoting properties of proanthocyanidins for intestinal dysfunction

  • Datos identificativos

    Identificador: imarina:6063468
    Autores:
    Gonzalez-Quilen, CarlosRodriguez-Gallego, EstherBeltran-Debon, RaulPinent, MontserratArdevol, AnnaTeresa Blay, MTerra, Ximena
    Resumen:
    © 2020 by the authors. Licensee MDPI, Basel, Switzerland. The intestinal barrier is constantly exposed to potentially harmful environmental factors, including food components and bacterial endotoxins. When intestinal barrier function and immune homeostasis are compromised (intestinal dysfunction), inflammatory conditions may develop and impact overall health. Evidence from experimental animal and cell culture studies suggests that exposure of intestinal mucosa to proanthocyanidin (PAC)-rich plant products, such as grape seeds, may contribute to maintaining the barrier function and to ameliorating the pathological inflammation present in diet-induced obesity and inflammatory bowel disease. In this review, we aim to update the current knowledge on the bioactivity of PACs in experimental models of intestinal dysfunction and in humans, and to provide insights into the underlying biochemical and molecular mechanisms.
  • Otros:

    Autor según el artículo: Gonzalez-Quilen, Carlos; Rodriguez-Gallego, Esther; Beltran-Debon, Raul; Pinent, Montserrat; Ardevol, Anna; Teresa Blay, M; Terra, Ximena
    Departamento: Bioquímica i Biotecnologia
    Autor/es de la URV: Ardévol Grau, Anna / Beltrán Debón, Raúl Alejandro / Blay Olivé, Maria Teresa / GONZALEZ QUILEN, CARLOS ALBERTO / Pinent Armengol, Montserrat / Rodríguez Gallego, Esther / Terra Barbadora, Ximena
    Palabras clave: Ulcerative-colitis Signal-transduction pathways Procyanidin Proanthocyanidins Phytochemicals Permeability Oxidative stress Obesity Nf-kappa-b Metabolic endotoxemia Inflammatory-bowel-disease Inflammatory bowel diseases Inflammation In-vitro Ibd Humans Gut microbiota Gut Grape seed extract Food sources Flavonoid Flavan-3-ol Dietary polyphenols Condensed tannin Animals permeability obesity metabolic endotoxemia inflammation ibd gut flavonoid flavan-3-ol condensed tannin
    Resumen: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. The intestinal barrier is constantly exposed to potentially harmful environmental factors, including food components and bacterial endotoxins. When intestinal barrier function and immune homeostasis are compromised (intestinal dysfunction), inflammatory conditions may develop and impact overall health. Evidence from experimental animal and cell culture studies suggests that exposure of intestinal mucosa to proanthocyanidin (PAC)-rich plant products, such as grape seeds, may contribute to maintaining the barrier function and to ameliorating the pathological inflammation present in diet-induced obesity and inflammatory bowel disease. In this review, we aim to update the current knowledge on the bioactivity of PACs in experimental models of intestinal dysfunction and in humans, and to provide insights into the underlying biochemical and molecular mechanisms.
    Áreas temáticas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología
    Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 20726643
    Direcció de correo del autor: anna.ardevol@urv.cat ximena.terra@urv.cat mteresa.blay@urv.cat esther.rodriguez@urv.cat montserrat.pinent@urv.cat raul.beltran@urv.cat
    Identificador del autor: 0000-0003-0156-7538 0000-0003-1043-5844 0000-0002-6256-9847 0000-0003-3550-5378 0000-0001-9691-1906
    Fecha de alta del registro: 2024-10-19
    Volumen de revista: 12
    Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
    Enlace a la fuente original: https://www.mdpi.com/2072-6643/12/1/130
    URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referencia al articulo segun fuente origial: Nutrients. 12 (1): E130-
    Referencia de l'ítem segons les normes APA: Gonzalez-Quilen, Carlos; Rodriguez-Gallego, Esther; Beltran-Debon, Raul; Pinent, Montserrat; Ardevol, Anna; Teresa Blay, M; Terra, Ximena (2020). Health-promoting properties of proanthocyanidins for intestinal dysfunction. Nutrients, 12(1), E130-. DOI: 10.3390/nu12010130
    DOI del artículo: 10.3390/nu12010130
    Entidad: Universitat Rovira i Virgili
    Año de publicación de la revista: 2020
    Tipo de publicación: Journal Publications
  • Palabras clave:

    Food Science,Nutrition & Dietetics,Nutrition and Dietetics
    Ulcerative-colitis
    Signal-transduction pathways
    Procyanidin
    Proanthocyanidins
    Phytochemicals
    Permeability
    Oxidative stress
    Obesity
    Nf-kappa-b
    Metabolic endotoxemia
    Inflammatory-bowel-disease
    Inflammatory bowel diseases
    Inflammation
    In-vitro
    Ibd
    Humans
    Gut microbiota
    Gut
    Grape seed extract
    Food sources
    Flavonoid
    Flavan-3-ol
    Dietary polyphenols
    Condensed tannin
    Animals
    permeability
    obesity
    metabolic endotoxemia
    inflammation
    ibd
    gut
    flavonoid
    flavan-3-ol
    condensed tannin
    Zootecnia / recursos pesqueiros
    Saúde coletiva
    Química
    Psicología
    Planejamento urbano e regional / demografia
    Nutrition and dietetics
    Nutrition & dietetics
    Nutrição
    Medicina veterinaria
    Medicina iii
    Medicina ii
    Medicina i
    Interdisciplinar
    Food science
    Farmacia
    Engenharias iv
    Engenharias ii
    Enfermagem
    Educação física
    Economia
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências agrárias i
    Ciência de alimentos
    Biotecnología
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