Autor según el artículo: Mayneris-Perxachs, Jordi; Sala-Vila, Aleix; Chisaguano, Maribel; Castellote, Ana I.; Estruch, Ramon; Isabel Covas, Maria; Fito, Montserrat; Salas-Salvado, Jordi; Martinez-Gonzalez, Miguel A.; Lamuela-Raventos, Rosa; Ros, Emilio; Carmen Lopez-Sabater, M.; PREDIMED Study Investigators
Departamento: Ciències Mèdiques Bàsiques Bioquímica i Biotecnologia
Autor/es de la URV: Bulló Bonet, Mònica / Díaz López, Andres / Fernández Ballart, Joan Domènech / Salas Salvadó, Jorge
Palabras clave: Fatty acid Cholesterol Cardiovascular diseases
Resumen: Metabolic syndrome (MetS) has become an important public concern due to its increasing prevalence. An altered fatty acid composition has been associated with MetS, but the Mediterranean diet has been shown to have a protective effect. The aim of the present study was to analyze the influence of a Mediterranean dietary pattern, as assessed by the biomarkers of food supplied, on the plasma fatty acid composition and its relation with MetS after 1 year of intervention.A total of 424 subjects were randomly selected from the PREDIMED randomized dietary trial after completing a 1-year intervention program. Participants aged 55 to 80 years and at high risk of cardiovascular disease were randomly assigned to three dietary interventions: Mediterranean diet supplemented with virgin olive oil or nuts, or a low-fat diet.After 1 year of intervention participants in the virgin olive oil group showed significantly increased plasma concentrations of palmitic and oleic acids, but reduced proportions of margaric, stearic, and linoleic acids. In turn, subjects in the nut group showed significantly increased levels of palmitic, linoleic, and ?-linolenic acids, but reduced proportions of myristic, margaric, palmitoleic, and dihommo-?-linoleic acids. Increases in the biomarkers of foods supplied to the Mediterranean diet groups, i.e., oleic and ?-linolenic acids, were beneficially associated with the incidence, reversion and prevalence of MetS. No weight changes were observed among participants.The nut and olive oil diets induced a fatty acid composition that has been shown to be beneficial in the face of MetS. Therefore, a Mediterranean diet rich in fats of vegetable origin may be a useful tool for the management of MetS without the need for concerns over weight gain due to its high fat content.Controlled-Trials.com ISRCTN35739639.
Áreas temáticas: Zootecnia / recursos pesqueiros Sociology Sociología Serviço social Saúde coletiva Química Psychology Psicología Planejamento urbano e regional / demografia Odontología Nutrição Multidisciplinary sciences Multidisciplinary Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Matemática / probabilidade e estatística Linguística e literatura Letras / linguística Interdisciplinary research in the social sciences Interdisciplinar Human geography and urban studies History & philosophy of science Historia Geografía Geociências General medicine General biochemistry,genetics and molecular biology General agricultural and biological sciences Farmacia Environmental studies Ensino Engenharias iv Engenharias iii Engenharias ii Engenharias i Enfermagem Educação física Educação Economia Direito Demography Comunicação e informação Ciências sociais aplicadas i Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência política e relações internacionais Ciência de alimentos Ciência da computação Biotecnología Biology Biodiversidade Biochemistry, genetics and molecular biology (miscellaneous) Astronomia / física Arquitetura, urbanismo e design Archaeology Antropologia / arqueologia Anthropology Agricultural and biological sciences (miscellaneous) Administração, ciências contábeis e turismo Administração pública e de empresas, ciências contábeis e turismo
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 19326203
Direcció de correo del autor: andres.diaz@urv.cat monica.bullo@urv.cat jordi.salas@urv.cat
Identificador del autor: 0000-0002-7500-5629 0000-0002-0218-7046 0000-0003-2700-7459
Fecha de alta del registro: 2024-09-07
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0085202
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Plos One. 9 (3): e85202-e85202
Referencia de l'ítem segons les normes APA: Mayneris-Perxachs, Jordi; Sala-Vila, Aleix; Chisaguano, Maribel; Castellote, Ana I.; Estruch, Ramon; Isabel Covas, Maria; Fito, Montserrat; Salas-Salv (2014). Effects of 1-year intervention with a mediterranean diet on plasma Fatty Acid composition and metabolic syndrome in a population at high cardiovascular risk. Plos One, 9(3), e85202-e85202. DOI: 10.1371/journal.pone.0085202
DOI del artículo: 10.1371/journal.pone.0085202
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2014
Tipo de publicación: Journal Publications
Repositori URV