Effects of 1-year intervention with a mediterranean diet on plasma Fatty Acid composition and metabolic syndrome in a population at high cardiovascular risk

Autor según el artículo: Mayneris-Perxachs, Jordi; Sala-Vila, Aleix; Chisaguano, Maribel; Castellote, Ana I; Estruch, Ramon; Isabel Covas, Maria; Fito, Montserrat; Salas-Salvado, Jordi; Martinez-Gonzalez, Miguel A; Lamuela-Raventos, Rosa; Ros, Emilio; Carmen Lopez-Sabater, M

Departamento: Ciències Mèdiques Bàsiques; Bioquímica i Biotecnologia

Autor/es de la URV: Bulló Bonet, Mònica / Díaz López, Andres / Fernández Ballart, Joan Domènech / Salas Salvadó, Jorge

Palabras clave: Fatty acid; Cholesterol; Cardiovascular diseases

Resumen: Metabolic syndrome (MetS) has become an important public concern due to its increasing prevalence. An altered fatty acid composition has been associated with MetS, but the Mediterranean diet has been shown to have a protective effect. The aim of the present study was to analyze the influence of a Mediterranean dietary pattern, as assessed by the biomarkers of food supplied, on the plasma fatty acid composition and its relation with MetS after 1 year of intervention.A total of 424 subjects were randomly selected from the PREDIMED randomized dietary trial after completing a 1-year intervention program. Participants aged 55 to 80 years and at high risk of cardiovascular disease were randomly assigned to three dietary interventions: Mediterranean diet supplemented with virgin olive oil or nuts, or a low-fat diet.After 1 year of intervention participants in the virgin olive oil group showed significantly increased plasma concentrations of palmitic and oleic acids, but reduced proportions of margaric, stearic, and linoleic acids. In turn, subjects in the nut group showed significantly increased levels of palmitic, linoleic, and ?-linolenic acids, but reduced proportions of myristic, margaric, palmitoleic, and dihommo-?-linoleic acids. Increases in the biomarkers of foods supplied to the Mediterranean diet groups, i.e., oleic and ?-linolenic acids, were beneficially associated with the incidence, reversion and prevalence of MetS. No weight changes were observed among participants.The nut and olive oil diets induced a fatty acid composition that has been shown to be beneficial in the face of MetS. Therefore, a Mediterranean diet rich in fats of vegetable origin may be a useful tool for the management of MetS without the need for concerns over weight gain due to its high fat content.Controlled-Trials.com ISRCTN35739639.

Áreas temáticas: Zootecnia / recursos pesqueiros; Sociology; Sociología; Serviço social; Saúde coletiva; Química; Psychology; Psicología; Planejamento urbano e regional / demografia; Odontología; Nutrição; Multidisciplinary sciences; Multidisciplinary; Medicine (miscellaneous); Medicina veterinaria; Medicina iii; Medicina ii; Medicina i; Materiais; Matemática / probabilidade e estatística; Linguística e literatura; Letras / linguística; Interdisciplinary research in the social sciences; Interdisciplinar; Human geography and urban studies; History & philosophy of science; Historia; Geografía; Geociências; General medicine; General biochemistry,genetics and molecular biology; General agricultural and biological sciences; Farmacia; Environmental studies; Ensino; Engenharias iv; Engenharias iii; Engenharias ii; Engenharias i; Enfermagem; Educação física; Educação; Economia; Direito; Demography; Comunicação e informação; Ciências sociais aplicadas i; Ciências biológicas iii; Ciências biológicas ii; Ciências biológicas i; Ciências ambientais; Ciências agrárias i; Ciência política e relações internacionais; Ciência de alimentos; Ciência da computação; Biotecnología; Biology; Biodiversidade; Biochemistry, genetics and molecular biology (miscellaneous); Astronomia / física; Arquitetura, urbanismo e design; Archaeology; Antropologia / arqueologia; Anthropology; Agricultural and biological sciences (miscellaneous); Administração, ciências contábeis e turismo; Administração pública e de empresas, ciências contábeis e turismo

Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 19326203

Direcció de correo del autor: andres.diaz@urv.cat; monica.bullo@urv.cat; jordi.salas@urv.cat

Fecha de alta del registro: 2025-02-19

Versión del articulo depositado: info:eu-repo/semantics/publishedVersion

Enlace a la fuente original: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0085202

URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/

Referencia al articulo segun fuente origial: Plos One. 9 (3): e85202-e85202

Referencia de l'ítem segons les normes APA: Mayneris-Perxachs, Jordi; Sala-Vila, Aleix; Chisaguano, Maribel; Castellote, Ana I; Estruch, Ramon; Isabel Covas, Maria; Fito, Montserrat; Salas-Salva (2014). Effects of 1-year intervention with a mediterranean diet on plasma Fatty Acid composition and metabolic syndrome in a population at high cardiovascular risk. Plos One, 9(3), e85202-e85202. DOI: 10.1371/journal.pone.0085202

DOI del artículo: 10.1371/journal.pone.0085202

Entidad: Universitat Rovira i Virgili

Año de publicación de la revista: 2014

Tipo de publicación: Journal Publications