Autor según el artículo: Dasilva G; Pazos M; García-Egido E; Pérez-Jiménez J; Torres J; Giralt M; Nogués M; Medina I

Departamento: Ciències Mèdiques Bàsiques

Autor/es de la URV: Giralt Batista, Montserrat / Nogués Llort, Maria Rosa

Palabras clave: Shrob Oxidative stress Metabolism Metabolic syndrome Lipid mediators Inflammation Fatty acids Epa Dha Biomarkers oxidative stress metabolic syndrome lipid mediators inflammation epa dha

Resumen: © 2016 Elsevier Ltd. All rights reserved. The role of specific proportions of ω-3 EPA and DHA, in the modulation of inflammation and oxidative stress markers associated to the progression of Metabolic Syndrome was investigated. Potential inflammatory eicosanoids and docosanoids were discussed together to biomarkers of CVD, obesity, inflammation and oxidative stress in an animal model of metabolic disorders. Results evidenced a noteworthy health effect of 1:1 and 2:1 EPA:DHA proportions over 1:2 EPA:DHA based diets through a down-regulation in the production of strong pro-inflammatory ω-6 eicosanoids, a decrement of biomarkers of oxidative stress, and a modulation of fatty acid desaturase activities and plasma and membrane PUFAs towards greater anti-inflammatory profiles. Outcomes contribute to the general knowledge on the health benefits of marine lipids and their role on the progress of MetS, inflammation and oxidative stress. Results shed light on controversial protective mechanisms of EPA and DHA to better design dietary interventions aimed at reducing MetS.

Grupo de investigación: Farmacobiologia Cel.lular

Áreas temáticas: Zootecnia / recursos pesqueiros Saúde coletiva Química Odontología Nutrition & dietetics Nutrição Medicine (miscellaneous) Medicina veterinaria Medicina ii Medicina i Materiais Matemática / probabilidade e estatística Interdisciplinar Geociências Food science & technology Food science Farmacia Ensino Engenharias iv Engenharias iii Engenharias ii Engenharias i Enfermagem Educação física Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Chemistry, applied Biotecnología Biodiversidade Astronomia / física Analytical chemistry Administração pública e de empresas, ciências contábeis e turismo

Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 03088146

Direcció de correo del autor: mariarosa.nogues@urv.cat montse.giralt@urv.cat

Identificador del autor: 0000-0003-4626-5672 0000-0002-7073-577X

Fecha de alta del registro: 2023-02-19

Versión del articulo depositado: info:eu-repo/semantics/submittedVersion

Enlace a la fuente original: https://www.sciencedirect.com/science/article/abs/pii/S0308814616303715?via%3Dihub

URL Documento de licencia: http://repositori.urv.cat/ca/proteccio-de-dades/

Referencia al articulo segun fuente origial: Food Chemistry. 205 196-203

Referencia de l'ítem segons les normes APA: Dasilva G; Pazos M; García-Egido E; Pérez-Jiménez J; Torres J; Giralt M; Nogués M; Medina I (2016). Lipidomics to analyze the influence of diets with different EPA:DHA ratios in the progression of Metabolic Syndrome using SHROB rats as a model. Food Chemistry, 205(), 196-203. DOI: 10.1016/j.foodchem.2016.03.020

DOI del artículo: 10.1016/j.foodchem.2016.03.020

Entidad: Universitat Rovira i Virgili

Año de publicación de la revista: 2016

Tipo de publicación: Journal Publications