Autor según el artículo: Dasilva G; Pazos M; García-Egido E; Pérez-Jiménez J; Torres J; Giralt M; Nogués M; Medina I
Departamento: Ciències Mèdiques Bàsiques
Autor/es de la URV: Giralt Batista, Montserrat / Nogués Llort, Maria Rosa
Palabras clave: dha epa inflammation lipid mediators metabolic syndrome oxidative stress Biomarkers Dha Epa Fatty acids Inflammation Lipid mediators Metabolic syndrome Metabolism Oxidative stress Shrob
Resumen: © 2016 Elsevier Ltd. All rights reserved. The role of specific proportions of ω-3 EPA and DHA, in the modulation of inflammation and oxidative stress markers associated to the progression of Metabolic Syndrome was investigated. Potential inflammatory eicosanoids and docosanoids were discussed together to biomarkers of CVD, obesity, inflammation and oxidative stress in an animal model of metabolic disorders. Results evidenced a noteworthy health effect of 1:1 and 2:1 EPA:DHA proportions over 1:2 EPA:DHA based diets through a down-regulation in the production of strong pro-inflammatory ω-6 eicosanoids, a decrement of biomarkers of oxidative stress, and a modulation of fatty acid desaturase activities and plasma and membrane PUFAs towards greater anti-inflammatory profiles. Outcomes contribute to the general knowledge on the health benefits of marine lipids and their role on the progress of MetS, inflammation and oxidative stress. Results shed light on controversial protective mechanisms of EPA and DHA to better design dietary interventions aimed at reducing MetS.
Grupo de investigación: Farmacobiologia Cel.lular
Áreas temáticas: Administração pública e de empresas, ciências contábeis e turismo Analytical chemistry Astronomia / física Biodiversidade Biotecnología Chemistry, applied Ciência da computação Ciência de alimentos Ciências agrárias i Ciências ambientais Ciências biológicas i Ciências biológicas ii Ciências biológicas iii Educação física Enfermagem Engenharias i Engenharias ii Engenharias iii Engenharias iv Ensino Farmacia Food science Food science & technology Geociências Interdisciplinar Matemática / probabilidade e estatística Materiais Medicina i Medicina ii Medicina veterinaria Medicine (miscellaneous) Nutrição Nutrition & dietetics Odontología Química Saúde coletiva Zootecnia / recursos pesqueiros
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: montse.giralt@urv.cat mariarosa.nogues@urv.cat
ISSN: 03088146
Identificador del autor: 0000-0002-7073-577X 0000-0003-4626-5672
Fecha de alta del registro: 2023-02-19
Versión del articulo depositado: info:eu-repo/semantics/acceptedVersion
Enlace a la fuente original: https://www.sciencedirect.com/science/article/abs/pii/S0308814616303715?via%3Dihub
Referencia al articulo segun fuente origial: Food Chemistry. 205 196-203
Referencia de l'ítem segons les normes APA: Dasilva G; Pazos M; García-Egido E; Pérez-Jiménez J; Torres J; Giralt M; Nogués M; Medina I (2016). Lipidomics to analyze the influence of diets with different EPA:DHA ratios in the progression of Metabolic Syndrome using SHROB rats as a model. Food Chemistry, 205(), 196-203. DOI: 10.1016/j.foodchem.2016.03.020
URL Documento de licencia: http://repositori.urv.cat/ca/proteccio-de-dades/
DOI del artículo: 10.1016/j.foodchem.2016.03.020
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2016
Tipo de publicación: Journal Publications
Repositori URV