Autor según el artículo: Margalef R; Bosque M; Monclús P; Flores P; Minaya-Muñoz F; Valera-Garrido F; Santafé MM

Departamento: Ciències Mèdiques Bàsiques

Autor/es de la URV: Santafé Martínez, Manuel

Palabras clave: Twitch response Stimulation Potentials Pain Muscle Electrotaxis Common

Resumen: © 2020 R. Margalef et al. An increase in the spontaneous release of acetylcholine (ACh) at the motor endplate is directly related to the generation of myofascial trigger points (MTrPs). In this study, percutaneous electric fields were applied to an animal model of MTrPs with high levels of spontaneous ACh release. All experiments were performed on Swiss mice and Sprague Dawley rats. For evaluating the spontaneous neurotransmission, intracellular recordings were performed, and the frequency of miniature endplate potentials was evaluated. Electromyographic recordings were also conducted to evaluate the endplate noise. Finally, the number and strength of local twitch responses (LTR) were evaluated using ultrasound recordings. The protocols used for the electric currents were 0.4 mA for five seconds and four repetitions (protocol 1), 1.5 mA for five seconds and three repetitions (protocol 2), and 3 mA for three seconds and three repetitions (protocol 3). After a subcutaneous injection of neostigmine (NTG), a great increase was observed in the frequency of mEPPs, together with an elevated endplate noise. Protocols 2 and 3 were the most effective. Protocol 3 could completely reverse the action of NTG at both three hours and 24 hours, respectively. The application of percutaneous currents produced both an increase in the number (144%) and in the speed (230% faster) of LTR compared with dry needling. In conclusion, higher doses of electrical current are more effective for decreasing MTrPs findings in an animal model.

Áreas temáticas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Odontología Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Integrative & complementary medicine Farmacia Ensino Engenharias iv Engenharias ii Engenharias i Enfermagem Educação física Economia Complementary and alternative medicine Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Biotecnología Biodiversidade Astronomia / física Administração, ciências contábeis e turismo

Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/

Direcció de correo del autor: manuel.santafe@urv.cat

Identificador del autor: 0000-0002-5462-5108

Fecha de alta del registro: 2023-02-19

Versión del articulo depositado: info:eu-repo/semantics/publishedVersion

Enlace a la fuente original: https://www.hindawi.com/journals/ecam/2020/4173218/

URL Documento de licencia: http://repositori.urv.cat/ca/proteccio-de-dades/

Referencia al articulo segun fuente origial: Evidence-Based Complementary And Alternative Medicine. 2020 (4173218): 4173218-

Referencia de l'ítem segons les normes APA: Margalef R; Bosque M; Monclús P; Flores P; Minaya-Muñoz F; Valera-Garrido F; Santafé MM (2020). Percutaneous Application of Galvanic Current in Rodents Reverses Signs of Myofascial Trigger Points. Evidence-Based Complementary And Alternative Medicine, 2020(4173218), 4173218-. DOI: 10.1155/2020/4173218

DOI del artículo: 10.1155/2020/4173218

Entidad: Universitat Rovira i Virgili

Año de publicación de la revista: 2020

Tipo de publicación: Journal Publications