Autor según el artículo: Gaudet A; Martin-Loeches I; Povoa P; Rodriguez A; Salluh J; Duhamel A; Nseir S
Departamento: Medicina i Cirurgia
Autor/es de la URV: Rodríguez Oviedo, Alejandro Hugo
Palabras clave: Tracheobronchitis Pneumonia Mechanical ventilation Lower respiratory tract infection Intensive-care-unit Diagnosis Cpis
Resumen: © 2020, The Author(s). Background: Differentiating Ventilator-Associated Tracheobronchitis (VAT) from Ventilator-Associated Pneumonia (VAP) may be challenging for clinicians, yet their management currently differs. In this study, we evaluated the accuracy of the Clinical Pulmonary Infection Score (CPIS) to differentiate VAT and VAP. Methods: We performed a retrospective analysis based on the data from 2 independent prospective cohorts. Patients of the TAVeM database with a diagnosis of VAT (n = 320) or VAP (n = 369) were included in the derivation cohort. Patients admitted to the Intensive Care Centre of Lille University Hospital between January 1, 2016 and December 31, 2017 who had a diagnosis of VAT (n = 70) or VAP (n = 139) were included in the validation cohort. The accuracy of the CPIS to differentiate VAT from VAP was assessed within the 2 cohorts by calculating sensitivity and specificity values, establishing the ROC curves and choosing the best threshold according to the Youden index. Results: The areas under ROC curves of CPIS to differentiate VAT from VAP were calculated at 0.76 (95% CI [0.72–0.79]) in the derivation cohort and 0.67 (95% CI [0.6–0.75]) in the validation cohort. A CPIS value ≥ 7 was associated with the highest Youden index in both cohorts. With this cut-off, sensitivity and specificity were respectively found at 0.51 and 0.88 in the derivation cohort, and at 0.45 and 0.89 in the validation cohort. Conclusions: A CPIS value ≥ 7 reproducibly allowed to differentiate VAT from VAP with high specificity and PPV and moderate sensitivity and NPV in our derivation and validation cohorts.
Áreas temáticas: Saúde coletiva Medicina iii Medicina ii Medicina i Engenharias iv Critical care medicine Critical care and intensive care medicine Ciências biológicas ii
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: alejandrohugo.rodriguez@urv.cat
Identificador del autor: 0000-0001-8828-5984
Fecha de alta del registro: 2023-09-02
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://annalsofintensivecare.springeropen.com/articles/10.1186/s13613-020-00721-4
URL Documento de licencia: http://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Annals Of Intensive Care. 10 (1): 101-
Referencia de l'ítem segons les normes APA: Gaudet A; Martin-Loeches I; Povoa P; Rodriguez A; Salluh J; Duhamel A; Nseir S (2020). Accuracy of the clinical pulmonary infection score to differentiate ventilator-associated tracheobronchitis from ventilator-associated pneumonia. Annals Of Intensive Care, 10(1), 101-. DOI: 10.1186/s13613-020-00721-4
DOI del artículo: 10.1186/s13613-020-00721-4
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2020
Tipo de publicación: Journal Publications
Repositori URV