Articles producció científica> Ciències Mèdiques Bàsiques

Effects of dietary phytoestrogens on hormones throughout a human lifespan: A review

  • Datos identificativos

    Identificador: imarina:7979889
    Autores:
    Domínguez-López IYago-Aragón MSalas-Huetos ATresserra-Rimbau AHurtado-Barroso S
    Resumen:
    © 2020 by the authors. Licensee MDPI, Basel, Switzerland. Dietary phytoestrogens are bioactive compounds with estrogenic activity. With the growing popularity of plant-based diets, the intake of phytoestrogen-rich legumes (especially soy) and legume-derived foods has increased. Evidence from preclinical studies suggests these compounds may have an effect on hormones and health, although the results of human trials are unclear. The effects of dietary phytoestrogens depend on the exposure (phytoestrogen type, matrix, concentration, and bioavailability), ethnicity, hormone levels (related to age, sex, and physiological condition), and health status of the consumer. In this review, we have summarized the results of human studies on dietary phytoestrogens with the aim of assessing the possible hormone-dependent outcomes and health effects of their consumption throughout a lifespan, focusing on pregnancy, childhood, adulthood, and the premenopausal and postmenopausal stages. In pregnant women, an improvement of insulin metabolism has been reported in only one study. Sex hormone alterations have been found in the late stages of childhood, and goitrogenic effects in children with hypothyroidism. In premenopausal and postmenopausal women, the reported impacts on hormones are inconsistent, although beneficial goitrogenic effects and improved glycemic control and cardiovascular risk markers have been described in postmenopausal individuals. In adult men, different authors report goitrogenic effects and a reduction of insulin in non-alcoholic fatty liver patients. Further carefully designed studies are warranted to better elucidate the impact of phytoestrogen consumption on the endocrine system at different life stages.
  • Otros:

    Autor según el artículo: Domínguez-López I; Yago-Aragón M; Salas-Huetos A; Tresserra-Rimbau A; Hurtado-Barroso S
    Departamento: Ciències Mèdiques Bàsiques
    Autor/es de la URV: Salas Huetos, Albert
    Palabras clave: Bone-mineral density Breast-cancer risk Cardiovascular risk-factors Dietary flavonoids Double-blind Endocrine Estrogenic Flaxseeds Growth-factor-i Health High-dose isoflavones Isoflavones Lignans Polyphenols Postmenopausal japanese women Sex-hormones Soy Soy protein isolate Stages of life Urinary estrogen metabolites
    Resumen: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. Dietary phytoestrogens are bioactive compounds with estrogenic activity. With the growing popularity of plant-based diets, the intake of phytoestrogen-rich legumes (especially soy) and legume-derived foods has increased. Evidence from preclinical studies suggests these compounds may have an effect on hormones and health, although the results of human trials are unclear. The effects of dietary phytoestrogens depend on the exposure (phytoestrogen type, matrix, concentration, and bioavailability), ethnicity, hormone levels (related to age, sex, and physiological condition), and health status of the consumer. In this review, we have summarized the results of human studies on dietary phytoestrogens with the aim of assessing the possible hormone-dependent outcomes and health effects of their consumption throughout a lifespan, focusing on pregnancy, childhood, adulthood, and the premenopausal and postmenopausal stages. In pregnant women, an improvement of insulin metabolism has been reported in only one study. Sex hormone alterations have been found in the late stages of childhood, and goitrogenic effects in children with hypothyroidism. In premenopausal and postmenopausal women, the reported impacts on hormones are inconsistent, although beneficial goitrogenic effects and improved glycemic control and cardiovascular risk markers have been described in postmenopausal individuals. In adult men, different authors report goitrogenic effects and a reduction of insulin in non-alcoholic fatty liver patients. Further carefully designed studies are warranted to better elucidate the impact of phytoestrogen consumption on the endocrine system at different life stages.
    Áreas temáticas: Biotecnología Ciência de alimentos Ciências agrárias i Ciências biológicas i Ciências biológicas ii Ciências biológicas iii Economia Educação física Enfermagem Engenharias ii Engenharias iv Farmacia Food science Interdisciplinar Medicina i Medicina ii Medicina iii Medicina veterinaria Nutrição Nutrition & dietetics Nutrition and dietetics Planejamento urbano e regional / demografia Psicología Química Saúde coletiva Zootecnia / recursos pesqueiros
    Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
    Direcció de correo del autor: albert.salas@urv.cat
    Identificador del autor: 0000-0001-5914-6862
    Fecha de alta del registro: 2022-10-30
    Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
    Referencia al articulo segun fuente origial: Nutrients. 12 (8): 1-25
    Referencia de l'ítem segons les normes APA: Domínguez-López I; Yago-Aragón M; Salas-Huetos A; Tresserra-Rimbau A; Hurtado-Barroso S (2020). Effects of dietary phytoestrogens on hormones throughout a human lifespan: A review. Nutrients, 12(8), 1-25. DOI: 10.3390/nu12082456
    URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
    Entidad: Universitat Rovira i Virgili
    Año de publicación de la revista: 2020
    Tipo de publicación: Journal Publications
  • Palabras clave:

    Food Science,Nutrition & Dietetics,Nutrition and Dietetics
    Bone-mineral density
    Breast-cancer risk
    Cardiovascular risk-factors
    Dietary flavonoids
    Double-blind
    Endocrine
    Estrogenic
    Flaxseeds
    Growth-factor-i
    Health
    High-dose isoflavones
    Isoflavones
    Lignans
    Polyphenols
    Postmenopausal japanese women
    Sex-hormones
    Soy
    Soy protein isolate
    Stages of life
    Urinary estrogen metabolites
    Biotecnología
    Ciência de alimentos
    Ciências agrárias i
    Ciências biológicas i
    Ciências biológicas ii
    Ciências biológicas iii
    Economia
    Educação física
    Enfermagem
    Engenharias ii
    Engenharias iv
    Farmacia
    Food science
    Interdisciplinar
    Medicina i
    Medicina ii
    Medicina iii
    Medicina veterinaria
    Nutrição
    Nutrition & dietetics
    Nutrition and dietetics
    Planejamento urbano e regional / demografia
    Psicología
    Química
    Saúde coletiva
    Zootecnia / recursos pesqueiros
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