Autor según el artículo: Dominguez-Lopez, Ines; Yago-Aragon, Maria; Salas-Huetos, Albert; Tresserra-Rimbau, Anna; Hurtado-Barroso, Sara
Departamento: Ciències Mèdiques Bàsiques
Autor/es de la URV: Salas Huetos, Albert
Palabras clave: Vegetables Urinary estrogen metabolites Stages of life Soy protein isolate Soy Sex-hormones Premenopause Pregnancy Postmenopause Postmenopausal japanese women Polyphenols Phytoestrogens Non-alcoholic fatty liver disease Male Longevity Lignans Isoflavones Hypothyroidism Humans Hormones High-dose isoflavones Heart disease risk factors Health Growth-factor-i Gonadal steroid hormones Glycine max Flaxseeds Female Estrogenic Endocrine Double-blind Dietary flavonoids Diet Child Cardiovascular risk-factors Breast-cancer risk Bone-mineral density Adult
Resumen: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. Dietary phytoestrogens are bioactive compounds with estrogenic activity. With the growing popularity of plant-based diets, the intake of phytoestrogen-rich legumes (especially soy) and legume-derived foods has increased. Evidence from preclinical studies suggests these compounds may have an effect on hormones and health, although the results of human trials are unclear. The effects of dietary phytoestrogens depend on the exposure (phytoestrogen type, matrix, concentration, and bioavailability), ethnicity, hormone levels (related to age, sex, and physiological condition), and health status of the consumer. In this review, we have summarized the results of human studies on dietary phytoestrogens with the aim of assessing the possible hormone-dependent outcomes and health effects of their consumption throughout a lifespan, focusing on pregnancy, childhood, adulthood, and the premenopausal and postmenopausal stages. In pregnant women, an improvement of insulin metabolism has been reported in only one study. Sex hormone alterations have been found in the late stages of childhood, and goitrogenic effects in children with hypothyroidism. In premenopausal and postmenopausal women, the reported impacts on hormones are inconsistent, although beneficial goitrogenic effects and improved glycemic control and cardiovascular risk markers have been described in postmenopausal individuals. In adult men, different authors report goitrogenic effects and a reduction of insulin in non-alcoholic fatty liver patients. Further carefully designed studies are warranted to better elucidate the impact of phytoestrogen consumption on the endocrine system at different life stages.
Áreas temáticas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: albert.salas@urv.cat
Identificador del autor: 0000-0001-5914-6862
Fecha de alta del registro: 2025-02-18
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Nutrients. 12 (8): 1-25
Referencia de l'ítem segons les normes APA: Dominguez-Lopez, Ines; Yago-Aragon, Maria; Salas-Huetos, Albert; Tresserra-Rimbau, Anna; Hurtado-Barroso, Sara (2020). Effects of dietary phytoestrogens on hormones throughout a human lifespan: A review. Nutrients, 12(8), 1-25. DOI: 10.3390/nu12082456
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2020
Tipo de publicación: Journal Publications