Autor según el artículo: Diaz-Lopez, Andres; Paz-Graniel, Indira; Ruiz, Veronica; Toledo, Estefania; Becerra-Tomas, Nerea; Corella, Dolores; Castaner, Olga; Martinez, J. Alfredo; Alonso-Gomez, Angel M.; Warnberg, Julia; Vioque, Jesus; Romaguera, Dora; Lopez-Miranda, Jose; Estruch, Ramon; Tinahones, Francisco J.; Lapetra, Jose; Serra-Majem, Luis; Bueno-Cavanillas, Aurora; Tur, Josep A.; Sanchez, Vicente Martin; Pinto, Xavier; Delgado-Rodriguez, Miguel; Matia-Martin, Pilar; Vidal, Josep; Vazquez, Clotilde; Daimiel, Lidia; Villa, Tania Fernandez; Ros, Emilio; Eguaras, Sonia; Babio, Nancy; Sorli, Jose V.; Goday, Albert; Abete, Itziar; Sierra, Lucas Tojal; Baron-Lopez, Francisco Javier; Torres-Collado, Laura; Morey, Marga; Garcia-Rios, Antonio; Casas, Rosa; Bernal-Lopez, Maria Rosa; Santos-Lozano, Jose Manuel; Navarro, Adela; Gonzalez, Jose I.; Zomeno, Maria Dolores; Zulet, Maria Angeles; Luna, Jessica Vaquero; Ramallal, Raul; Fito, Montse; Salas-Salvado, Jordi;

Departamento: Ciències Mèdiques Bàsiques Bioquímica i Biotecnologia

Autor/es de la URV: Babio Sánchez, Nancy Elvira / Becerra Tomás, Nerea / Díaz López, Andres / Paz Graniel, Indira del Socorro / Salas Salvadó, Jorge

Palabras clave: Tea Spain Risk Questionnaire Pathophysiology Outcomes Middle aged Metabolic syndrome x Metabolic syndrome Male Kidney Hyperfiltration Humans Human Health Glomerulus filtration rate Glomerular-filtration-rate Glomerular filtration rate Female Drinking behavior Cohort studies Cohort analysis Coffee consumption Coffee Cardiovascular-diseases Caffeine Association Aged

Resumen: It remains unclear whether caffeinated beverages could have deleterious renal effects in elderly population with underlying comorbid conditions. We investigated the associations between coffee, tea, or caffeine intake and 1-year changes in glomerular filtration rate (eGFR) in a large Spanish cohort of overweight/obese elderly with metabolic syndrome (MetS). This prospective analysis includes 5851 overweight/obese adults (55-75 years) with MetS from the PREDIMED-Plus study. We assessed coffee, tea, and caffeine consumption from a validated food-frequency questionnaire and creatinine-based eGFR using the Chronic Kidney Disease Epidemiology Collaboration equation. Multivariate-adjusted regression models were applied to test associations between baseline coffee, tea, or caffeine intake and 1-year eGFR changes. Caffeinated coffee (> 2 cups/day) and tea (at least 1 cup/day) drinkers had 0.88 and 0.93 mL/min/1.73 m(2) greater eGFR decrease respectively, compared to those with less than 1 cup/day of coffee consumption or non-tea drinkers. Furthermore, caffeinated coffee consumption of > 2 cups/day was associated with 1.19-fold increased risk of rapid eGFR decline > 3 mL/min/1.73 m(2) (95% CI 1.01-1.41). Similarly, individuals in the highest (median, 51.2 mg/day) tertile of caffeine intake had a 0.87 mL/min/1.73 m(2) greater eGFR decrease. Decaffeinated coffee was not associated with eGFR changes. In conclusion, higher consumption of caffeinated coffee, tea, and caffeine was associated with a greater 1-year eGFR decline in overweight/obese adults with MetS.

Áreas temáticas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Odontología Nutrição Multidisciplinary sciences Multidisciplinary Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Matemática / probabilidade e estatística Letras / linguística Interdisciplinar Geografía Geociências Farmacia Engenharias iv Engenharias iii Engenharias ii Enfermagem Educação física Educação Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Biotecnología Biodiversidade Astronomia / física

Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/

Direcció de correo del autor: indiradelsocorro.paz@urv.cat nerea.becerra@urv.cat andres.diaz@urv.cat nancy.babio@urv.cat jordi.salas@urv.cat indiradelsocorro.paz@urv.cat

Identificador del autor: 0000-0002-4429-6507 0000-0002-7500-5629 0000-0003-3527-5277 0000-0003-2700-7459

Fecha de alta del registro: 2023-02-19

Versión del articulo depositado: info:eu-repo/semantics/publishedVersion

Enlace a la fuente original: https://www.nature.com/articles/s41598-021-88028-7

URL Documento de licencia: http://repositori.urv.cat/ca/proteccio-de-dades/

Referencia al articulo segun fuente origial: Scientific Reports. 11 (1):

Referencia de l'ítem segons les normes APA: Diaz-Lopez, Andres; Paz-Graniel, Indira; Ruiz, Veronica; Toledo, Estefania; Becerra-Tomas, Nerea; Corella, Dolores; Castaner, Olga; Martinez, J. Alfre (2021). Consumption of caffeinated beverages and kidney function decline in an elderly Mediterranean population with metabolic syndrome. Scientific Reports, 11(1), -. DOI: 10.1038/s41598-021-88028-7

DOI del artículo: 10.1038/s41598-021-88028-7

Entidad: Universitat Rovira i Virgili

Año de publicación de la revista: 2021

Tipo de publicación: Journal Publications