Articles producció científica> Medicina i Cirurgia

Gut microbiota profile and its association with clinical variables and dietary intake in overweight/obese and lean subjects: A cross-sectional study

  • Datos identificativos

    Identificador: imarina:9218785
    Autores:
    Companys, JuditGosalbes, Maria JosePla-Paga, LauraCalderon-Perez, LorenaLlaurado, ElisabetPedret, AnnaValls, Rosa MariaJimenez-Hernandez, NuriaSandoval-Ramirez, Berner Andreedel Bas, Josep MariaCaimari, AntoniRubio, LauraSola, Rosa
    Resumen:
    We aimed to differentiate gut microbiota composition of overweight/obese and lean subjects and to determine its association with clinical variables and dietary intake. A cross-sectional study was performed with 96 overweight/obese subjects and 32 lean subjects. Anthropometric parameters were positively associated with Collinsella aerofaciens, Dorea formicigenerans and Dorea longicatena, which had higher abundance the overweight/obese subjects. Moreover, different genera of Lachnospiraceae were negatively associated with body fat, LDL and total cholesterol. Saturated fatty acids (SFAs) were negatively associated with the genus Intestinimonas, a biomarker of the overweight/obese group, whereas SFAs were positively associated with Roseburia, a biomarker for the lean group. In conclusion, Dorea formicigenerans, Dorea longicatena and Collinsella aerofaciens could be considered obesity biomarkers, Lachnospiraceae is associated with lipid cardiovascular risk factors. SFAs exhibited opposite association profiles with butyrate-producing bacteria depending on the BMI. Thus, the relationship between diet and microbiota opens new tools for the management of obesity.
  • Otros:

    Autor según el artículo: Companys, Judit; Gosalbes, Maria Jose; Pla-Paga, Laura; Calderon-Perez, Lorena; Llaurado, Elisabet; Pedret, Anna; Valls, Rosa Maria; Jimenez-Hernandez, Nuria; Sandoval-Ramirez, Berner Andree; del Bas, Josep Maria; Caimari, Antoni; Rubio, Laura; Sola, Rosa
    Departamento: Medicina i Cirurgia
    Autor/es de la URV: Calderon Pérez, Lorena / Companys Alemany, Judit / Llauradó Ribé, Elisabet / Pedret Figuerola, Anna / PLA PAGA, LAURA / SANDOVAL RAMÍREZ, BERNER ANDRÉE / Solà Alberich, Rosa Maria / Valls Zamora, Rosa Maria
    Palabras clave: Thinness Saturated fatty acids Potassium Overweight Obesity Middle aged Male Humans Gut microbiota Gastrointestinal microbiome Female Feces Energy intake Eating Dietary intake Dietary fats Dietary carbohydrates Diet Cross-sectional studies Clostridiales Body mass index Bacteria Adult Actinobacteria weight saturated fatty acids population gut microbiota dietary intake alignment
    Resumen: We aimed to differentiate gut microbiota composition of overweight/obese and lean subjects and to determine its association with clinical variables and dietary intake. A cross-sectional study was performed with 96 overweight/obese subjects and 32 lean subjects. Anthropometric parameters were positively associated with Collinsella aerofaciens, Dorea formicigenerans and Dorea longicatena, which had higher abundance the overweight/obese subjects. Moreover, different genera of Lachnospiraceae were negatively associated with body fat, LDL and total cholesterol. Saturated fatty acids (SFAs) were negatively associated with the genus Intestinimonas, a biomarker of the overweight/obese group, whereas SFAs were positively associated with Roseburia, a biomarker for the lean group. In conclusion, Dorea formicigenerans, Dorea longicatena and Collinsella aerofaciens could be considered obesity biomarkers, Lachnospiraceae is associated with lipid cardiovascular risk factors. SFAs exhibited opposite association profiles with butyrate-producing bacteria depending on the BMI. Thus, the relationship between diet and microbiota opens new tools for the management of obesity.
    Áreas temáticas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología
    Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
    Direcció de correo del autor: judit.companys@urv.cat lorena.calderon@urv.cat anna.pedret@urv.cat elisabet.llaurado@urv.cat judit.companys@urv.cat judit.companys@urv.cat lorena.calderon@urv.cat rosamaria.valls@urv.cat rosa.sola@urv.cat
    Identificador del autor: 0000-0003-1485-0818 0000-0003-0766-0733 0000-0002-5327-932X 0000-0002-7439-9531 0000-0003-1485-0818 0000-0003-1485-0818 0000-0003-0766-0733 0000-0002-3351-0942 0000-0002-8359-235X
    Fecha de alta del registro: 2024-10-19
    Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
    Enlace a la fuente original: https://www.mdpi.com/2072-6643/13/6/2032
    URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referencia al articulo segun fuente origial: Nutrients. 13 (6): 2032-
    Referencia de l'ítem segons les normes APA: Companys, Judit; Gosalbes, Maria Jose; Pla-Paga, Laura; Calderon-Perez, Lorena; Llaurado, Elisabet; Pedret, Anna; Valls, Rosa Maria; Jimenez-Hernandez (2021). Gut microbiota profile and its association with clinical variables and dietary intake in overweight/obese and lean subjects: A cross-sectional study. Nutrients, 13(6), 2032-. DOI: 10.3390/nu13062032
    DOI del artículo: 10.3390/nu13062032
    Entidad: Universitat Rovira i Virgili
    Año de publicación de la revista: 2021
    Tipo de publicación: Journal Publications
  • Palabras clave:

    Food Science,Nutrition & Dietetics,Nutrition and Dietetics
    Thinness
    Saturated fatty acids
    Potassium
    Overweight
    Obesity
    Middle aged
    Male
    Humans
    Gut microbiota
    Gastrointestinal microbiome
    Female
    Feces
    Energy intake
    Eating
    Dietary intake
    Dietary fats
    Dietary carbohydrates
    Diet
    Cross-sectional studies
    Clostridiales
    Body mass index
    Bacteria
    Adult
    Actinobacteria
    weight
    saturated fatty acids
    population
    gut microbiota
    dietary intake
    alignment
    Zootecnia / recursos pesqueiros
    Saúde coletiva
    Química
    Psicología
    Planejamento urbano e regional / demografia
    Nutrition and dietetics
    Nutrition & dietetics
    Nutrição
    Medicina veterinaria
    Medicina iii
    Medicina ii
    Medicina i
    Interdisciplinar
    Food science
    Farmacia
    Engenharias iv
    Engenharias ii
    Enfermagem
    Educação física
    Economia
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências agrárias i
    Ciência de alimentos
    Biotecnología
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