Autor según el artículo: Alexandra Iakab, Stefania; Rafols, Pere; Garcia-Altares, Maria; Yanes, Oscar; Correig, Xavier
Departamento: Enginyeria Electrònica, Elèctrica i Automàtica
Autor/es de la URV: Correig Blanchar, Francesc Xavier / Garcia-Altares Pérez, Maria / Ràfols Soler, Pere / Yanes Torrado, Óscar
Palabras clave: Surface functionalization Silver nanoparticles Silicon nanostructures Selective enrichment Nanowire arrays Nanostructure Ms analysis Modified porous silicon Mass spectrometry imaging (msi) Maldi Laser desorption ionization (ldi) Ion formation High-sensitivity Desorption/ionization
Resumen: Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is widely used in the biomedical field for the label-free analysis of molecules such as drugs, lipids, peptides, proteins, and biological tissues for molecular imaging. However, organic matrices used in traditional MALDI-MS applications introduce excessive interferences in the low m/z range. For this reason, nanostructured materials-and in particular silicon-based LDI strategies-have become a promising alternative, since they provide a much weaker background. Herein, the recent developments in fabrication, functionalization, and practical applications of silicon-based LDI-MS methods are reviewed. Also the basic requirements of silicon-based substrates for optimal LDI analysis by providing an overview of the LDI mechanisms that use silicon-based substrates instead of organic matrices are reported. Finally, the considerable potential of silicon-based substrates is discussed, giving suggestions for topics for future research.
Áreas temáticas: Química Physics, condensed matter Physics, applied Nanoscience and nanotechnology Nanoscience & nanotechnology Materials science, multidisciplinary Materials science (miscellaneous) Materials science (all) Materiais General materials science General chemistry Engenharias iv Engenharias ii Electronic, optical and magnetic materials Electrochemistry Condensed matter physics Ciências agrárias i Chemistry, physical Chemistry, multidisciplinary Chemistry (miscellaneous) Chemistry (all) Biomaterials Astronomia / física
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: oscar.yanes@urv.cat maria.garcia-altares@urv.cat pere.rafols@urv.cat xavier.correig@urv.cat
Identificador del autor: 0000-0003-3695-7157 0000-0002-9240-4058 0000-0002-6902-3054
Fecha de alta del registro: 2024-10-12
Versión del articulo depositado: info:eu-repo/semantics/acceptedVersion
Enlace a la fuente original: https://onlinelibrary.wiley.com/doi/full/10.1002/adfm.201903609
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Advanced Functional Materials. 29 (45): 1903609-
Referencia de l'ítem segons les normes APA: Alexandra Iakab, Stefania; Rafols, Pere; Garcia-Altares, Maria; Yanes, Oscar; Correig, Xavier (2019). Silicon-Based Laser Desorption Ionization Mass Spectrometry for the Analysis of Biomolecules: A Progress Report. Advanced Functional Materials, 29(45), 1903609-. DOI: 10.1002/adfm.201903609
DOI del artículo: 10.1002/adfm.201903609
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2019
Tipo de publicación: Journal Publications
Repositori URV