Autor según el artículo: Pinar-Marti, Ariadna; Fernandez-Barres, Silvia; Gignac, Florence; Persavento, Cecilia; Delgado, Anna; Romaguera, Dora; Lazaro, Iolanda; Ros, Emilio; Lopez-Vicente, Monica; Salas-Salvado, Jordi; Sala-Vila, Aleix; Julvez, Jordi
Departamento: Bioquímica i Biotecnologia
Autor/es de la URV: Salas Salvadó, Jorge
Palabras clave: Polyunsaturated fatty acids; Omega-3; Docosahexaenoic acid (dha); Attention; Alpha-linolenic acid (ala); Adolescence
Resumen: Omega-3 fatty acids are critical for brain function. Adolescence is increasingly believed to entail brain vulnerability to dietary intake. In contrast to the abundant research on the omega-3 docosahexaenoic acid (DHA) in cognition, research on DHA and attention in healthy adolescents is scarce. In addition, the role of alpha-linolenic acid (ALA), the vegetable omega-3 fatty acid, is unexplored. We examined associations between DHA and ALA and attention function among a healthy young population. In this cross-sectional study conducted in 372 adolescents (13.8 ± 0.9 years-old), we determined the red blood cell proportions of DHA and ALA by gas chromatography (objective biomarkers of their long-term dietary intake) and measured attention scores through the Attention Network Test. We constructed multivariable linear regression models to analyze associations, controlling for known confounders. Compared to participants at the lowest DHA tertile (reference), those at the highest DHA tertile showed significantly lower hit reaction time-standard error (higher attentiveness) (28.13 ms, 95% confidence interval [CI] = – 52.30; – 3.97), lower hit reaction time (– 38.30 ms, 95% CI = – 73.28; – 3.33) and lower executive conflict response (– 5.77 ms, 95% CI = – 11.44; – 0.09). In contrast, higher values were observed in those at the top tertile of ALA in hit reaction time compared to the lowest one (46.14 ms, 95% CI = 9.90; 82.34). However, a beneficial association was observed for ALA, with decreasing impulsivity index across tertiles. Overall, our results suggest that DHA (reflecting its dietary intake) is associated with attention performance in typically developing adolescents. The role of dietary ALA in attention is less clear, although higher blood levels of ALA appear to result in lower impulsivity. Future intervention studies are needed to determine the causality of these associations and to better shape dietary recommendations for brain health during the adolescence period.
Áreas temáticas: Psychology, developmental; Psychology; Psychiatry and mental health; Psychiatry; Psicología; Philosophy; Pediatrics, perinatology and child health; Pediatrics; Medicine (miscellaneous); Medicina ii; Medicina i; Interdisciplinar; General medicine; Farmacia; Engenharias iv; Educação; Developmental and educational psychology; Ciencias sociales; Ciencias humanas; Ciências biológicas ii; Ciências biológicas i
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: jordi.salas@urv.cat
Fecha de alta del registro: 2025-02-18
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://link.springer.com/article/10.1007/s00787-022-02064-w
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: European Child & Adolescent Psychiatry. 32 (11): 2187-2195
Referencia de l'ítem segons les normes APA: Pinar-Marti, Ariadna; Fernandez-Barres, Silvia; Gignac, Florence; Persavento, Cecilia; Delgado, Anna; Romaguera, Dora; Lazaro, Iolanda; Ros, Emilio; L (2023). Red blood cell omega-3 fatty acids and attention scores in healthy adolescents. European Child & Adolescent Psychiatry, 32(11), 2187-2195. DOI: 10.1007/s00787-022-02064-w
DOI del artículo: 10.1007/s00787-022-02064-w
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2023
Tipo de publicación: Journal Publications
Repositori URV