Autor según el artículo: Iglesias-Vazquez, Lucia; Hernandez-Martinez, Carmen; Voltas, Nuria; Canals, Josefa; Coronel, Pilar; Gimeno, Mercedes; Arija, Victoria;
Departamento: Psicologia
Autor/es de la URV: Arija Val, Maria Victoria / Canals Sans, Josefa / Hernandez Martinez, Carmen / Iglesias Vazquez, Lucia / Voltas Moreso, Núria
Palabras clave: Risk Prophylaxis Prenatal Pregnancy Population Neurodevelopment Motor development Language development Iron supplementation Hfe gene Hemoglobin levels Deficiency Cognitive development Brain-development Anemia Age
Resumen: Background: Prenatal prescription of standard iron supplements to prevent iron deficiency appears not to be appropriate for all women and their children, as some women may be at risk of iron deficiency and others at risk of iron excess early in pregnancy. The present study aimed to assess whether prenatal iron supplementation adapted to the needs of each pregnant woman affects their child's neurodevelopment.Methods: Follow-up of a community-based RCT involving 503 mother-child pairs. Non-anaemic pregnant women recruited in Tarragona (Spain) early in pregnancy were prescribed a daily iron dose based on their initial haemoglobin levels: Stratum 1 (Hb =110-130 g/L, 80 or 40 mg/d of iron) and Stratum 2 (Hb >130 g/L, 40 or 20 mg/d of iron). Women receiving 40 mg/d were considered the control group in each Strata. The child's neurodevelopment was assessed at 40 days of age using the Bayley Scales of Infant Development-III (BSID-III). Adjusted multiple regression models were used.Results: Multiple regression analyses showed no association between the intervention and control group within each Strata on the BSID-III scores on any of the developmental scales in children, including cognitive, language, and motor development: Stratum 1 (beta 1.46, 95%CI -2.15, 5.07; beta 1.30, 95%CI -1.99, 4.59; and beta 2.04, 95%CI -3.88, 7.96, respectively) and Stratum 2 (beta -4.04, 95%CI -7.27, 0.80; beta -0.36, 95%CI -3.47, 2.75; and beta -3.76, 95%CI -9.30, 1.78, respectively).Conclusions: In non-anaemic women in early pregnancy, no differences were found in the cognitive, language and motor development of children at 40 days of age between the dose of iron tested in each case -adjusted to initial Hb levels- compared to the dose of the control group. Further studies are guaranteed to confirm our findings.
Áreas temáticas: Surgery Serviço social Saúde coletiva Odontología Obstetrics and gynecology Obstetrics & gynecology Nutrição Medicina iii Medicina ii Medicina i Materiais Matemática / probabilidade e estatística Interdisciplinar Ensino Enfermagem Educação física Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Biotecnología Administração pública e de empresas, ciências contábeis e turismo
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: nuria.voltas@urv.cat lucia.iglesias@urv.cat carmen.hernandez@urv.cat josefa.canals@urv.cat victoria.arija@urv.cat
Identificador del autor: 0000-0001-8855-0282 0000-0001-7131-4144 0000-0001-6328-8679 0000-0002-6209-9558 0000-0002-1758-0975
Fecha de alta del registro: 2024-09-07
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Bmc Pregnancy And Childbirth. 22 (1):
Referencia de l'ítem segons les normes APA: Iglesias-Vazquez, Lucia; Hernandez-Martinez, Carmen; Voltas, Nuria; Canals, Josefa; Coronel, Pilar; Gimeno, Mercedes; Arija, Victoria; (2022). Adapting prenatal iron supplementation to maternal needs results in optimal child neurodevelopment: a follow-up of the ECLIPSES Study. Bmc Pregnancy And Childbirth, 22(1), -. DOI: 10.1186/s12884-022-05033-y
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2022
Tipo de publicación: Journal Publications
Repositori URV