Autor según el artículo: Espinel, E; Azancot, MA; Gomez, A; Beneria, A; Caraben, A; Andurell, L; Delgado, P; Castane, H; Joven, J; Seron, D
Departamento: Medicina i Cirurgia
Autor/es de la URV: Castañé Vilafranca, Helena / Joven Maried, Jorge
Palabras clave: Weight-loss Weight management Therapy Therapeutics Surge Prevalence Patterns Metaanalysis Management Hypertension Denervation Clinical-relevance Adults
Resumen: Hypertension is a common chronic medical condition. Treatment is not satisfactory in a significant proportion of patients with primary hypertension, despite the concurrent use of three or more medications with different mechanisms of action. Such treatment-resistant hypertension is a clinical challenge associated with poor prognosis and needs further investigation. The efficacy of lifestyle changes has not been established yet in patients with resistant hypertension, and educational efforts appear clinically irrelevant in patients who must achieve behavioral changes without supervision. A 6-month multidisciplinary pilot intervention enrolled 50 patients with established resistant hypertension. The aims were: (1) to examine whether intensive and supervised lifestyle changes contribute to decreasing blood pressure in this condition, and (2) to identify which components affect compliance and feasibility. The program provided intensive changes in nutrition, physical exercise, and control of sleep disturbances supervised by nutritionists, physiotherapists, and psychologists. Nurses and pharmacists followed up on adherence to the antihypertensive medication. The primary outcome was 24 h blood pressure control. Data in patients with full compliance (n = 30) indicate that lifestyle modifications in resistant hypertension significantly reduced 24 h both systolic and diastolic blood pressure (p < 0.01), body mass index (p < 0.01), medication burden (p = 0.04), improving physical fitness, and cardiovascular risk markers such as heart rate (p = 0.01) and augmentation index (p = 0.02). The adherence to the intervention was moderate, with an attrition rate of 12%. A modified version reducing visits and explorations will likely improve compliance and can be used to assess the long-term maintenance of these benefits in managing resistant hypertension by diverse healthcare providers.
Áreas temáticas: Medicine, general & internal Medicine (miscellaneous) Medicine (all)
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: helena.castane@estudiants.urv.cat jorge.joven@urv.cat
Identificador del autor: 0000-0003-2749-4541
Fecha de alta del registro: 2024-08-03
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://www.mdpi.com/2077-0383/12/2/679
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Journal Of Clinical Medicine. 12 (2):
Referencia de l'ítem segons les normes APA: Espinel, E; Azancot, MA; Gomez, A; Beneria, A; Caraben, A; Andurell, L; Delgado, P; Castane, H; Joven, J; Seron, D (2023). Compliance to Multidisciplinary Lifestyle Intervention Decreases Blood Pressure in Patients with Resistant Hypertension: A Cross-Sectional Pilot Study. Journal Of Clinical Medicine, 12(2), -. DOI: 10.3390/jcm12020679
DOI del artículo: 10.3390/jcm12020679
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2023
Tipo de publicación: Journal Publications
Repositori URV