Autor según el artículo: Navarro-Masip, E; Manocchio, F; Rodriguez, RM; Bravo, FI; Torres-Fuentes, C; Muguerza, B; Aragones, G
Departamento: Bioquímica i Biotecnologia
Autor/es de la URV: Aragonès Bargalló, Gerard / Bravo Vázquez, Francisca Isabel / Manocchio, Francesca / Muguerza Marquínez, Maria Begoña / Navarro Masip, Èlia / RODRÍGUEZ SÁNCHEZ, ROSA MARIA / Torres Fuentes, Cristina
Palabras clave: Lipolysis Lipid-metabolism Corticosterone Biological rhythms Adiponectin (poly)phenols white mass lipolysis leptin glycerol food-intake extract density corticosterone biological rhythms adiponectin (poly)phenols
Resumen: Variations in photoperiod patterns drive metabolic adaptations in mammals, involving important changes in body weight and adiposity. Moreover, (poly)phenols can help heterotrophs adopt metabolic adaptations to face the upcoming environmental conditions. Particularly, proanthocyanidins from grape-seeds show photoperiod-dependent effects on different metabolic parameters. The present study aims to explore whether grape-seed proanthocyanidin extract (GSPE) consumption differently affects the expression of metabolic markers in WAT (subcutaneous and visceral depots) and BAT in a photoperiod-dependent manner.GSPE (25 mg kg-1 day-1 ) is orally administrated for 4 weeks to healthy rats exposed to three photoperiods (L6, L12, and L18). In WAT, GSPE consumption significantly upregulates the expression of lipolytic genes in all photoperiods, being accompanied by increased serum concentrations of glycerol and corticosterone only under the L6 photoperiod. Moreover, adiponectin mRNA levels are significantly upregulated in response to GSPE regardless of the photoperiod, whereas Tnfα and Il6 expression are only downregulated in L6 and L18 photoperiods but not in L12. In BAT, GSPE upregulates Pgc1α expression in all groups, whereas the expression of Pparα is only increased in L18.The results indicate that GSPE modulates the expression of important metabolic markers of WAT and BAT in a photoperiod-dependent manner.© 2023 The Authors. Molecular Nutrition & Food Research published by Wiley-VCH GmbH.
Áreas temáticas: Saúde coletiva Química Nutrição Medicina veterinaria Medicina ii Medicina i Interdisciplinar Food science & technology Food science Farmacia Educação física Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología Biotechnology Astronomia / física
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: francesca.manocchio@urv.cat francesca.manocchio@urv.cat francesca.manocchio@urv.cat elia.navarro@estudiants.urv.cat elia.navarro@estudiants.urv.cat franciscaisabel.bravo@urv.cat gerard.aragones@urv.cat begona.muguerza@urv.cat cristina.torres@urv.cat
Identificador del autor: 0000-0002-6468-3088 0000-0001-7384-8588 0000-0002-2917-6910
Fecha de alta del registro: 2024-09-21
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Molecular Nutrition & Food Research. 67 (17): e2300035-e2300035
Referencia de l'ítem segons les normes APA: Navarro-Masip, E; Manocchio, F; Rodriguez, RM; Bravo, FI; Torres-Fuentes, C; Muguerza, B; Aragones, G (2023). Photoperiod-Dependent Effects of Grape-Seed Proanthocyanidins on Adipose Tissue Metabolic Markers in Healthy Rats. Molecular Nutrition & Food Research, 67(17), e2300035-e2300035. DOI: 10.1002/mnfr.202300035
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2023
Tipo de publicación: Journal Publications
Repositori URV