Articles producció científica> Medicina i Cirurgia

Association between exposure to air pollution and blood lipids in the general population of Spain

  • Datos identificativos

    Identificador: imarina:9330542
    Autores:
    Valdés SDoulatram-Gamgaram VMaldonado-Araque CGarcía-Escobar EGarcía-Serrano SOualla-Bachiri WGarcía-Vivanco MGarrido JLGil VMartín-Llorente FCalle-Pascual ACastaño LDelgado EMenéndez EFranch-Nadal JGaztambide SGirbés JChaves FJGalán-García JLAguilera-Venegas GVallvé JCAmigó NGuardiola MRibalta JRojo-Martínez G
    Resumen:
    We aimed to assess the associations of exposure to air pollutants and standard and advanced lipoprotein measures, in a nationwide sample representative of the adult population of Spain.We included 4647 adults (>18 years), participants in the national, cross-sectional, population-based di@bet.es study, conducted in 2008-2010. Standard lipid measurements were analysed on an Architect C8000 Analyzer (Abbott Laboratories SA). Lipoprotein analysis was made by an advanced 1 H-NMR lipoprotein test (Liposcale®). Participants were assigned air pollution concentrations for particulate matter <10 μm (PM10 ), <2.5 μm (PM2.5 ) and nitrogen dioxide (NO2 ), corresponding to the health examination year, obtained by modelling combined with measurements taken at air quality stations (CHIMERE chemistry-transport model).In multivariate linear regression models, each IQR increase in PM10 , PM2.5 and NO2 was associated with 3.3%, 3.3% and 3% lower levels of HDL-c and 1.3%, 1.4% and 1.1% lower HDL particle (HDL-p) concentrations (p < .001 for all associations). In multivariate logistic regression, there was a significant association between PM10 , PM2.5 and NO2 concentrations and the odds of presenting low HDL-c (<40 mg/dL), low HDL-p (
  • Otros:

    Autor según el artículo: Valdés S; Doulatram-Gamgaram V; Maldonado-Araque C; García-Escobar E; García-Serrano S; Oualla-Bachiri W; García-Vivanco M; Garrido JL; Gil V; Martín-Llorente F; Calle-Pascual A; Castaño L; Delgado E; Menéndez E; Franch-Nadal J; Gaztambide S; Girbés J; Chaves FJ; Galán-García JL; Aguilera-Venegas G; Vallvé JC; Amigó N; Guardiola M; Ribalta J; Rojo-Martínez G
    Departamento: Medicina i Cirurgia Ciències Mèdiques Bàsiques
    Autor/es de la URV: Guardiola Guionnet, Montserrat / Ribalta Vives, Josep / Vallvé Torrente, Joan Carles
    Palabras clave: Triglyceride Lipoprotein Lipids Hdl Cholesterol Air pollution
    Resumen: We aimed to assess the associations of exposure to air pollutants and standard and advanced lipoprotein measures, in a nationwide sample representative of the adult population of Spain.We included 4647 adults (>18 years), participants in the national, cross-sectional, population-based di@bet.es study, conducted in 2008-2010. Standard lipid measurements were analysed on an Architect C8000 Analyzer (Abbott Laboratories SA). Lipoprotein analysis was made by an advanced 1 H-NMR lipoprotein test (Liposcale®). Participants were assigned air pollution concentrations for particulate matter <10 μm (PM10 ), <2.5 μm (PM2.5 ) and nitrogen dioxide (NO2 ), corresponding to the health examination year, obtained by modelling combined with measurements taken at air quality stations (CHIMERE chemistry-transport model).In multivariate linear regression models, each IQR increase in PM10 , PM2.5 and NO2 was associated with 3.3%, 3.3% and 3% lower levels of HDL-c and 1.3%, 1.4% and 1.1% lower HDL particle (HDL-p) concentrations (p < .001 for all associations). In multivariate logistic regression, there was a significant association between PM10 , PM2.5 and NO2 concentrations and the odds of presenting low HDL-c (<40 mg/dL), low HDL-p (<p25) and higher LDL particle (LDL-p) concentrations (≥p75). In subgroup analyses there were stronger associations between PM10 and NO2 and low HDL-p in men (p for interaction .008 and .034), and between NO2 and low HDL-p in individuals with obesity (p for interaction .015).Our study shows an association between the exposure to air pollutants and blood lipids in the general population of Spain, suggesting a link to atherosclerosis.© 2023 The Authors. European Journal of Clinical Investigation published by John Wiley & Sons Ltd on behalf of Stichting European Society for Clinical Investigation Journal Foundation.
    Áreas temáticas: Saúde coletiva Odontología Nutrição Medicine, research & experimental Medicine, general & internal Medicine (miscellaneous) Medicina ii Medicina i Interdisciplinar General medicine Farmacia Educação física Clinical biochemistry Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Biotecnología Biochemistry
    Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
    Direcció de correo del autor: jc.vallve@urv.cat jc.vallve@urv.cat montse.guardiola@urv.cat josep.ribalta@urv.cat
    Identificador del autor: 0000-0002-9696-7384 0000-0002-8879-4719
    Fecha de alta del registro: 2024-08-03
    Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
    Enlace a la fuente original: https://onlinelibrary.wiley.com/doi/10.1111/eci.14101
    URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referencia al articulo segun fuente origial: European Journal Of Clinical Investigation. 54 (2): e14101-e14101
    Referencia de l'ítem segons les normes APA: Valdés S; Doulatram-Gamgaram V; Maldonado-Araque C; García-Escobar E; García-Serrano S; Oualla-Bachiri W; García-Vivanco M; Garrido JL; Gil V; Martín- (2024). Association between exposure to air pollution and blood lipids in the general population of Spain. European Journal Of Clinical Investigation, 54(2), e14101-e14101. DOI: 10.1111/eci.14101
    DOI del artículo: 10.1111/eci.14101
    Entidad: Universitat Rovira i Virgili
    Año de publicación de la revista: 2024
    Tipo de publicación: Journal Publications
  • Palabras clave:

    Biochemistry,Clinical Biochemistry,Medicine (Miscellaneous),Medicine, General & Internal,Medicine, Research & Experimental
    Triglyceride
    Lipoprotein
    Lipids
    Hdl
    Cholesterol
    Air pollution
    Saúde coletiva
    Odontología
    Nutrição
    Medicine, research & experimental
    Medicine, general & internal
    Medicine (miscellaneous)
    Medicina ii
    Medicina i
    Interdisciplinar
    General medicine
    Farmacia
    Educação física
    Clinical biochemistry
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Biotecnología
    Biochemistry
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