Autor según el artículo: Hernandez, Victor; Hansen, Christian Ronn; Widesott, Lamberto; Back, Anna; Canters, Richard; Fusella, Marco; Gotstedt, Julia; Jurado-Bruggeman, Diego; Mukumoto, Nobutaka; Kaplan, Laura Patricia; Koniarova, Irena; Piotrowski, Tomasz; Placidi, Lorenzo; Vaniqui, Ana; Jornet, Nuria
Departamento: Ciències Mèdiques Bàsiques
Autor/es de la URV: Hernandez Masgrau, Victor
Palabras clave: Treatment uncertainties Robustness Robust optimisation Robust evaluation Range uncertainties Radiation-therapy Plan quality Normal tissue Modulated proton therapy Margins Index Imrt Head Dose metrics Complexity metrics Complexity Aperture complexity
Resumen: Plan evaluation is a key step in the radiotherapy treatment workflow. Central to this step is the assessment of treatment plan quality. Hence, it is important to agree on what we mean by plan quality and to be fully aware of which parameters it depends on. We understand plan quality in radiotherapy as the clinical suitability of the delivered dose distribution that can be realistically expected from a treatment plan. Plan quality is commonly assessed by evaluating the dose distribution calculated by the treatment planning system (TPS). Evaluating the 3D dose distribution is not easy, however; it is hard to fully evaluate its spatial characteristics and we still lack the knowledge for personalising the prediction of the clinical outcome based on individual patient characteristics. This advocates for standardisation and systematic collection of clinical data and outcomes after radiotherapy. Additionally, the calculated dose distribution is not exactly the dose delivered to the patient due to uncertainties in the dose calculation and the treatment delivery, including variations in the patient set-up and anatomy. Consequently, plan quality also depends on the robustness and complexity of the treatment plan. We believe that future work and consensus on the best metrics for quality indices are required. Better tools are needed in TPSs for the evaluation of dose distributions, for the robust evaluation and optimisation of treatment plans, and for controlling and reporting plan complexity. Implementation of such tools and a better understanding of these concepts will facilitate the handling of these characteristics in clinical practice and be helpful to increase the overall quality of treatment plans in radiotherapy. (C) 2020 The Authors. Published by Elsevier B.V.
Áreas temáticas: Saúde coletiva Radiology, nuclear medicine and imaging Radiology, nuclear medicine & medical imaging Oncology Odontología Medicina ii Medicina i Interdisciplinar Hematology General medicine Engenharias iv Engenharias ii Ciências biológicas ii Ciências biológicas i Astronomia / física
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: victor.hernandez@urv.cat
Identificador del autor: 0000-0003-3770-8486
Fecha de alta del registro: 2025-03-03
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Radiotherapy And Oncology. 153 26-33
Referencia de l'ítem segons les normes APA: Hernandez, Victor; Hansen, Christian Ronn; Widesott, Lamberto; Back, Anna; Canters, Richard; Fusella, Marco; Gotstedt, Julia; Jurado-Bruggeman, Diego; (2020). What is plan quality in radiotherapy? The importance of evaluating dose metrics, complexity, and robustness of treatment plans. Radiotherapy And Oncology, 153(), 26-33. DOI: 10.1016/j.radonc.2020.09.038
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2020
Tipo de publicación: Journal Publications
Repositori URV